Ac-DEVD-AFC
|
- $45 - $3390
- Product name: Ac-DEVD-AFC
- CAS: 201608-14-2
- MF: C30H34F3N5O13
- MW: 729.61
- EINECS:
- MDL Number:MFCD01310970
- Synonyms:N-ACETYL-ASP-GLU-VAL-ASP 7-AMIDO-4-TRIFLUOROMETHYLCOUMARIN;N-ACETYL-ASP-GLU-VAL-ASP-(7-AMINO-4-TRIFLUOROMETHYLCOUMARIN);N-ACETYL-ASP-GLU-VAL-ASP-7-AMINO-4-TRIFLUOROMETHYLCOUMARIN AFC;CASPASE 3 (APOPAIN) SUBSTRATE 1F, FLUOROGENIC;CASPASE-3 SUBSTRATE (AFC);CASPASE-3 SUBSTRATE VII, FLUOROGENIC;CASPASE-3 FLUOROGENIC SUBSTRATE;FLUOROGENIC CASPASE 3 SUBSTRATE AC-DEVD-AFC
27 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- American Custom Chemicals Corporation
- ApexBio Technology
- BroadPharm
- Cayman Chemical
- Chem-Impex
- ChemScene
- Sigma-Aldrich
- Thermo Scientific Chemicals
- TRC
Package
- 1mg
- 5mg
- 10mg
- 25mg
- 50mg
- 100MG
- 500MG
- Manufactureraablocks
- Product numberAA002DG9
- Product descriptionAc-DEVD-AFC ≥98%
- Packaging1mg
- Price$55
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA002DG9
- Product descriptionAc-DEVD-AFC
- Packaging5mg
- Price$138
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA002DG9
- Product descriptionAc-DEVD-AFC
- Packaging10mg
- Price$242
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA002DG9
- Product descriptionAc-DEVD-AFC
- Packaging50mg
- Price$560
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA002DG9
- Product descriptionAc-DEVD-AFC
- Packaging25mg
- Price$396
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberY229982
- Product descriptionAc-DEVD-AFC 97.00%
- Packaging25MG
- Price$560
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberY229982
- Product descriptionAc-DEVD-AFC 97.00%
- Packaging100MG
- Price$1130
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberY229982
- Product descriptionAc-DEVD-AFC 97.00%
- Packaging500MG
- Price$3390
- Updated2026-05-27
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberHCH0066705
- Product descriptionN-ACETYL-ASP-GLU-VAL-ASP-7-AMIDO-4-TRIFLUOROMETHYLCOUMARIN 95.00%
- Packaging25MG
- Price$1455.3
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberHCH0066705
- Product descriptionN-ACETYL-ASP-GLU-VAL-ASP-7-AMIDO-4-TRIFLUOROMETHYLCOUMARIN 95.00%
- Packaging1MG
- Price$154.35
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberC5524
- Product descriptionAc-DEVD-AFC
- Packaging1mg
- Price$81
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberC5524
- Product descriptionAc-DEVD-AFC
- Packaging5mg
- Price$244
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberC5524
- Product descriptionAc-DEVD-AFC
- Packaging10mg
- Price$447
- Updated2026-05-06
- Buy
- ManufacturerBroadPharm
- Product numberBP-23699
- Product descriptionAc-DEVD-AFC 98%
- Packaging10mg
- Price$336
- Updated2021-12-16
- Buy
- ManufacturerBroadPharm
- Product numberBP-23699
- Product descriptionAc-DEVD-AFC 98%
- Packaging25mg
- Price$670
- Updated2021-12-16
- Buy
- ManufacturerBroadPharm
- Product numberBP-23699
- Product descriptionAc-DEVD-AFC 98%
- Packaging50mg
- Price$1000
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA002DG9 | Ac-DEVD-AFC ≥98% | 1mg | $55 | 2026-05-28 | Buy |
| aablocks | AA002DG9 | Ac-DEVD-AFC | 5mg | $138 | 2026-05-28 | Buy |
| aablocks | AA002DG9 | Ac-DEVD-AFC | 10mg | $242 | 2026-05-28 | Buy |
| aablocks | AA002DG9 | Ac-DEVD-AFC | 50mg | $560 | 2026-05-28 | Buy |
| aablocks | AA002DG9 | Ac-DEVD-AFC | 25mg | $396 | 2026-05-28 | Buy |
| ACHEMBLOCK | Y229982 | Ac-DEVD-AFC 97.00% | 25MG | $560 | 2026-05-27 | Buy |
| ACHEMBLOCK | Y229982 | Ac-DEVD-AFC 97.00% | 100MG | $1130 | 2026-05-27 | Buy |
| ACHEMBLOCK | Y229982 | Ac-DEVD-AFC 97.00% | 500MG | $3390 | 2026-05-27 | Buy |
| American Custom Chemicals Corporation | HCH0066705 | N-ACETYL-ASP-GLU-VAL-ASP-7-AMIDO-4-TRIFLUOROMETHYLCOUMARIN 95.00% | 25MG | $1455.3 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | HCH0066705 | N-ACETYL-ASP-GLU-VAL-ASP-7-AMIDO-4-TRIFLUOROMETHYLCOUMARIN 95.00% | 1MG | $154.35 | 2021-12-16 | Buy |
| ApexBio Technology | C5524 | Ac-DEVD-AFC | 1mg | $81 | 2026-05-06 | Buy |
| ApexBio Technology | C5524 | Ac-DEVD-AFC | 5mg | $244 | 2026-05-06 | Buy |
| ApexBio Technology | C5524 | Ac-DEVD-AFC | 10mg | $447 | 2026-05-06 | Buy |
| BroadPharm | BP-23699 | Ac-DEVD-AFC 98% | 10mg | $336 | 2021-12-16 | Buy |
| BroadPharm | BP-23699 | Ac-DEVD-AFC 98% | 25mg | $670 | 2021-12-16 | Buy |
| BroadPharm | BP-23699 | Ac-DEVD-AFC 98% | 50mg | $1000 | 2021-12-16 | Buy |
Properties
Boiling point :1152.7±65.0 °C(Predicted)
Density :1.495±0.06 g/cm3(Predicted)
storage temp. :-20°C
solubility :H2O: 1 mg/mL
form :powder
pka :4.09±0.10(Predicted)
color :white
Water Solubility :H2O: 1mg/mL
Sequence :N-Acetyl-Asp-Glu-Val-Asp-7-amido-4-trifluoroMethylcoumarin
InChIKey :GZDRODOYEFEHGG-NUDCOPPTSA-N
SMILES :CC(C)[C@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(O)=O)NC(C)=O)C(=O)N[C@@H](CC(O)=O)C(=O)Nc1ccc2c(OC(=O)C=C2C(F)(F)F)c1
Density :1.495±0.06 g/cm3(Predicted)
storage temp. :-20°C
solubility :H2O: 1 mg/mL
form :powder
pka :4.09±0.10(Predicted)
color :white
Water Solubility :H2O: 1mg/mL
Sequence :N-Acetyl-Asp-Glu-Val-Asp-7-amido-4-trifluoroMethylcoumarin
InChIKey :GZDRODOYEFEHGG-NUDCOPPTSA-N
SMILES :CC(C)[C@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(O)=O)NC(C)=O)C(=O)N[C@@H](CC(O)=O)C(=O)Nc1ccc2c(OC(=O)C=C2C(F)(F)F)c1
Safety Information
| Symbol(GHS): | ||||||||
|---|---|---|---|---|---|---|---|---|
| Signal word: | ||||||||
| Hazard statements: |
|
|||||||
| Precautionary statements: |
|
Description
During apoptosis, activated caspase-3 cleaves several substrates, including poly(ADP-ribose) polymerase, which it specifically targets at the amino sequence DEVD. Ac-DEVD-AFC is a fluorogenic substrate for activated caspase-3 (Km = 9.7 μM), as well as related caspases. Caspase activity can be quantified by fluorescent detection of free AFC (also known as 7-amino-4-trifluoromethylcoumarin), which is excited at 400 nm and emits at 505 nm.Related product price
-
Z-VAD-FMK
$38-5672 -
PAC1
$9-2245.7 -
CASPASE INHIBITOR3
$52-1209.29
Suppliers and manufacturers
Zhongke Huayao (Jiangsu) Biotechnology Co., Ltd
3B Pharmachem (Wuhan) International Co.,Ltd.
GL Biochem (Shanghai) Ltd
Beijing Ouhe Technology Co., Ltd
VDM Biochemicals
Shanghai Hanhong Scientific Co.,Ltd.
Chemsky（shanghai）International Co.,Ltd.
TargetMol Chemicals Inc.
Sigma-Aldrich
Creative Peptides