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ChemicalBook >> CAS DataBase List >> 4-Aminopyridine

4-Aminopyridine

4-Aminopyridine price.
  • $25 - $744
  • Product name: 4-Aminopyridine
  • CAS: 504-24-5
  • MF: C5H6N2
  • MW: 94.11
  • EINECS:207-987-9
  • MDL Number:MFCD00006439
  • Synonyms:4-amino-pyridin ;Avitrol 200;avitrol200 ;Compound 1861;Frampridine;mi-w-3 ;4-AP;4APY
20 prices
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  • Alfa Aesar
  • Cayman Chemical
  • Sigma-Aldrich
  • TCI Chemical

Package

  • 1g
  • 5g
  • 8011110010
  • 200mg
  • 10g
  • 8011110025
  • 25g
  • 50g
  • 100g
  • 250g
  • 500g
  • 1000g
  • ManufacturerAlfa Aesar
  • Product numberJ61470
  • Product description4-Aminopyridine, 99+%
  • Packaging25g
  • Price$54.9
  • Updated2019-12-02
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberA12405
  • Product description4-Aminopyridine, 98%
  • Packaging50g
  • Price$55.3
  • Updated2019-12-02
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ61470
  • Product description4-Aminopyridine, 99+%
  • Packaging100g
  • Price$154
  • Updated2019-12-02
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberA12405
  • Product description4-Aminopyridine, 98%
  • Packaging250g
  • Price$219
  • Updated2019-12-02
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberA12405
  • Product description4-Aminopyridine, 98%
  • Packaging1000g
  • Price$744
  • Updated2019-12-02
  • Buy
  • ManufacturerCayman Chemical
  • Product number18511
  • Product description4-Aminopyridine ≥95%
  • Packaging100g
  • Price$78
  • Updated2018-11-13
  • Buy
  • ManufacturerCayman Chemical
  • Product number18511
  • Product description4-Aminopyridine ≥95%
  • Packaging10g
  • Price$25
  • Updated2018-11-13
  • Buy
  • ManufacturerCayman Chemical
  • Product number18511
  • Product description4-Aminopyridine ≥95%
  • Packaging25g
  • Price$34
  • Updated2018-11-13
  • Buy
  • ManufacturerCayman Chemical
  • Product number18511
  • Product description4-Aminopyridine ≥95%
  • Packaging50g
  • Price$48
  • Updated2018-11-13
  • Buy
  • ManufacturerSigma-Aldrich
  • Product number8.01111
  • Product description4-Aminopyridine for synthesis. CAS 504-24-5, chemical formula 4-(NH )C H N., for synthesis
  • Packaging8011110010
  • Price$53.6
  • Updated2019-12-02
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberA78403
  • Product description4-Aminopyridine 98%
  • Packaging25g
  • Price$35.9
  • Updated2019-12-02
  • Buy
  • ManufacturerSigma-Aldrich
  • Product number36687
  • Product description4-Aminopyridine PESTANAL
  • Packaging1g
  • Price$28.2
  • Updated2019-12-02
  • Buy
  • ManufacturerSigma-Aldrich
  • Product number275875
  • Product description4-Aminopyridine ≥99%
  • Packaging1g
  • Price$28.2
  • Updated2019-12-02
  • Buy
  • ManufacturerSigma-Aldrich
  • Product number275875
  • Product description4-Aminopyridine ≥99%
  • Packaging5g
  • Price$79.7
  • Updated2019-12-02
  • Buy
  • ManufacturerSigma-Aldrich
  • Product number8.01111
  • Product description4-Aminopyridine for synthesis. CAS 504-24-5, chemical formula 4-(NH )C H N., for synthesis
  • Packaging8011110025
  • Price$105
  • Updated2019-12-02
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberA78403
  • Product description4-Aminopyridine 98%
  • Packaging100g
  • Price$118
  • Updated2019-12-02
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Alfa Aesar J61470 4-Aminopyridine, 99+% 25g $54.9 2019-12-02 Buy
Alfa Aesar A12405 4-Aminopyridine, 98% 50g $55.3 2019-12-02 Buy
Alfa Aesar J61470 4-Aminopyridine, 99+% 100g $154 2019-12-02 Buy
Alfa Aesar A12405 4-Aminopyridine, 98% 250g $219 2019-12-02 Buy
Alfa Aesar A12405 4-Aminopyridine, 98% 1000g $744 2019-12-02 Buy
Cayman Chemical 18511 4-Aminopyridine ≥95% 100g $78 2018-11-13 Buy
Cayman Chemical 18511 4-Aminopyridine ≥95% 10g $25 2018-11-13 Buy
Cayman Chemical 18511 4-Aminopyridine ≥95% 25g $34 2018-11-13 Buy
Cayman Chemical 18511 4-Aminopyridine ≥95% 50g $48 2018-11-13 Buy
Sigma-Aldrich 8.01111 4-Aminopyridine for synthesis. CAS 504-24-5, chemical formula 4-(NH )C H N., for synthesis 8011110010 $53.6 2019-12-02 Buy
Sigma-Aldrich A78403 4-Aminopyridine 98% 25g $35.9 2019-12-02 Buy
Sigma-Aldrich 36687 4-Aminopyridine PESTANAL 1g $28.2 2019-12-02 Buy
Sigma-Aldrich 275875 4-Aminopyridine ≥99% 1g $28.2 2019-12-02 Buy
Sigma-Aldrich 275875 4-Aminopyridine ≥99% 5g $79.7 2019-12-02 Buy
Sigma-Aldrich 8.01111 4-Aminopyridine for synthesis. CAS 504-24-5, chemical formula 4-(NH )C H N., for synthesis 8011110025 $105 2019-12-02 Buy
Sigma-Aldrich A78403 4-Aminopyridine 98% 100g $118 2019-12-02 Buy

Properties

Melting point: :157 °C
Boiling point: :273 °C(lit.)
Density  :1.26
refractive index  :1.5560 (estimate)
Flash point: :156°C
storage temp.  : 0-6°C
solubility  :H2O: soluble50mg/mL, clear, colorless
pka :9.114(at 25℃)
form  :Crystalline Powder, Solid or Crystals
color  :White to faint grey to light yellow
Water Solubility  :Soluble in water(112 g/L at 20 deg C). Soluble in ethyl ether, benzene. Slightly soluble in ligroin. Very soluble in ethanol. Soluble in methanol, acetone, tetrahydrofuran, isopropanol, acetonitrile, N,N-dimethylformamide, dimethylsulfoxide, and ethanol.
Merck  :14,3933
BRN  :105782
InChIKey :NUKYPUAOHBNCPY-UHFFFAOYSA-N
CAS DataBase Reference :504-24-5(CAS DataBase Reference)
NIST Chemistry Reference :4-Pyridinamine(504-24-5)
EPA Substance Registry System :4-Aminopyridine (504-24-5)

Safety Information

Symbol(GHS):
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H300 Fatal if swallowed Acute toxicity,oral Category 1, 2 Danger P264, P270, P301+P310, P321, P330,P405, P501
H311 Toxic in contact with skin Acute toxicity,dermal Category 3 Danger P280, P302+P352, P312, P322, P361,P363, P405, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
H370 Causes damage to organs Specific target organ toxicity, single exposure Category 1 Danger P260, P264, P270, P307+P311, P321,P405, P501
H372 Causes damage to organs through prolonged or repeated exposure Specific target organ toxicity, repeated exposure Category 1 Danger P260, P264, P270, P314, P501
H401 Toxic to aquatic life Hazardous to the aquatic environment, acute hazard Category 2 P273, P501
H411 Toxic to aquatic life with long lasting effects Hazardous to the aquatic environment, long-term hazard Category 2
Precautionary statements:
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P273 Avoid release to the environment.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P391 Collect spillage. Hazardous to the aquatic environment
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P307+P311 IF exposed: call a POISON CENTER or doctor/physician.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

4-Aminopyridine (4-AP) is a non-selective blocker of voltage-dependent K+-channels (Kv proteins in the KCN gene family). It has greatest potency at Kv1 (KCNA) and Kv3 (KCNC) family members (IC50s = 290, 590, 195, 13, 29, and 100 μM for subunits 1.1, 1.2, 1.3, 1.4, 3.1, and 3.2, respectively). 4-AP also blocks Kv2 and Kv4 subunits at millimolar concentrations. When administered orally, 4-AP has benefits against multiple sclerosis, while injection into the brain produces epileptiform activity and can be used to study seizures.

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