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ChemicalBook >> CAS DataBase List >> BKM120 (NVP-BKM120, Buparlisib)

BKM120 (NVP-BKM120, Buparlisib)

BKM120 (NVP-BKM120, Buparlisib) price.
  • $19 - $4200
  • Product name: BKM120 (NVP-BKM120, Buparlisib)
  • CAS: 944396-07-0
  • MF: C18H21F3N6O2
  • MW: 410.39
  • EINECS:
  • MDL Number:MFCD18251596
  • Synonyms:5-[2,6-Di(4-morpholinyl)-4-pyrimidinyl]-4-(trifluoromethyl)-2-pyridinamine;BKM120 (NVP-BKM120);NVP-BKM-120;BKM120 (NVP-BKM120, Buparlisib);NVP-BKM120, Buparlisib;BKM120BASE;BKM-120 4-(2,6-diMorpholinopyriMidin-4-yl)-3-(trifluoroMethyl)aniline;5-[2,6-Di(4-morpholinyl)-4-pyrimidinyl]-4-(trifluoromethyl)-2-pyridinamine BKM120 (NVP-BKM120, Buparlisib)
Price69 Properties Safety Information Description
69 prices
Selected condition：
Brand
  • aablocks
  • ACHEMBLOCK
  • Adipogen Life Sciences
  • ApexBio Technology
  • Arctom
  • AvaChem
  • Axon Medchem
  • Biorbyt Ltd
  • Biosynth
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Matrix Scientific
  • Medical Isotopes, Inc.
  • TRC
Package
  • 10mM*1mLinDMSO(Solution)
  • 2x25mg
  • 1unit
  • 10mM*1mLinDMSO(Solid+Solvent)
  • 200mg
  • 500mg
  • 50.00g
  • 250.00g
  • 10mM*1mLinDMSO
  • 100.00g
  • 1mg
  • 10mM(in1mLDMSO)
  • 5mg
  • 10mg
  • 25MG
  • 50mg
  • 100mg
  • 1G
  • EvaluationSample
  • 250mg
  • Manufactureraablocks
  • Product numberAA0036M4
  • Product description5-(2,6-Di-4-morpholinyl-4-pyrimidinyl)-4-(trifluoromethyl)-2-pyridinamine 98%
  • Packaging1mg
  • Price$19
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA0036M4
  • Product description5-(2,6-Di-4-morpholinyl-4-pyrimidinyl)-4-(trifluoromethyl)-2-pyridinamine ≥95%
  • Packaging5mg
  • Price$29
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA0036M4
  • Product description5-(2,6-Di-4-morpholinyl-4-pyrimidinyl)-4-(trifluoromethyl)-2-pyridinamine 98%
  • Packaging10mg
  • Price$37
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA0036M4
  • Product description5-(2,6-Di-4-morpholinyl-4-pyrimidinyl)-4-(trifluoromethyl)-2-pyridinamine 98%
  • Packaging50mg
  • Price$47
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA0036M4
  • Product description5-(2,6-Di-4-morpholinyl-4-pyrimidinyl)-4-(trifluoromethyl)-2-pyridinamine 98%
  • Packaging250mg
  • Price$144
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA0036M4
  • Product description5-(2,6-Di-4-morpholinyl-4-pyrimidinyl)-4-(trifluoromethyl)-2-pyridinamine 98%
  • Packaging100mg
  • Price$73
  • Updated2026-05-28
  • Buy
  • ManufacturerACHEMBLOCK
  • Product number10296
  • Product descriptionBKM120 98%
  • Packaging25MG
  • Price$32
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product number10296
  • Product descriptionBKM120 98%
  • Packaging100MG
  • Price$77
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product number10296
  • Product descriptionBKM120 98%
  • Packaging1G
  • Price$261
  • Updated2026-05-27
  • Buy
  • ManufacturerAdipogen Life Sciences
  • Product numberSYN-1200-M050
  • Product descriptionBKM120 ≥95%
  • Packaging50mg
  • Price$421
  • Updated2026-05-06
  • Buy
  • ManufacturerAdipogen Life Sciences
  • Product numberSYN-1200-M100
  • Product descriptionBKM120 ≥95%
  • Packaging100mg
  • Price$702
  • Updated2026-05-06
  • Buy
  • ManufacturerAdipogen Life Sciences
  • Product numberSYN-1200-M001
  • Product descriptionBKM120 ≥95%
  • Packaging1mg
  • Price$65
  • Updated2026-05-06
  • Buy
  • ManufacturerAdipogen Life Sciences
  • Product numberSYN-1200-M005
  • Product descriptionBKM120 ≥95%
  • Packaging5mg
  • Price$97
  • Updated2026-05-06
  • Buy
  • ManufacturerAdipogen Life Sciences
  • Product numberSYN-1200-M010
  • Product descriptionBKM120 ≥95%
  • Packaging10mg
  • Price$130
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA3015
  • Product descriptionBKM120
  • Packaging10mg
  • Price$119
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA3015
  • Product descriptionBKM120
  • Packaging5mg
  • Price$79
  • Updated2026-05-06
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA0036M4 5-(2,6-Di-4-morpholinyl-4-pyrimidinyl)-4-(trifluoromethyl)-2-pyridinamine 98% 1mg $19 2026-05-28 Buy
aablocks AA0036M4 5-(2,6-Di-4-morpholinyl-4-pyrimidinyl)-4-(trifluoromethyl)-2-pyridinamine ≥95% 5mg $29 2026-05-28 Buy
aablocks AA0036M4 5-(2,6-Di-4-morpholinyl-4-pyrimidinyl)-4-(trifluoromethyl)-2-pyridinamine 98% 10mg $37 2026-05-28 Buy
aablocks AA0036M4 5-(2,6-Di-4-morpholinyl-4-pyrimidinyl)-4-(trifluoromethyl)-2-pyridinamine 98% 50mg $47 2026-05-28 Buy
aablocks AA0036M4 5-(2,6-Di-4-morpholinyl-4-pyrimidinyl)-4-(trifluoromethyl)-2-pyridinamine 98% 250mg $144 2026-05-28 Buy
aablocks AA0036M4 5-(2,6-Di-4-morpholinyl-4-pyrimidinyl)-4-(trifluoromethyl)-2-pyridinamine 98% 100mg $73 2026-05-28 Buy
ACHEMBLOCK 10296 BKM120 98% 25MG $32 2026-05-27 Buy
ACHEMBLOCK 10296 BKM120 98% 100MG $77 2026-05-27 Buy
ACHEMBLOCK 10296 BKM120 98% 1G $261 2026-05-27 Buy
Adipogen Life Sciences SYN-1200-M050 BKM120 ≥95% 50mg $421 2026-05-06 Buy
Adipogen Life Sciences SYN-1200-M100 BKM120 ≥95% 100mg $702 2026-05-06 Buy
Adipogen Life Sciences SYN-1200-M001 BKM120 ≥95% 1mg $65 2026-05-06 Buy
Adipogen Life Sciences SYN-1200-M005 BKM120 ≥95% 5mg $97 2026-05-06 Buy
Adipogen Life Sciences SYN-1200-M010 BKM120 ≥95% 10mg $130 2026-05-06 Buy
ApexBio Technology A3015 BKM120 10mg $119 2026-05-06 Buy
ApexBio Technology A3015 BKM120 5mg $79 2026-05-06 Buy
Next Last

Properties

Melting point :143-147°C
Boiling point :645.7±65.0 °C(Predicted)
Density :1.382
storage temp. :-20°C
solubility :Soluble in DMSO (15 mg/ml)
form :White powder.
pka :5.94±0.50(Predicted)
color :White
Stability :Stable for 1 year as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.

Safety Information

Symbol(GHS): Health Hazard (GHS08)Skull and Crossbones (GHS06)
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H301 Toxic if swalloed Acute toxicity,oral Category 3 Danger P264, P270, P301+P310, P321, P330,P405, P501
H341 Suspected of causing genetic defects Germ cell mutagenicity Category 2 Warning P201,P202, P281, P308+P313, P405,P501
H372 Causes damage to organs through prolonged or repeated exposure Specific target organ toxicity, repeated exposure Category 1 Danger P260, P264, P270, P314, P501
Precautionary statements:
P201 Obtain special instructions before use.
P202 Do not handle until all safety precautions have been read and understood.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P281 Use personal protective equipment as required.
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P308+P313 IF exposed or concerned: Get medical advice/attention.
P314 Get medical advice/attention if you feel unwell.
P321 Specific treatment (see … on this label).
P330 Rinse mouth.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

Phosphatidylinositol 3-kinases (PI3K) belong to a family of lipid kinases that is involved in many types of cancer. NVP-BKM120 is an orally bioavailable inhibitor of class I PI3K isoforms, potently blocking, in vitro, both p110α (IC50 = 52 nM) and p110β (IC50 = 166 nM). It much less effectively inhibits the class III PI3K Vps34 and mammalian target of rapamycin and has no effect on PI4Kβ and several other kinases. NVP-BKM120 prevents the growth of assorted cancer cell lines when used at 5 μM and inhibits tumor growth in vivo. It can be particularly effective against certain types of cancer when combined with other modulators.

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Suppliers and manufacturers

Shanghai Boyle Chemical Co., Ltd. J & K SCIENTIFIC LTD. Chembest Research Laboratories Limited Jia Xing Isenchem Co.,Ltd Nanjing Chemlin Chemical Co., Ltd China DongFan Chemical Co.,LTD Jinan Trio PharmaTech Co., Ltd. Nanjing Vital Chemical Co., Ltd. Dalian Meilun Biotech Co., Ltd. Shanghai Hope Chem Co., Ltd.，