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ChemicalBook >> CAS DataBase List >> (2E)-N-(1-Acetyl-2,3-dihydro-1H-indol-6-yl)-3-(3-cyanophenyl)-N-[1-(2-cyclopentylethyl)-4-piperidinyl]-2-propenamide

(2E)-N-(1-Acetyl-2,3-dihydro-1H-indol-6-yl)-3-(3-cyanophenyl)-N-[1-(2-cyclopentylethyl)-4-piperidinyl]-2-propenamide

(2E)-N-(1-Acetyl-2,3-dihydro-1H-indol-6-yl)-3-(3-cyanophenyl)-N-[1-(2-cyclopentylethyl)-4-piperidinyl]-2-propenamide price.
  • $44 - $1708
  • Product name: (2E)-N-(1-Acetyl-2,3-dihydro-1H-indol-6-yl)-3-(3-cyanophenyl)-N-[1-(2-cyclopentylethyl)-4-piperidinyl]-2-propenamide
  • CAS: 683746-68-1
  • MF: C32H38N4O2
  • MW: 511
  • EINECS:
  • MDL Number:MFCD19690929
  • Synonyms:(2E)-N-(1-Acetyl-2,3-dihydro-1H-indol-6-yl)-3-(3-cyanophenyl)-N-[1-(2-cyclopentylethyl)-4-piperidinyl]-2-propenamide;JNJ 5207787;trans-N-(1-Acetyl-2,3-dihydro-1H-indol-6-yl)-3-(3-cyanophenyl)-N-[1-(2-cyclopentylethyl)piperidin-4-yl]acrylamide;(E)-N-(1-acetyl-2,3-dihydroindol-6-yl)-3-(3-cyanophenyl)-N-[1-(2-cyclopentylethyl)piperidin-4-yl]prop-2-enamide;2-Propenamide, N-(1-acetyl-2,3-dihydro-1H-indol-6-yl)-3-(3-cyanophenyl)-N-[1-(2-cyclopentylethyl)-4-piperidinyl]-, (2E)-
16 prices
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Brand
  • aablocks
  • AK Scientific
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Cayman Chemical
  • Tocris
  • TRC
Package
  • 10
  • 1mg
  • 5mg
  • 10mg
  • 50mg
  • Manufactureraablocks
  • Product numberAA00FEID
  • Product description(2E)-N-(1-Acetyl-2,3-dihydro-1H-indol-6-yl)-3-(3-cyanophenyl)-N-[1-(2-cyclopentylethyl)-4-piperidinyl]-2-propenamide ≥98%
  • Packaging1mg
  • Price$94
  • Updated2021-12-16
  • Buy
  • Manufactureraablocks
  • Product numberAA00FEID
  • Product description(2E)-N-(1-Acetyl-2,3-dihydro-1H-indol-6-yl)-3-(3-cyanophenyl)-N-[1-(2-cyclopentylethyl)-4-piperidinyl]-2-propenamide ≥98%
  • Packaging5mg
  • Price$217
  • Updated2021-12-16
  • Buy
  • Manufactureraablocks
  • Product numberAA00FEID
  • Product description(2E)-N-(1-Acetyl-2,3-dihydro-1H-indol-6-yl)-3-(3-cyanophenyl)-N-[1-(2-cyclopentylethyl)-4-piperidinyl]-2-propenamide ≥98%
  • Packaging10mg
  • Price$353
  • Updated2021-12-16
  • Buy
  • Manufactureraablocks
  • Product numberAA00FEID
  • Product description(2E)-N-(1-Acetyl-2,3-dihydro-1H-indol-6-yl)-3-(3-cyanophenyl)-N-[1-(2-cyclopentylethyl)-4-piperidinyl]-2-propenamide ≥98%
  • Packaging50mg
  • Price$1269
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number6700CR
  • Product descriptionUnii-OW44B6FA0Y
  • Packaging1mg
  • Price$147
  • Updated2021-12-16
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  • ManufacturerAK Scientific
  • Product number6700CR
  • Product descriptionUnii-OW44B6FA0Y
  • Packaging10mg
  • Price$426
  • Updated2021-12-16
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  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0007699
  • Product description(2E)-N-(1-ACETYL-2,3-DIHYDRO-1H-INDOL-6-YL)-3-(3-CYANOPHENYL)-N-[1-(2-CYCLOPENTYLETHYL)-4-PIPERIDINYL]-2-PROPENAMIDE 95.00%
  • Packaging10MG
  • Price$782.23
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0007699
  • Product description(2E)-N-(1-ACETYL-2,3-DIHYDRO-1H-INDOL-6-YL)-3-(3-CYANOPHENYL)-N-[1-(2-CYCLOPENTYLETHYL)-4-PIPERIDINYL]-2-PROPENAMIDE 95.00%
  • Packaging50MG
  • Price$1546.26
  • Updated2021-12-16
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  • ManufacturerApexBio Technology
  • Product numberB5512
  • Product descriptionJNJ5207787
  • Packaging10mg
  • Price$434
  • Updated2021-12-16
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  • ManufacturerApexBio Technology
  • Product numberB5512
  • Product descriptionJNJ5207787
  • Packaging50mg
  • Price$1708
  • Updated2021-12-16
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  • ManufacturerCayman Chemical
  • Product number13947
  • Product descriptionJNJ-5207787 ≥98%
  • Packaging1mg
  • Price$44
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number13947
  • Product descriptionJNJ-5207787 ≥98%
  • Packaging5mg
  • Price$163
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number13947
  • Product descriptionJNJ-5207787 ≥98%
  • Packaging10mg
  • Price$296
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number13947
  • Product descriptionJNJ-5207787 ≥98%
  • Packaging50mg
  • Price$1184
  • Updated2024-03-01
  • Buy
  • ManufacturerTocris
  • Product number4018
  • Product descriptionJNJ5207787 ≥98%(HPLC)
  • Packaging10
  • Price$293
  • Updated2021-12-16
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  • ManufacturerTRC
  • Product numberJ211383
  • Product descriptionJNJ5207787
  • Packaging50mg
  • Price$1080
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA00FEID (2E)-N-(1-Acetyl-2,3-dihydro-1H-indol-6-yl)-3-(3-cyanophenyl)-N-[1-(2-cyclopentylethyl)-4-piperidinyl]-2-propenamide ≥98% 1mg $94 2021-12-16 Buy
aablocks AA00FEID (2E)-N-(1-Acetyl-2,3-dihydro-1H-indol-6-yl)-3-(3-cyanophenyl)-N-[1-(2-cyclopentylethyl)-4-piperidinyl]-2-propenamide ≥98% 5mg $217 2021-12-16 Buy
aablocks AA00FEID (2E)-N-(1-Acetyl-2,3-dihydro-1H-indol-6-yl)-3-(3-cyanophenyl)-N-[1-(2-cyclopentylethyl)-4-piperidinyl]-2-propenamide ≥98% 10mg $353 2021-12-16 Buy
aablocks AA00FEID (2E)-N-(1-Acetyl-2,3-dihydro-1H-indol-6-yl)-3-(3-cyanophenyl)-N-[1-(2-cyclopentylethyl)-4-piperidinyl]-2-propenamide ≥98% 50mg $1269 2021-12-16 Buy
AK Scientific 6700CR Unii-OW44B6FA0Y 1mg $147 2021-12-16 Buy
AK Scientific 6700CR Unii-OW44B6FA0Y 10mg $426 2021-12-16 Buy
American Custom Chemicals Corporation API0007699 (2E)-N-(1-ACETYL-2,3-DIHYDRO-1H-INDOL-6-YL)-3-(3-CYANOPHENYL)-N-[1-(2-CYCLOPENTYLETHYL)-4-PIPERIDINYL]-2-PROPENAMIDE 95.00% 10MG $782.23 2021-12-16 Buy
American Custom Chemicals Corporation API0007699 (2E)-N-(1-ACETYL-2,3-DIHYDRO-1H-INDOL-6-YL)-3-(3-CYANOPHENYL)-N-[1-(2-CYCLOPENTYLETHYL)-4-PIPERIDINYL]-2-PROPENAMIDE 95.00% 50MG $1546.26 2021-12-16 Buy
ApexBio Technology B5512 JNJ5207787 10mg $434 2021-12-16 Buy
ApexBio Technology B5512 JNJ5207787 50mg $1708 2021-12-16 Buy
Cayman Chemical 13947 JNJ-5207787 ≥98% 1mg $44 2024-03-01 Buy
Cayman Chemical 13947 JNJ-5207787 ≥98% 5mg $163 2024-03-01 Buy
Cayman Chemical 13947 JNJ-5207787 ≥98% 10mg $296 2024-03-01 Buy
Cayman Chemical 13947 JNJ-5207787 ≥98% 50mg $1184 2024-03-01 Buy
Tocris 4018 JNJ5207787 ≥98%(HPLC) 10 $293 2021-12-16 Buy
TRC J211383 JNJ5207787 50mg $1080 2021-12-16 Buy

Properties

Density :1.22
storage temp. :Store at RT
solubility :Soluble to 10 mM in DMSO with gentle warming and to 10 mM in ethanol with gentle warming
form :Powder

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

JNJ-5207787 is an antagonist of the neuropeptide Y (NPY) receptor Y2 that blocks peptide YY binding (IC50 = 100 nM). It displays 100-fold selectivity for Y2 over other NPY receptors and has minimal effect on a panel of 50 receptors, ion channels, and transporters, except for sodium channel 2. JNJ-5207787 is intraperitoneally bioavailable and brain penetrant in rats, occupying maximally 50% of Y2 receptor binding sites in the hypothalamic area.