3,5-BIS(1,1-DIMETHYLETHYL)-4-HYDROXY-B,B-DIMETHYL-BENZENEPROPANOL
|
- $44 - $1073.29
- Product name: 3,5-BIS(1,1-DIMETHYLETHYL)-4-HYDROXY-B,B-DIMETHYL-BENZENEPROPANOL
- CAS: 57717-80-3
- MF: C19H32O2
- MW: 292.46
- EINECS:
- MDL Number:MFCD04040028
- Synonyms:CGP 7930;3-(3',5'-DI-TERT-BUTYL-4'-HYDROXY)PHENYL-2,2-DIMETHYLPROPANOL;3,5-BIS(1,1-DIMETHYLETHYL)-4-HYDROXY-B,B-DIMETHYL-BENZENEPROPANOL;3,5-Bis(1,1-dimethylethyl)-4-hydroxy-beta,beta-dimethylbenzenepropanol;3,5-bis(1,1-Dimethylethyl)-4-hydroxy-β,β-dimethyl-benzenepropanol;Benzenepropanol, 3,5-bis(1,1-dimethylethyl)-4-hydroxy-β,β-dimethyl-
11 prices
Selected condition：
Brand
- American Custom Chemicals Corporation
- ApexBio Technology
- Cayman Chemical
- Tocris
- TRC
- Usbiological
Package
- 10
- 5mg
- 1mg
- 50
- 10MG
- 50MG
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0007845
- Product descriptionCGP-7930 95.00%
- Packaging10MG
- Price$665.81
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0007845
- Product descriptionCGP-7930 95.00%
- Packaging50MG
- Price$1073.29
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB6771
- Product descriptionCGP7930
- Packaging10mg
- Price$234
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB6771
- Product descriptionCGP7930
- Packaging50mg
- Price$975
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number29429
- Product descriptionCGP 7930
- Packaging1mg
- Price$44
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number29429
- Product descriptionCGP 7930
- Packaging5mg
- Price$130
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number29429
- Product descriptionCGP 7930
- Packaging10mg
- Price$172
- Updated2024-03-01
- Buy
- ManufacturerTocris
- Product number1513
- Product descriptionCGP7930 ≥98%(HPLC)
- Packaging10
- Price$159
- Updated2021-12-16
- Buy
- ManufacturerTocris
- Product number1513
- Product descriptionCGP7930 ≥98%(HPLC)
- Packaging50
- Price$658
- Updated2021-12-16
- Buy
- ManufacturerTRC
- Product numberC583585
- Product descriptionCGP7930
- Packaging1mg
- Price$85
- Updated2021-12-16
- Buy
- ManufacturerUsbiological
- Product number254943
- Product descriptionCGP 7930
- Packaging10mg
- Price$403
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| American Custom Chemicals Corporation | API0007845 | CGP-7930 95.00% | 10MG | $665.81 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0007845 | CGP-7930 95.00% | 50MG | $1073.29 | 2021-12-16 | Buy |
| ApexBio Technology | B6771 | CGP7930 | 10mg | $234 | 2021-12-16 | Buy |
| ApexBio Technology | B6771 | CGP7930 | 50mg | $975 | 2021-12-16 | Buy |
| Cayman Chemical | 29429 | CGP 7930 | 1mg | $44 | 2024-03-01 | Buy |
| Cayman Chemical | 29429 | CGP 7930 | 5mg | $130 | 2024-03-01 | Buy |
| Cayman Chemical | 29429 | CGP 7930 | 10mg | $172 | 2024-03-01 | Buy |
| Tocris | 1513 | CGP7930 ≥98%(HPLC) | 10 | $159 | 2021-12-16 | Buy |
| Tocris | 1513 | CGP7930 ≥98%(HPLC) | 50 | $658 | 2021-12-16 | Buy |
| TRC | C583585 | CGP7930 | 1mg | $85 | 2021-12-16 | Buy |
| Usbiological | 254943 | CGP 7930 | 10mg | $403 | 2021-12-16 | Buy |
Properties
storage temp. :Desiccate at RT
solubility :DMSO: 22 mg/mL, soluble
form :solid
color :white
solubility :DMSO: 22 mg/mL, soluble
form :solid
color :white
Safety Information
| Symbol(GHS): | ||||||||
|---|---|---|---|---|---|---|---|---|
| Signal word: | ||||||||
| Hazard statements: |
|
|||||||
| Precautionary statements: |
|
Description
CGP 7930 is a positive allosteric modulator of GABAB receptors. It enhances GABA binding with a maximal effect of 143% compared to a GABA-only control in CHO cells membranes expressing the GABAB(1b/2) receptor and enhances GABA binding to rat cortical membranes when used at a concentration of 30 μM. It is selective for GABA binding to heterodimeric GABAB(1b/2) over monomeric GABAB(1b) receptors. CGP 7930 potentiates the efficacy of the GABAB receptor agonist baclofen in decreasing the spontaneous firing rate of dopaminergic neurons in the rat ventral tegmental area (VTA) in vitro (EC50 = 0.27 μM). It also potentiates the sedative-reducing effects induced by the GABAB receptor agonists baclofen and γ-hydroxybutyric acid (GHB) in rats when administered at doses ranging from 10 to 170 mg/kg, effects that can be blocked by the GABAB receptor antagonist SCH 50911. CGP 7930 reduces self-administration of nicotine, alcohol, and cocaine in rodent models. It suppresses the acquisition of alcohol drinking behavior in alcohol-naïve Sardinian alcohol-preferring rats over a five-day period when administered at doses ranging from 25 to 100 mg/kg and transiently reduces the maintenance of alcohol drinking behavior in alcohol-experienced rats at a dose of 100 mg/kg.More related product prices
Related product price
Suppliers and manufacturers
TargetMol Chemicals Inc.
Aladdin Scientific
3B Pharmachem (Wuhan) International Co.,Ltd.
EMMX Biotechnology LLC
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
MedBioPharmaceutical Technology Inc
Changzhou Furuisi Biotechnology Co., Ltd
Shanghai Universal Biotech Co.,Ltd
TargetMol Chemicals Inc.
Nantong QuanYi Biotechnology Co., Ltd