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ChemicalBook >> CAS DataBase List >> Besifloxacin hydrochloride

Besifloxacin hydrochloride

Besifloxacin hydrochloride price.
  • $44 - $1871.1
  • Product name: Besifloxacin hydrochloride
  • CAS: 405165-61-9
  • MF: C19H22Cl2FN3O3
  • MW: 430.3
  • EINECS:696-612-6
  • MDL Number:MFCD14636632
  • Synonyms:(R)-7-(3-AMinohexahydro-1H-azepin-1-yl)-8-chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-quinolin-3-carboxylic acid HCl;3-Quinolinecarboxylic acid, 7-[(3R)-3-aMinohexahydro-1H-azepin-1-yl]-8-chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-, Monohydrochloride (9CI);(R)-7-(3-aMinoazepan-1-yl)-8-chloro-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid hydrochloride;Besifloxacin HCl;Unii-7506A6J57t;(R)-7-(3-Aminohexahydro-1H-azepin-1-yl)-8-chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid hydrochloride;Besifloxacin hydrochloride;Becifloxacin Hydrochloride
21 prices
Selected condition:
Brand
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Biorbyt Ltd
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • Crysdot
  • DC Chemicals
  • TRC
  • Usbiological
Package
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100MG
  • 250mg
  • 500mg
  • 1g
  • ManufacturerAmbeed
  • Product numberA263240
  • Product descriptionBesifloxacinhydrochloride 98+%
  • Packaging10mg
  • Price$51
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA263240
  • Product descriptionBesifloxacinhydrochloride 98+%
  • Packaging250mg
  • Price$520
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0007512
  • Product descriptionBESIFLOXACIN HYDROCHLORIDE 95.00%
  • Packaging10MG
  • Price$191.1
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0007512
  • Product descriptionBESIFLOXACIN HYDROCHLORIDE 95.00%
  • Packaging100MG
  • Price$1871.1
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB1895
  • Product descriptionBesifloxacinHCl
  • Packaging25mg
  • Price$110
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB1895
  • Product descriptionBesifloxacinHCl
  • Packaging50mg
  • Price$200
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB1895
  • Product descriptionBesifloxacinHCl
  • Packaging500mg
  • Price$836
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb180791
  • Product descriptionBesifloxacin HCl >99%
  • Packaging100mg
  • Price$606.9
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb180791
  • Product descriptionBesifloxacin HCl >99%
  • Packaging250mg
  • Price$912.9
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb180791
  • Product descriptionBesifloxacin HCl >99%
  • Packaging1g
  • Price$1802
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number23692
  • Product descriptionBesifloxacin (hydrochloride) ≥95%
  • Packaging5mg
  • Price$44
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number23692
  • Product descriptionBesifloxacin (hydrochloride) ≥95%
  • Packaging10mg
  • Price$84
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number23692
  • Product descriptionBesifloxacin (hydrochloride) ≥95%
  • Packaging25mg
  • Price$193
  • Updated2024-03-01
  • Buy
  • ManufacturerChemenu
  • Product numberCM144671
  • Product description(R)-7-(3-aminoazepan-1-yl)-8-chloro-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylicacidhydrochloride 98%
  • Packaging100mg
  • Price$346
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0713
  • Product descriptionBesifloxacinHydrochloride 98.64%
  • Packaging10mg
  • Price$60
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0713
  • Product descriptionBesifloxacinHydrochloride 98.64%
  • Packaging50mg
  • Price$240
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Ambeed A263240 Besifloxacinhydrochloride 98+% 10mg $51 2021-12-16 Buy
Ambeed A263240 Besifloxacinhydrochloride 98+% 250mg $520 2021-12-16 Buy
American Custom Chemicals Corporation API0007512 BESIFLOXACIN HYDROCHLORIDE 95.00% 10MG $191.1 2021-12-16 Buy
American Custom Chemicals Corporation API0007512 BESIFLOXACIN HYDROCHLORIDE 95.00% 100MG $1871.1 2021-12-16 Buy
ApexBio Technology B1895 BesifloxacinHCl 25mg $110 2021-12-16 Buy
ApexBio Technology B1895 BesifloxacinHCl 50mg $200 2021-12-16 Buy
ApexBio Technology B1895 BesifloxacinHCl 500mg $836 2021-12-16 Buy
Biorbyt Ltd orb180791 Besifloxacin HCl >99% 100mg $606.9 2021-12-16 Buy
Biorbyt Ltd orb180791 Besifloxacin HCl >99% 250mg $912.9 2021-12-16 Buy
Biorbyt Ltd orb180791 Besifloxacin HCl >99% 1g $1802 2021-12-16 Buy
Cayman Chemical 23692 Besifloxacin (hydrochloride) ≥95% 5mg $44 2024-03-01 Buy
Cayman Chemical 23692 Besifloxacin (hydrochloride) ≥95% 10mg $84 2024-03-01 Buy
Cayman Chemical 23692 Besifloxacin (hydrochloride) ≥95% 25mg $193 2024-03-01 Buy
Chemenu CM144671 (R)-7-(3-aminoazepan-1-yl)-8-chloro-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylicacidhydrochloride 98% 100mg $346 2021-12-16 Buy
ChemScene CS-0713 BesifloxacinHydrochloride 98.64% 10mg $60 2021-12-16 Buy
ChemScene CS-0713 BesifloxacinHydrochloride 98.64% 50mg $240 2021-12-16 Buy

Properties

Melting point :>210°C (dec.)
storage temp. :Inert atmosphere,2-8°C
solubility :Methanol (Slightly, Heated, Sonicated), Water (Slightly, Heated, Sonicated)
form :Solid
color :Off-White to Light Beige

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Besifloxacin is a new fluoroquinolone antibacterial for ophthalmic use. It is indicated for the treatment of bacterial conjunctivitis, one of the most common ocular infections encountered in the primary care setting. Although the previously marketed fluoroquinolones ciprofloxacin, levofloxacin, ofloxacin, gatifloxacin, and moxifloxacin have been widely used to treat bacterial conjunctivitis, their continued utility is hampered by the emergence of resistance among key ocular isolates such as Staphylococcus aureus. Besifloxacin is the first fluoroquinolone developed exclusively for topical ophthalmic use. Unlike the previously marketed fluoroquinolones, besifloxacin has not been used systemically and is not in development as a systemic agent. Its exclusive indication as a topical agent is expected to reduce the overall environmental exposure of bacteria to besifloxacin, which may contribute to a lower risk for the emergence of bacterial resistance. Fluoroquinolones derive their antibacterial activity via inhibition of two essential bacterial enzymes, DNA gyrase and topoisomerase IV, which regulate processes of DNA replication. Besifloxacin inhibits DNA gyrase and topoisomerase IV from Streptococcus pneumoniae (IC50 = 1 and 0.4 mg/ L, respectively) and Escherichia coli (IC50 = 1 and 10 mg/L, respectively).

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