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ChemicalBook >> CAS DataBase List >> 2-[1-[4-[2-(4-Chlorophenoxy)acetyl]-1-piperazinyl]ethyl]-3-(2-ethoxyphenyl)-4(3H)-Quinazolinone

2-[1-[4-[2-(4-Chlorophenoxy)acetyl]-1-piperazinyl]ethyl]-3-(2-ethoxyphenyl)-4(3H)-Quinazolinone

2-[1-[4-[2-(4-Chlorophenoxy)acetyl]-1-piperazinyl]ethyl]-3-(2-ethoxyphenyl)-4(3H)-Quinazolinone price.
  • $44 - $2691.1
  • Product name: 2-[1-[4-[2-(4-Chlorophenoxy)acetyl]-1-piperazinyl]ethyl]-3-(2-ethoxyphenyl)-4(3H)-Quinazolinone
  • CAS: 571203-78-6
  • MF: C30H31ClN4O4
  • MW: 547.04
  • EINECS:
  • MDL Number:MFCD09837984
  • Synonyms:2-[1-[4-[2-(4-Chlorophenoxy)acetyl]-1-piperazinyl]ethyl]-3-(2-ethoxyphenyl)-4(3H)-Quinazolinone;4(3H)-Quinazolinone, 2-[1-[4-[2-(4-chlorophenoxy)acetyl]-1-piperazinyl]ethyl]-3-(2-ethoxyphenyl)-;2-[1-[4-[2-(4-Chlorophenoxy)acetyl]-1-piperazinyl]ethyl]-3-(2-ethoxyphenyl)-4(3H)-quinazolinone Erastin;2-(1-(4-(2-(4-Chlorophenoxy)acetyl)piperazin-1-yl)ethyl)-3-(2-ethoxyphenyl)quinazolin-4(3H)-on;Erastin;Erastin - CAS 571203-78-6 - Calbiochem;2-[1-[4-[2-(4-Chlorophenoxy)acetyl]-1-piperazinyl]ethyl]-3-(2-ethoxyphenyl)-4(3H)-Quinazolinone USP/EP/BP;CS-1430
31 prices
Selected condition:
Brand
  • American Custom Chemicals Corporation
  • Arctom
  • Biorbyt Ltd
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • Tocris
  • TRC
  • Usbiological
Package
  • 5mg
  • 10
  • 1MG
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 200mg
  • 250mg
  • 1000mg
  • 1g
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0026390
  • Product descriptionErastin 95.00%
  • Packaging1MG
  • Price$148.05
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberCFN60178
  • Product descriptionErastin ≥98%
  • Packaging10mg
  • Price$278
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb546179
  • Product descriptionErastin >98%
  • Packaging5mg
  • Price$173.4
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb546179
  • Product descriptionErastin >98%
  • Packaging25mg
  • Price$455.6
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb181240
  • Product descriptionErastin >98%
  • Packaging100mg
  • Price$838.1
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb181240
  • Product descriptionErastin >98%
  • Packaging250mg
  • Price$1504.5
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb181240
  • Product descriptionErastin >98%
  • Packaging1000mg
  • Price$2691.1
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number17754
  • Product descriptionErastin ≥98%
  • Packaging1mg
  • Price$44
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number17754
  • Product descriptionErastin ≥98%
  • Packaging5mg
  • Price$130
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number17754
  • Product descriptionErastin ≥98%
  • Packaging10mg
  • Price$214
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number17754
  • Product descriptionErastin ≥98%
  • Packaging50mg
  • Price$849
  • Updated2024-03-01
  • Buy
  • ManufacturerChemenu
  • Product numberCM142731
  • Product description2-(1-(4-(2-(4-Chlorophenoxy)acetyl)piperazin-1-yl)ethyl)-3-(2-ethoxyphenyl)quinazolin-4(3H)-one 98%
  • Packaging100mg
  • Price$622
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-1675
  • Product descriptionErastin 99.72%
  • Packaging1mg
  • Price$50
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-1675
  • Product descriptionErastin 99.72%
  • Packaging5mg
  • Price$120
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-1675
  • Product descriptionErastin 99.72%
  • Packaging10mg
  • Price$180
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-1675
  • Product descriptionErastin 99.72%
  • Packaging50mg
  • Price$480
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
American Custom Chemicals Corporation API0026390 Erastin 95.00% 1MG $148.05 2021-12-16 Buy
Arctom CFN60178 Erastin ≥98% 10mg $278 2021-12-16 Buy
Biorbyt Ltd orb546179 Erastin >98% 5mg $173.4 2021-12-16 Buy
Biorbyt Ltd orb546179 Erastin >98% 25mg $455.6 2021-12-16 Buy
Biorbyt Ltd orb181240 Erastin >98% 100mg $838.1 2021-12-16 Buy
Biorbyt Ltd orb181240 Erastin >98% 250mg $1504.5 2021-12-16 Buy
Biorbyt Ltd orb181240 Erastin >98% 1000mg $2691.1 2021-12-16 Buy
Cayman Chemical 17754 Erastin ≥98% 1mg $44 2024-03-01 Buy
Cayman Chemical 17754 Erastin ≥98% 5mg $130 2024-03-01 Buy
Cayman Chemical 17754 Erastin ≥98% 10mg $214 2024-03-01 Buy
Cayman Chemical 17754 Erastin ≥98% 50mg $849 2024-03-01 Buy
Chemenu CM142731 2-(1-(4-(2-(4-Chlorophenoxy)acetyl)piperazin-1-yl)ethyl)-3-(2-ethoxyphenyl)quinazolin-4(3H)-one 98% 100mg $622 2021-12-16 Buy
ChemScene CS-1675 Erastin 99.72% 1mg $50 2021-12-16 Buy
ChemScene CS-1675 Erastin 99.72% 5mg $120 2021-12-16 Buy
ChemScene CS-1675 Erastin 99.72% 10mg $180 2021-12-16 Buy
ChemScene CS-1675 Erastin 99.72% 50mg $480 2021-12-16 Buy

Properties

Boiling point :721.9±70.0 °C(Predicted)
Density :1.28±0.1 g/cm3(Predicted)
storage temp. :-20°C
solubility :DMSO: soluble5mg/mL, clear (warmed)
pka :5.54±0.10(Predicted)
form :White solid
color :white to beige
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
CAS DataBase Reference :571203-78-6

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Erastin, named for eradicator of RAS and ST-expressing cells, is an irreversible antitumor agent that selectively kills cells expressing the small T oncoprotein and oncogenic Ras (IC50s = 1.25-5 μg/ml). It produces non-apoptotic tumor cell death by altering mitochondrial voltage-dependent anion channel gating, allowing cations to enter mitochondria and leading to release of oxidative species causing oxidative cell death.

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