6-O-Benzylguanine
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- $5 - $4010
- Product name: 6-O-Benzylguanine
- CAS: 19916-73-5
- MF: C12H11N5O
- MW: 241.25
- EINECS:1592732-453-0
- MDL Number:MFCD00269931
- Synonyms:O(sup 6)benzylguanidine;2-Amino-6-(benzyloxy)-9H-purine;6-(Benzyloxy)-1H-purin-2-amine;6-(PhenylMethoxy)-9H-purin-2-aMine;NSC 637037;6-oxo -benzylguanine;6-O-Benzylguanine(O6BG);9H-Purin-2-amine,6-(phenylmethoxy)-
43 prices
Selected condition：
Brand
- AccelPharmtech
- AK Scientific
- Alfa Aesar
- Alichem
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Biosynth Carbosynth
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- CSNpharm
- DC Chemicals
- Matrix Scientific
- Medical Isotopes, Inc.
- Sigma-Aldrich
- SynQuest Laboratories
- Usbiological
Package
- 10mg
- 50MG
- 100mg
- 250mg
- 500mg
- 1G
- 5G
- 10g
- 25G
- 50g
- 100g
- 250g
- 500g
- ManufacturerAccelPharmtech
- Product numberC1238
- Product description6-O-Benzylguanine 97.00%
- Packaging1G
- Price$1940
- Updated2021-12-16
- Buy
- ManufacturerAccelPharmtech
- Product numberC1238
- Product description6-O-Benzylguanine 97.00%
- Packaging5G
- Price$2180
- Updated2021-12-16
- Buy
- ManufacturerAccelPharmtech
- Product numberC1238
- Product description6-O-Benzylguanine 97.00%
- Packaging25G
- Price$4010
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberJ92255
- Product description6-O-Benzylguanine
- Packaging1g
- Price$10
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberJ92255
- Product description6-O-Benzylguanine
- Packaging25g
- Price$49
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberJ10132
- Product description6-O-Benzylguanine
- Packaging1g
- Price$79
- Updated2021-12-16
- Buy
- ManufacturerAlfa Aesar
- Product numberH60274
- Product descriptionO6-Benzylguanine, 98%
- Packaging250mg
- Price$47.65
- Updated2024-03-01
- Buy
- ManufacturerAlichem
- Product number19916735
- Product description6-(Benzyloxy)-7H-purin-2-amine
- Packaging25g
- Price$150.48
- Updated2021-12-16
- Buy
- ManufacturerAlichem
- Product number19916735
- Product description6-(Benzyloxy)-7H-purin-2-amine
- Packaging100g
- Price$371.42
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA394978
- Product description6-(Benzyloxy)-7H-purin-2-amine 98%
- Packaging100mg
- Price$5
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA394978
- Product description6-(Benzyloxy)-7H-purin-2-amine 98%
- Packaging1g
- Price$6
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA394978
- Product description6-(Benzyloxy)-7H-purin-2-amine 98%
- Packaging5g
- Price$9
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA394978
- Product description6-(Benzyloxy)-7H-purin-2-amine 98%
- Packaging10g
- Price$16
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA394978
- Product description6-(Benzyloxy)-7H-purin-2-amine 98%
- Packaging25g
- Price$28
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA394978
- Product description6-(Benzyloxy)-7H-purin-2-amine 98%
- Packaging100g
- Price$105
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA394978
- Product description6-(Benzyloxy)-7H-purin-2-amine 98%
- Packaging500g
- Price$421
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AccelPharmtech | C1238 | 6-O-Benzylguanine 97.00% | 1G | $1940 | 2021-12-16 | Buy |
| AccelPharmtech | C1238 | 6-O-Benzylguanine 97.00% | 5G | $2180 | 2021-12-16 | Buy |
| AccelPharmtech | C1238 | 6-O-Benzylguanine 97.00% | 25G | $4010 | 2021-12-16 | Buy |
| AK Scientific | J92255 | 6-O-Benzylguanine | 1g | $10 | 2021-12-16 | Buy |
| AK Scientific | J92255 | 6-O-Benzylguanine | 25g | $49 | 2021-12-16 | Buy |
| AK Scientific | J10132 | 6-O-Benzylguanine | 1g | $79 | 2021-12-16 | Buy |
| Alfa Aesar | H60274 | O6-Benzylguanine, 98% | 250mg | $47.65 | 2024-03-01 | Buy |
| Alichem | 19916735 | 6-(Benzyloxy)-7H-purin-2-amine | 25g | $150.48 | 2021-12-16 | Buy |
| Alichem | 19916735 | 6-(Benzyloxy)-7H-purin-2-amine | 100g | $371.42 | 2021-12-16 | Buy |
| Ambeed | A394978 | 6-(Benzyloxy)-7H-purin-2-amine 98% | 100mg | $5 | 2021-12-16 | Buy |
| Ambeed | A394978 | 6-(Benzyloxy)-7H-purin-2-amine 98% | 1g | $6 | 2021-12-16 | Buy |
| Ambeed | A394978 | 6-(Benzyloxy)-7H-purin-2-amine 98% | 5g | $9 | 2021-12-16 | Buy |
| Ambeed | A394978 | 6-(Benzyloxy)-7H-purin-2-amine 98% | 10g | $16 | 2021-12-16 | Buy |
| Ambeed | A394978 | 6-(Benzyloxy)-7H-purin-2-amine 98% | 25g | $28 | 2021-12-16 | Buy |
| Ambeed | A394978 | 6-(Benzyloxy)-7H-purin-2-amine 98% | 100g | $105 | 2021-12-16 | Buy |
| Ambeed | A394978 | 6-(Benzyloxy)-7H-purin-2-amine 98% | 500g | $421 | 2021-12-16 | Buy |
Properties
Melting point :193(dec.)
Boiling point :459.3±55.0 °C(Predicted)
Density :1.48±0.1 g/cm3(Predicted)
storage temp. :room temp
solubility :methanol: 20 mg/mL
form :solid
pka :7.47±0.20(Predicted)
color :Off-White to Light Yellow
CAS DataBase Reference :19916-73-5(CAS DataBase Reference)
Boiling point :459.3±55.0 °C(Predicted)
Density :1.48±0.1 g/cm3(Predicted)
storage temp. :room temp
solubility :methanol: 20 mg/mL
form :solid
pka :7.47±0.20(Predicted)
color :Off-White to Light Yellow
CAS DataBase Reference :19916-73-5(CAS DataBase Reference)
Safety Information
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Description
O6-Alkylguanine-DNA alkyltransferase (AGT, also known as methylguanine DNA methyltransferase, or MGMT) is a DNA repair protein that directly removes alkyl groups located on the O6-position of guanine from DNA, restoring DNA integrity in a single step. In the process, AGT is alkylated and irreversibly inactivated. O6-Benzylguanine is a guanine analog with antineoplastic activity. It serves as a pseudosubstrate for AGT, transferring a benzyl moiety to the active site cysteine of the enzyme. This leads to irreversible inactivation, with 40% reduction in alkyltransferase activity of recombinant human AGT achieved at 0.06 μM. O6-Benzylguanine is effective in vivo as well as in vitro. Inactivation of AGT increases the chemotherapeutic effectiveness of chloroethylating and methylating agents.More related product prices
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