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ChemicalBook >> CAS DataBase List >> ALPHA-AMANITIN

ALPHA-AMANITIN

$177 - $11422.5
Product name: ALPHA-AMANITIN
CAS: 23109-05-9
MF: C39H54N10O14S
MW: 918.98
EINECS:245-432-2
MDL Number:MFCD30207890
Synonyms:Aids004473;Aids-004473;AMANITIN, a-(RG);AMANITIN, a-(RG)(CALL);cyclo[L-Asparaginyl-4-hydroxy-L-proly-(R-4,5-dihydroxy-L-isoleucyl-6-hydroxy-2-mercapto-L-tryptophylglycyl-L-isoleucylglycyl-L-cysteinyl]cyclic(4-8)-sulfide(R)-S-oxide;alpha-AMantine, froM AManita Phalloides;AMANITIN, A-;ALPHA-AMANITIN

Price50 Properties Safety Information Description

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Brand

aablocks
AK Scientific
American Custom Chemicals Corporation
ApexBio Technology
Apolloscientific
Arctom
Biorbyt Ltd
Biosynth
Cayman Chemical
ChemScene
Crysdot
DC Chemicals
Sigma-Aldrich
Tocris
Usbiological

Package

100μg
500μg
1mg
2mg
5MG
1
10mg
25mg
50mg
100mg
250mg
1g

Manufactureraablocks
Product numberAA00BBRV
Product descriptionα-Amanitin ≥90%
Packaging1mg
Price$274
Updated2026-05-28
Buy

ManufacturerAK Scientific
Product numberX9108
Product descriptionAlpha-Amanitin
Packaging1mg
Price$336
Updated2021-12-16
Buy

ManufacturerAmerican Custom Chemicals Corporation
Product numberPEP0009352
Product descriptionALPHA-AMANITIN 95.00%
Packaging5MG
Price$502.95
Updated2021-12-16
Buy

ManufacturerApexBio Technology
Product numberA4548
Product descriptionα-Amanitin
Packaging1mg
Price$243
Updated2021-12-16
Buy

ManufacturerApexBio Technology
Product numberA4548
Product descriptionα-Amanitin
Packaging1mg
Price$538
Updated2026-05-06
Buy

ManufacturerApolloscientific
Product numberBIA8415
Product descriptionalpha-Amanitin, from Amanita Phalloides
Packaging1mg
Price$259
Updated2026-06-04
Buy

ManufacturerApolloscientific
Product numberBIA8415
Product descriptionalpha-Amanitin,fromAmanitaPhalloides
Packaging5mg
Price$540
Updated2021-12-16
Buy

ManufacturerApolloscientific
Product numberBIA8415
Product descriptionalpha-Amanitin, from Amanita Phalloides
Packaging5mg
Price$1218
Updated2026-06-04
Buy

ManufacturerArctom
Product numberHY-19610
Product descriptionα-Amanitin 95.90%
Packaging1mg
Price$569
Updated2026-05-25
Buy

ManufacturerArctom
Product numberHY-19610
Product descriptionα-Amanitin 95.90%
Packaging1mg
Price$569
Updated2026-05-26
Buy

ManufacturerArctom
Product numberHY-19610
Product descriptionα-Amanitin 95.90%
Packaging500μg
Price$361
Updated2026-05-26
Buy

ManufacturerArctom
Product numberHY-19610
Product descriptionα-Amanitin 95.90%
Packaging100μg
Price$177
Updated2026-05-25
Buy

ManufacturerArctom
Product numberHY-19610
Product descriptionα-Amanitin 95.90%
Packaging100μg
Price$177
Updated2026-05-26
Buy

ManufacturerArctom
Product numberHY-19610
Product descriptionα-Amanitin 95.90%
Packaging500μg
Price$361
Updated2026-05-25
Buy

ManufacturerArctom
Product numberHY-19610
Product descriptionα-Amanitin 95.90%
Packaging5mg
Price$1824
Updated2026-05-25
Buy

ManufacturerArctom
Product numberHY-19610
Product descriptionα-Amanitin 95.90%
Packaging5mg
Price$1824
Updated2026-05-26
Buy

Manufacturer	Product number	Product description	Packaging	Price	Updated	Buy
aablocks	AA00BBRV	α-Amanitin ≥90%	1mg	$274	2026-05-28	Buy
AK Scientific	X9108	Alpha-Amanitin	1mg	$336	2021-12-16	Buy
American Custom Chemicals Corporation	PEP0009352	ALPHA-AMANITIN 95.00%	5MG	$502.95	2021-12-16	Buy
ApexBio Technology	A4548	α-Amanitin	1mg	$243	2021-12-16	Buy
ApexBio Technology	A4548	α-Amanitin	1mg	$538	2026-05-06	Buy
Apolloscientific	BIA8415	alpha-Amanitin, from Amanita Phalloides	1mg	$259	2026-06-04	Buy
Apolloscientific	BIA8415	alpha-Amanitin,fromAmanitaPhalloides	5mg	$540	2021-12-16	Buy
Apolloscientific	BIA8415	alpha-Amanitin, from Amanita Phalloides	5mg	$1218	2026-06-04	Buy
Arctom	HY-19610	α-Amanitin 95.90%	1mg	$569	2026-05-25	Buy
Arctom	HY-19610	α-Amanitin 95.90%	1mg	$569	2026-05-26	Buy
Arctom	HY-19610	α-Amanitin 95.90%	500μg	$361	2026-05-26	Buy
Arctom	HY-19610	α-Amanitin 95.90%	100μg	$177	2026-05-25	Buy
Arctom	HY-19610	α-Amanitin 95.90%	100μg	$177	2026-05-26	Buy
Arctom	HY-19610	α-Amanitin 95.90%	500μg	$361	2026-05-25	Buy
Arctom	HY-19610	α-Amanitin 95.90%	5mg	$1824	2026-05-25	Buy
Arctom	HY-19610	α-Amanitin 95.90%	5mg	$1824	2026-05-26	Buy

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Properties

Melting point :254-255 °C(lit.)
alpha :D20 +191°
Boiling point :1622.2±65.0 °C(Predicted)
Density :1.1626 (rough estimate)
refractive index :1.7400 (estimate)
storage temp. :−20°C
solubility :H₂O: 1.0 mg/mL
form :powder
pka :9.63±0.70(Predicted)
color :white to light yellow
biological source :Amanita phalloides
optical activity :+19120 (H2O)
Water Solubility :Soluble to 5 mM in ethanol and to 5 mM in water
ε(extinction coefficient) :13,500 at 310nm in H2O at 1M
Merck :13,370
BRN :1071138
InChIKey :CIORWBWIBBPXCG-PWKRRBCNNA-N
SMILES :CCC(C)C1NC(=O)CNC(=O)C2Cc3c([nH]c4cc(O)ccc34)S(=O)CC(NC(=O)CNC1=O)C(=O)NC(CC(N)=O)C(=O)N5CC(O)CC5C(=O)NC(C(C)C(O)CO)C(=O)N2

Safety Information

Symbol(GHS):

Signal word:

Danger

Hazard statements:

Code	Hazard statements	Hazard class	Category	Signal word	Pictogram	P-Codes
H300	Fatal if swallowed	Acute toxicity,oral	Category 1, 2	Danger		P264, P270, P301+P310, P321, P330,P405, P501
H373	May cause damage to organs through prolonged or repeated exposure	Specific target organ toxicity, repeated exposure	Category 2	Warning		P260, P314, P501

Precautionary statements:

P260	Do not breathe dust/fume/gas/mist/vapours/spray.
P264	Wash hands thoroughly after handling.
P264	Wash skin thouroughly after handling.
P270	Do not eat, drink or smoke when using this product.
P301+P310	IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P314	Get medical advice/attention if you feel unwell.
P405	Store locked up.

Description

α-Amanitin is a cyclic peptide found in several species of the Amanita genus as well as other poisonous fungi. At 1, 10, and 50 μg/ml, respectively, α-amanitin inhibits RNA polymerase II, III, and IV, preventing translocation of the enzymes on DNA, which significantly slows the rate of transcription. RNA polymerase I is insensitive to its effects. This toxin is used in molecular biology to distinguish among types of RNA polymerase in a sample and to arrest RNA synthesis in transcription studies.

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ALPHA-AMANITIN

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