(4-Chloro-3-nitrophenyl)(4-(2-fluorophenyl)piperazin-1-yl)Methanone
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- $32 - $460
- Product name: (4-Chloro-3-nitrophenyl)(4-(2-fluorophenyl)piperazin-1-yl)Methanone
- CAS: 432020-20-7
- MF: C17H15ClFN3O3
- MW: 363.7707032
- EINECS:
- MDL Number:MFCD03575351
- Synonyms:(4-Chloro-3-nitrophenyl)(4-(2-fluorophenyl)piperazin-1-yl)Methanone;1-(4-Chloro-3-nitrobenzoyl)-4-(2-fluorophenyl)-piperazine;SID: 164348711;SMI481;Methanone, (4-chloro-3-nitrophenyl)[4-(2-fluorophenyl)-1-piperazinyl]-;NPPM 6748481;NPPM 6748-481;NPPM6748481
10 prices
Selected condition：
Brand
- AK Scientific
- Cayman Chemical
- Sigma-Aldrich
- TRC
- Usbiological
Package
- 1mg
- 5mg
- 10mg
- 25mg
- 50mg
- ManufacturerAK Scientific
- Product numberSYN5232
- Product descriptionSMI481
- Packaging50mg
- Price$460
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number17637
- Product descriptionSMI-481 ≥98%
- Packaging1mg
- Price$32
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number17637
- Product descriptionSMI-481 ≥98%
- Packaging5mg
- Price$93
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number17637
- Product descriptionSMI-481 ≥98%
- Packaging10mg
- Price$169
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number17637
- Product descriptionSMI-481 ≥98%
- Packaging25mg
- Price$381
- Updated2024-03-01
- Buy
- ManufacturerSigma-Aldrich
- Product numberSML1090
- Product descriptionSMI481 ≥98% (HPLC)
- Packaging5mg
- Price$102
- Updated2022-05-15
- Buy
- ManufacturerSigma-Aldrich
- Product numberSML1090
- Product descriptionSMI481 ≥98% (HPLC)
- Packaging25mg
- Price$410
- Updated2022-05-15
- Buy
- ManufacturerTRC
- Product numberS566020
- Product descriptionSMI-481
- Packaging1mg
- Price$55
- Updated2021-12-16
- Buy
- ManufacturerTRC
- Product numberS566020
- Product descriptionSMI-481
- Packaging5mg
- Price$85
- Updated2021-12-16
- Buy
- ManufacturerUsbiological
- Product number466182
- Product descriptionSMI-481
- Packaging1mg
- Price$319
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | SYN5232 | SMI481 | 50mg | $460 | 2021-12-16 | Buy |
| Cayman Chemical | 17637 | SMI-481 ≥98% | 1mg | $32 | 2024-03-01 | Buy |
| Cayman Chemical | 17637 | SMI-481 ≥98% | 5mg | $93 | 2024-03-01 | Buy |
| Cayman Chemical | 17637 | SMI-481 ≥98% | 10mg | $169 | 2024-03-01 | Buy |
| Cayman Chemical | 17637 | SMI-481 ≥98% | 25mg | $381 | 2024-03-01 | Buy |
| Sigma-Aldrich | SML1090 | SMI481 ≥98% (HPLC) | 5mg | $102 | 2022-05-15 | Buy |
| Sigma-Aldrich | SML1090 | SMI481 ≥98% (HPLC) | 25mg | $410 | 2022-05-15 | Buy |
| TRC | S566020 | SMI-481 | 1mg | $55 | 2021-12-16 | Buy |
| TRC | S566020 | SMI-481 | 5mg | $85 | 2021-12-16 | Buy |
| Usbiological | 466182 | SMI-481 | 1mg | $319 | 2021-12-16 | Buy |
Properties
Boiling point :543.3±50.0 °C(Predicted)
Density :1.411±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: soluble5mg/mL, clear
pka :1.04±0.10(Predicted)
form :powder
color :white to beige
Density :1.411±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: soluble5mg/mL, clear
pka :1.04±0.10(Predicted)
form :powder
color :white to beige
Safety Information
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| Signal word: | Warning | ||||||||||||||||||||||||||||
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Description
Phosphatidylinositol (PtdIns) transfer proteins (PITPs) mediate the exchange of PtdIns and phosphatidylcholine between membranes, a step required for a wide array of cellular processes including cell division. SMI-481 is an inhibitor of the yeast PITP Sec14, blocking both Sec14-mediated transfer of [3H]-PtdIns in vitro and growth (IC50s = 0.21 and 2.87 μM, respectively). Suppression of Sec14 expression leads to proportional reduction in SMI-481 inhibition, suggesting that SMI-481 acts specifically through Sec14. Moreover, SMI-481 does not affect [3H]-PtdIns transfer mediated by other yeast PITPs.Related product price
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