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ChemicalBook >> CAS DataBase List >> N-(6-Fluoro-1H-indazol-5-yl)-2-methyl-6-oxo-4-[4-(trifluoromethyl)phenyl]-1,4,5,6-tetrahydro-3-pyridinecarboxamide

N-(6-Fluoro-1H-indazol-5-yl)-2-methyl-6-oxo-4-[4-(trifluoromethyl)phenyl]-1,4,5,6-tetrahydro-3-pyridinecarboxamide

N-(6-Fluoro-1H-indazol-5-yl)-2-methyl-6-oxo-4-[4-(trifluoromethyl)phenyl]-1,4,5,6-tetrahydro-3-pyridinecarboxamide price.
  • $29 - $5935
  • Product name: N-(6-Fluoro-1H-indazol-5-yl)-2-methyl-6-oxo-4-[4-(trifluoromethyl)phenyl]-1,4,5,6-tetrahydro-3-pyridinecarboxamide
  • CAS: 864082-47-3
  • MF: C21H16F4N4O2
  • MW: 432.37
  • EINECS:
  • MDL Number:MFCD16618404
  • Synonyms:RHO-15(GSK429286A);GSK 429286 A;RHO-15;N-(6-fluoro-1H-indazol-5-yl)-2-methyl-6-oxo-4-(4-(trifluoromethyl)phenyl)-1,4,5,6-tetrahydropyridine-3-carboxamide;GSK 429286 A N-(6-Fluoro-1H-indazol-5-yl)-2-methyl-6-oxo-4-[4-(trifluoromethyl)phenyl]-1,4,5,6-tetrahydro-3-pyridinecarboxamide;N-(6-Fluoro-1H-indazol-5-yl)-2-methyl-6-oxo-4-[4-(trifluoromethyl)phenyl]-1,4,5,6-tetrahydro-3-pyridinecarboxamide GSK 429286 A;N-(6-Fluoro-1H-indazol-5-yl)-1,4,5,6-tetrahydro-2-methyl-6-oxo-4-[4-(trifluoromethyl)phenyl]-3-pyridinecarboxamide;N-(6-Fluoro-1H-indazol-5-yl)-2-methyl-6-oxo-4-[4-(trifluoromethyl)phenyl]-1,4,5,6-tetrahydro-3-pyridinecarboxamide
Price55 Properties Safety Information Description
55 prices
Selected condition：
Brand
  • aablocks
  • ACHEMBLOCK
  • Adipogen Life Sciences
  • AK Scientific
  • Ambeed
  • ApexBio Technology
  • Arctom
  • Biorbyt Ltd
  • Biosynth
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Matrix Scientific
Package
  • 1000mg
  • 1g
  • 10mM*1mLinDMSO(Solid+Solvent)
  • 10mM*1mLinDMSO(Solution)
  • 10mM*1mLinDMSO
  • 2.00g
  • 5.00g
  • 5g
  • 10.00g
  • 1mg
  • 5mg
  • 10mM(in1mLDMSO)
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250MG
  • 10mM(in 1mL DMSO)
  • Manufactureraablocks
  • Product numberAA00GRS2
  • Product descriptionGSK429286A ≥98%
  • Packaging25mg
  • Price$112
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00GRS2
  • Product descriptionGSK429286A 98%
  • Packaging50mg
  • Price$166
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00GRS2
  • Product descriptionGSK429286A 98%
  • Packaging100mg
  • Price$288
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00GRS2
  • Product descriptionGSK429286A ≥98%
  • Packaging10mg
  • Price$51
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00GRS2
  • Product descriptionGSK429286A ≥98%
  • Packaging5mg
  • Price$29
  • Updated2026-05-28
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberP50917
  • Product descriptionGSK 429286A 98%
  • Packaging100MG
  • Price$280
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberP50917
  • Product descriptionGSK 429286A 98%
  • Packaging250MG
  • Price$560
  • Updated2026-05-27
  • Buy
  • ManufacturerAdipogen Life Sciences
  • Product numberSYN-1071-M010
  • Product descriptionGSK429286A ≥95%
  • Packaging10mg
  • Price$248
  • Updated2026-05-06
  • Buy
  • ManufacturerAdipogen Life Sciences
  • Product numberSYN-1071-M005
  • Product descriptionGSK429286A ≥95%
  • Packaging5mg
  • Price$167
  • Updated2026-05-06
  • Buy
  • ManufacturerAdipogen Life Sciences
  • Product numberSYN-1071-M001
  • Product descriptionGSK429286A ≥95%
  • Packaging1mg
  • Price$97
  • Updated2026-05-06
  • Buy
  • ManufacturerAdipogen Life Sciences
  • Product numberSYN-1071-M050
  • Product descriptionGSK429286A ≥95%
  • Packaging50mg
  • Price$718
  • Updated2026-05-06
  • Buy
  • ManufacturerAK Scientific
  • Product numberSYN1071
  • Product descriptionGSK429286A
  • Packaging50mg
  • Price$685
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberSYN1071
  • Product descriptionGSK429286A
  • Packaging1mg
  • Price$110
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA569516
  • Product descriptionGSK429286A 98+%
  • Packaging5mg
  • Price$178
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA569516
  • Product descriptionGSK429286A 98+%
  • Packaging1mg
  • Price$59
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA569516
  • Product descriptionGSK429286A 98+%
  • Packaging25mg
  • Price$300
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA00GRS2 GSK429286A ≥98% 25mg $112 2026-05-28 Buy
aablocks AA00GRS2 GSK429286A 98% 50mg $166 2026-05-28 Buy
aablocks AA00GRS2 GSK429286A 98% 100mg $288 2026-05-28 Buy
aablocks AA00GRS2 GSK429286A ≥98% 10mg $51 2026-05-28 Buy
aablocks AA00GRS2 GSK429286A ≥98% 5mg $29 2026-05-28 Buy
ACHEMBLOCK P50917 GSK 429286A 98% 100MG $280 2026-05-27 Buy
ACHEMBLOCK P50917 GSK 429286A 98% 250MG $560 2026-05-27 Buy
Adipogen Life Sciences SYN-1071-M010 GSK429286A ≥95% 10mg $248 2026-05-06 Buy
Adipogen Life Sciences SYN-1071-M005 GSK429286A ≥95% 5mg $167 2026-05-06 Buy
Adipogen Life Sciences SYN-1071-M001 GSK429286A ≥95% 1mg $97 2026-05-06 Buy
Adipogen Life Sciences SYN-1071-M050 GSK429286A ≥95% 50mg $718 2026-05-06 Buy
AK Scientific SYN1071 GSK429286A 50mg $685 2021-12-16 Buy
AK Scientific SYN1071 GSK429286A 1mg $110 2021-12-16 Buy
Ambeed A569516 GSK429286A 98+% 5mg $178 2021-12-16 Buy
Ambeed A569516 GSK429286A 98+% 1mg $59 2021-12-16 Buy
Ambeed A569516 GSK429286A 98+% 25mg $300 2021-12-16 Buy
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Properties

Boiling point :688.4±55.0 °C(Predicted)
Density :1.468
storage temp. :Sealed in dry,2-8°C
solubility :DMSO: ≥10mg/mL
pka :12.10±0.40(Predicted)
form :powder
color :white to beige
InChIKey :OLIIUAHHAZEXEX-UHFFFAOYSA-N
SMILES :C1(C)NC(=O)CC(C2=CC=C(C(F)(F)F)C=C2)C=1C(NC1C(F)=CC2=C(C=1)C=NN2)=O
CAS DataBase Reference :864082-47-3

Safety Information

Symbol(GHS): Skull and Crossbones (GHS06)
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H301 Toxic if swalloed Acute toxicity,oral Category 3 Danger P264, P270, P301+P310, P321, P330,P405, P501
Precautionary statements:
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

Description

GSK429286A is a cell-permeable inhibitor of Rho-associated kinase (IC50 = 14 nM). It less potently inhibits p90 and p70 ribosomal S6 kinases (IC50s = 780 and 1,940 nM, respectively) and is ineffective against leucine-rich repeat protein kinase-2. GSK429286A reverses adrenalin-induced contraction of rat aortic rings (IC50 = 190 nM) and produces a dose-dependent decrease in mean arterial pressure in spontaneously-hypertensive rats.

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Suppliers and manufacturers

Wuhan Yingnuo Pharmaceutical Technology Co., Ltd. Shanghai Beckham Medical Technology Co., Ltd Shanghai Boyle Chemical Co., Ltd. 3B Pharmachem (Wuhan) International Co.,Ltd. Chembest Research Laboratories Limited Jinan Trio PharmaTech Co., Ltd. Xi’an chemsoar Medical Technology Co., ltd China Langchem Inc. BOC Sciences Dalian Meilun Biotech Co., Ltd.