A23187
|
- $43 - $2655
- Product name: A23187
- CAS: 52665-69-7
- MF: C29H37N3O6
- MW: 523.62
- EINECS:258-084-1
- MDL Number:MFCD00151202
- Synonyms:A 23187, CaliMycin;CalciuM Ionophore A23187, froM StreptoMyces chartreusis;Calcimycin [Calcium Ionophore A23187];4-Benzoxazolecarboxylicacid,5-(methylamino)-2-[[(2R,3R,6S,8S,9R,11R)-3,9,11-trimethyl-8-[(1S)-1-methyl-2-oxo-2-(1H-pyrrol-2-yl)ethyl]-1,7-dioxaspiro[5.5]undec-2-yl]methyl]-;4-BENZOXAZOLECARBOXYLIC ACID, 5-(METHYLAMINO)-2-((3,9,11-TRIMETHYL-8-(1-METHYL-2-OXO-2-(1H-PYRROL-2-YL)ETHYL)-1,7-DIOXASPIRO(5.5)UNDEC-2-YL)METHYL)-(6S-(6ALPHA(2S*,3S*),8BETA(R),9BETA,11ALPHA))-;5-(METHYLAMINO)-2-[[[2R,3R,6S,8S,9R,11R]-3,9,11-TRIMETHYL-8-[(1S)-1-METHYL-2-OXO-2-(1H-PYRROL-2-YL)-ETHYL]-1,7-DIOXASPIRO[5.5]UNDEC-2-YL]METHYL]-4-BENZOXAZOLECARBOXYLIC ACID;A23187;ANTIBIOTIC A23187
54 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- ApexBio Technology
- Apolloscientific
- Arctom
- AvaChem
- Biosynth
- Cayman Chemical
- ChemScene
- Sigma-Aldrich
- Thermo Scientific Chemicals
- TRC
- Usbiological
Package
- 10mM*1mLinDMSO(Solid+Solvent)
- 1mg
- 2mg
- 5mg
- 10mg
- 10mM*1mLinDMSO(Solution)
- 25mg
- 50mg
- 100MG
- 250mg
- 10 mg
- Manufactureraablocks
- Product numberAA00D7U6
- Product description5-(Methylamino)-2-[[(2R,3R,6S,8S,9R,11R)-3,9,11-trimethyl-8-[(1S)-1-methyl-2-oxo-2-(1H-pyrrol-2-yl)ethyl]-1,7-dioxaspiro[5.5]undec-2-yl]methyl]-4-benzoxazolecarboxylic acid ≥98%
- Packaging1mg
- Price$43
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00D7U6
- Product description5-(Methylamino)-2-[[(2R,3R,6S,8S,9R,11R)-3,9,11-trimethyl-8-[(1S)-1-methyl-2-oxo-2-(1H-pyrrol-2-yl)ethyl]-1,7-dioxaspiro[5.5]undec-2-yl]methyl]-4-benzoxazolecarboxylic acid ≥98%
- Packaging5mg
- Price$86
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00D7U6
- Product description5-(Methylamino)-2-[[(2R,3R,6S,8S,9R,11R)-3,9,11-trimethyl-8-[(1S)-1-methyl-2-oxo-2-(1H-pyrrol-2-yl)ethyl]-1,7-dioxaspiro[5.5]undec-2-yl]methyl]-4-benzoxazolecarboxylic acid ≥98%
- Packaging10mg
- Price$151
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00D7U6
- Product description5-(Methylamino)-2-[[(2R,3R,6S,8S,9R,11R)-3,9,11-trimethyl-8-[(1S)-1-methyl-2-oxo-2-(1H-pyrrol-2-yl)ethyl]-1,7-dioxaspiro[5.5]undec-2-yl]methyl]-4-benzoxazolecarboxylic acid ≥98%
- Packaging25mg
- Price$269
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberY225934
- Product descriptionCalcimycin 97.00%
- Packaging5MG
- Price$235
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberY225934
- Product descriptionCalcimycin 97.00%
- Packaging25MG
- Price$885
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberY225934
- Product descriptionCalcimycin 97.00%
- Packaging100MG
- Price$2655
- Updated2026-05-27
- Buy
- ManufacturerApexBio Technology
- Product numberB6646
- Product descriptionA23187, free acid
- Packaging10mg
- Price$312
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberB6646
- Product descriptionA23187, free acid
- Packaging25mg
- Price$430
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberB6646
- Product descriptionA23187, free acid
- Packaging5mg
- Price$198
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberB6646
- Product descriptionA23187, free acid
- Packaging1mg
- Price$95
- Updated2026-05-06
- Buy
- ManufacturerApolloscientific
- Product numberBIC1006
- Product descriptionCalcimycin A23187
- Packaging5mg
- Price$97
- Updated2026-06-04
- Buy
- ManufacturerApolloscientific
- Product numberBIC1006
- Product descriptionCalcimycinA23187
- Packaging1mg
- Price$72
- Updated2021-12-16
- Buy
- ManufacturerApolloscientific
- Product numberBIC1006
- Product descriptionCalcimycin A23187
- Packaging10mg
- Price$170
- Updated2026-06-04
- Buy
- ManufacturerApolloscientific
- Product numberBIC1006
- Product descriptionCalcimycin A23187
- Packaging50mg
- Price$667
- Updated2026-06-04
- Buy
- ManufacturerApolloscientific
- Product numberBIC1006
- Product descriptionCalcimycin A23187
- Packaging25mg
- Price$373
- Updated2026-06-04
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA00D7U6 | 5-(Methylamino)-2-[[(2R,3R,6S,8S,9R,11R)-3,9,11-trimethyl-8-[(1S)-1-methyl-2-oxo-2-(1H-pyrrol-2-yl)ethyl]-1,7-dioxaspiro[5.5]undec-2-yl]methyl]-4-benzoxazolecarboxylic acid ≥98% | 1mg | $43 | 2026-05-28 | Buy |
| aablocks | AA00D7U6 | 5-(Methylamino)-2-[[(2R,3R,6S,8S,9R,11R)-3,9,11-trimethyl-8-[(1S)-1-methyl-2-oxo-2-(1H-pyrrol-2-yl)ethyl]-1,7-dioxaspiro[5.5]undec-2-yl]methyl]-4-benzoxazolecarboxylic acid ≥98% | 5mg | $86 | 2026-05-28 | Buy |
| aablocks | AA00D7U6 | 5-(Methylamino)-2-[[(2R,3R,6S,8S,9R,11R)-3,9,11-trimethyl-8-[(1S)-1-methyl-2-oxo-2-(1H-pyrrol-2-yl)ethyl]-1,7-dioxaspiro[5.5]undec-2-yl]methyl]-4-benzoxazolecarboxylic acid ≥98% | 10mg | $151 | 2026-05-28 | Buy |
| aablocks | AA00D7U6 | 5-(Methylamino)-2-[[(2R,3R,6S,8S,9R,11R)-3,9,11-trimethyl-8-[(1S)-1-methyl-2-oxo-2-(1H-pyrrol-2-yl)ethyl]-1,7-dioxaspiro[5.5]undec-2-yl]methyl]-4-benzoxazolecarboxylic acid ≥98% | 25mg | $269 | 2026-05-28 | Buy |
| ACHEMBLOCK | Y225934 | Calcimycin 97.00% | 5MG | $235 | 2026-05-27 | Buy |
| ACHEMBLOCK | Y225934 | Calcimycin 97.00% | 25MG | $885 | 2026-05-27 | Buy |
| ACHEMBLOCK | Y225934 | Calcimycin 97.00% | 100MG | $2655 | 2026-05-27 | Buy |
| ApexBio Technology | B6646 | A23187, free acid | 10mg | $312 | 2026-05-06 | Buy |
| ApexBio Technology | B6646 | A23187, free acid | 25mg | $430 | 2026-05-06 | Buy |
| ApexBio Technology | B6646 | A23187, free acid | 5mg | $198 | 2026-05-06 | Buy |
| ApexBio Technology | B6646 | A23187, free acid | 1mg | $95 | 2026-05-06 | Buy |
| Apolloscientific | BIC1006 | Calcimycin A23187 | 5mg | $97 | 2026-06-04 | Buy |
| Apolloscientific | BIC1006 | CalcimycinA23187 | 1mg | $72 | 2021-12-16 | Buy |
| Apolloscientific | BIC1006 | Calcimycin A23187 | 10mg | $170 | 2026-06-04 | Buy |
| Apolloscientific | BIC1006 | Calcimycin A23187 | 50mg | $667 | 2026-06-04 | Buy |
| Apolloscientific | BIC1006 | Calcimycin A23187 | 25mg | $373 | 2026-06-04 | Buy |
Properties
Melting point :187-190 °C
alpha :D25 -56° (c = 1 in chloroform)
Boiling point :710.3±55.0 °C(Predicted)
Density :1.28±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :Soluble in DMSO with warming or sonication. Also soluble in ethanol or ethyl acetate
form :Solid
pka :pKa1 6.9 in 90% DMSO
color :white to light yellow
Merck :13,1639
BRN :1096801
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 4 months.
InChIKey :HIYAVKIYRIFSCZ-CYEMHPAKSA-N
SMILES :[H][C@@]1(O[C@@]2(CC[C@@H](C)[C@@H](Cc3nc4c(C(O)=O)c(NC)ccc4o3)O2)[C@H](C)C[C@H]1C)[C@H](C)C(=O)c5ccc[nH]5
alpha :D25 -56° (c = 1 in chloroform)
Boiling point :710.3±55.0 °C(Predicted)
Density :1.28±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :Soluble in DMSO with warming or sonication. Also soluble in ethanol or ethyl acetate
form :Solid
pka :pKa1 6.9 in 90% DMSO
color :white to light yellow
Merck :13,1639
BRN :1096801
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 4 months.
InChIKey :HIYAVKIYRIFSCZ-CYEMHPAKSA-N
SMILES :[H][C@@]1(O[C@@]2(CC[C@@H](C)[C@@H](Cc3nc4c(C(O)=O)c(NC)ccc4o3)O2)[C@H](C)C[C@H]1C)[C@H](C)C(=O)c5ccc[nH]5
Safety Information
| Symbol(GHS): |
|
|||||||||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Signal word: | Warning | |||||||||||||||||||||||||||||||||||
| Hazard statements: |
|
|||||||||||||||||||||||||||||||||||
| Precautionary statements: |
|
Description
A-23187 is a divalent cation ionophore. While more selective for Mn2+, it is commonly used to facilitate the movement of Ca2+ into cells, triggering the activation of intracellular calcium-dependent pathways. A-23187 is also used to produce apoptosis through calcium overload, as occurs during hypoxic or oxidative stress.Related product price
-
A23187
$43-2655 -
59450-89-4
$164-3157.5 -
Magnesium
$9.3-10280
Suppliers and manufacturers
Zhejiang Zhulong Biotechnology Co.,Ltd
J & K SCIENTIFIC LTD.
Meryer (Shanghai) Chemical Technology Co., Ltd.
3B Pharmachem (Wuhan) International Co.,Ltd.
Wuhan Chemwish Technology Co., Ltd
Ascent Scientific
Shanghai Sinch Parmaceuticals Tech. Co. Ltd.
Shandong Xiya Chemical Co., Ltd
Sinopharm Chemical Reagent Co,Ltd.
Thermo Fisher Scientific