DIACYLGLYCEROL KINASE INHIBITOR I
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- $37 - $1138.78
- Product name: DIACYLGLYCEROL KINASE INHIBITOR I
- CAS: 93076-89-2
- MF: C27H26FN3OS
- MW: 459.58
- EINECS:
- MDL Number:MFCD00055114
- Synonyms:DIACYLGLYCEROL KINASE;DIACYLGLYCEROL KINASE INHIBITOR I;DIACYLGLYCEROL KINASE INHIBITOR I (R59 022);DAGK;DAG KINASE;EC 2.7.1.107;EC: 2.7.1.107;DKI
20 prices
Selected condition：
Brand
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Cayman Chemical
- ChemScene
- Medical Isotopes, Inc.
- Sigma-Aldrich
- Tocris
- TRC
- Usbiological
Package
- 50
- 1MG
- 5mg
- 10MG
- 10
- 50mg
- ManufacturerAK Scientific
- Product number0350CA
- Product descriptionDiacylglycerol Kinase Inhibitor I
- Packaging50mg
- Price$843
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0000210
- Product descriptionR-59-022 95.00%
- Packaging1MG
- Price$140.7
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0000210
- Product descriptionR-59-022 95.00%
- Packaging10MG
- Price$685.21
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0000210
- Product descriptionR-59-022 95.00%
- Packaging50MG
- Price$1138.78
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB6967
- Product descriptionR59-022
- Packaging5mg
- Price$102
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number16772
- Product descriptionR-59-022 ≥98%
- Packaging1mg
- Price$37
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number16772
- Product descriptionR-59-022 ≥98%
- Packaging5mg
- Price$90
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number16772
- Product descriptionR-59-022 ≥98%
- Packaging10mg
- Price$157
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number16772
- Product descriptionR-59-022 ≥98%
- Packaging50mg
- Price$670
- Updated2024-03-01
- Buy
- ManufacturerChemScene
- Product numberCS-0028966
- Product descriptionR59-022 >99.0%
- Packaging5mg
- Price$350
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0028966
- Product descriptionR59-022 >99.0%
- Packaging10mg
- Price$550
- Updated2021-12-16
- Buy
- ManufacturerMedical Isotopes, Inc.
- Product number72241
- Product descriptionR-59-022(DiacylglycerolKinaseInhibitorI)
- Packaging50mg
- Price$940
- Updated2021-12-16
- Buy
- ManufacturerSigma-Aldrich
- Product numberD5919
- Product descriptionDiacylglycerol Kinase Inhibitor I solid
- Packaging1mg
- Price$131
- Updated2025-07-31
- Buy
- ManufacturerSigma-Aldrich
- Product number266785
- Product descriptionDiacylglycerol Kinase Inhibitor I
- Packaging5mg
- Price$177
- Updated2025-07-31
- Buy
- ManufacturerSigma-Aldrich
- Product numberD5919
- Product descriptionDiacylglycerol Kinase Inhibitor I solid
- Packaging5mg
- Price$452
- Updated2025-07-31
- Buy
- ManufacturerTocris
- Product number2194
- Product descriptionR59-022 ≥98%(HPLC)
- Packaging10
- Price$162
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 0350CA | Diacylglycerol Kinase Inhibitor I | 50mg | $843 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | KIN0000210 | R-59-022 95.00% | 1MG | $140.7 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | KIN0000210 | R-59-022 95.00% | 10MG | $685.21 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | KIN0000210 | R-59-022 95.00% | 50MG | $1138.78 | 2021-12-16 | Buy |
| ApexBio Technology | B6967 | R59-022 | 5mg | $102 | 2021-12-16 | Buy |
| Cayman Chemical | 16772 | R-59-022 ≥98% | 1mg | $37 | 2024-03-01 | Buy |
| Cayman Chemical | 16772 | R-59-022 ≥98% | 5mg | $90 | 2024-03-01 | Buy |
| Cayman Chemical | 16772 | R-59-022 ≥98% | 10mg | $157 | 2024-03-01 | Buy |
| Cayman Chemical | 16772 | R-59-022 ≥98% | 50mg | $670 | 2024-03-01 | Buy |
| ChemScene | CS-0028966 | R59-022 >99.0% | 5mg | $350 | 2021-12-16 | Buy |
| ChemScene | CS-0028966 | R59-022 >99.0% | 10mg | $550 | 2021-12-16 | Buy |
| Medical Isotopes, Inc. | 72241 | R-59-022(DiacylglycerolKinaseInhibitorI) | 50mg | $940 | 2021-12-16 | Buy |
| Sigma-Aldrich | D5919 | Diacylglycerol Kinase Inhibitor I solid | 1mg | $131 | 2025-07-31 | Buy |
| Sigma-Aldrich | 266785 | Diacylglycerol Kinase Inhibitor I | 5mg | $177 | 2025-07-31 | Buy |
| Sigma-Aldrich | D5919 | Diacylglycerol Kinase Inhibitor I solid | 5mg | $452 | 2025-07-31 | Buy |
| Tocris | 2194 | R59-022 ≥98%(HPLC) | 10 | $162 | 2021-12-16 | Buy |
Properties
Boiling point :619.8±65.0 °C(Predicted)
Density :1.26±0.1 g/cm3(Predicted)
storage temp. :-20°C
solubility :0.1 M HCl: slightly soluble
form :solid
pka :7.76±0.20(Predicted)
color :pale yellow
biological source :synthetic (organic)
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
Density :1.26±0.1 g/cm3(Predicted)
storage temp. :-20°C
solubility :0.1 M HCl: slightly soluble
form :solid
pka :7.76±0.20(Predicted)
color :pale yellow
biological source :synthetic (organic)
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
Safety Information
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Description
Diacylglycerol (DAG) kinases (DGKs) phosphorylate DAG to give phosphatidic acid (PA), reducing signaling through DAG and increasing signaling through PA. R-59-022 is an inhibitor of DGK (IC50 = 2.8 μM). This results in increased DAG-dependent PKC activity and potentiates aggregation of thrombin-stimulated platelets. R-59-022 also blocks vascular contraction induced by the thromboxane analog U-46619 . At 10 μM, R-59-022 induces apoptosis in glioblastoma cells without being toxic to non-cancerous cells. It inhibits DGK-θ in vitro at concentrations below 1 μM and blocks DGK-θ activity in vivo. R-59-022 also inhibits A. thaliana DGK2 (IC50 = 50 μM) and suppresses root growth but does not affect DGK7 at 50 μM.Related product price
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Suppliers and manufacturers
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Sigma-Aldrich
EMMX Biotechnology LLC
