AZ191
|
- $25 - $2100
- Product name: AZ191
- CAS: 1594092-37-1
- MF: C24H27N7O
- MW: 429.52
- EINECS:
- MDL Number:MFCD28015098
- Synonyms:N-[2-methoxy-4-(4-methyl-1-piperazinyl)phenyl]-4-(1-methyl-1h-pyrrolo[2,3-c]pyridin-3-yl)-2-pyrimidinamine, AZ191;[2-Methoxy-4-(4-methyl-piperazin-1-yl)-phenyl]-[4-(1-methyl-1H-pyrrolo[2,3-c]pyridin-3-yl)-pyrimidin-2-yl]-amine;AZ191;AZ-191;AZ 191;CS-1824;N-[2-methoxy-4-(4-methyl-1-piperazinyl)phenyl]-4-(1-methyl-1h-pyrrolo[2,3-c]pyridin-3-yl)-2-pyrimidinamine;2-Pyrimidinamine, N-[2-methoxy-4-(4-methyl-1-piperazinyl)phenyl]-4-(1-methyl-1H-pyrrolo[2,3-c]pyridin-3-yl)-;Inhibitor,AZ-191,Dual specificity tyrosine regulated kinase,AZ191,Dual specificity tyrosine phosphorylation regulated kinase,inhibit,AZ 191,DYRK
24 prices
Selected condition：
Brand
- Adipogen Life Sciences
- AK Scientific
- Ambeed
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- DC Chemicals
- Tocris
- TRC
Package
- 50
- 1mg
- 10
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 250mg
- 1g
- ManufacturerAdipogen Life Sciences
- Product numberAG-CR1-3657-M001
- Product descriptionAZ191 ≥98%
- Packaging1mg
- Price$25
- Updated2021-12-16
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberAG-CR1-3657-M005
- Product descriptionAZ191 ≥98%
- Packaging5mg
- Price$90
- Updated2021-12-16
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberAG-CR1-3657-M025
- Product descriptionAZ191 ≥98%
- Packaging25mg
- Price$360
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberY1892
- Product descriptionAZ191
- Packaging1mg
- Price$133
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberY1892
- Product descriptionAZ191
- Packaging5mg
- Price$218
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA404720
- Product descriptionAz191 98+%
- Packaging10mg
- Price$122
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA404720
- Product descriptionAz191 98+%
- Packaging5mg
- Price$82
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA404720
- Product descriptionAz191 98+%
- Packaging1mg
- Price$37
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number17693
- Product descriptionAZ191 ≥98%
- Packaging1mg
- Price$32
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number17693
- Product descriptionAZ191 ≥98%
- Packaging5mg
- Price$109
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number17693
- Product descriptionAZ191 ≥98%
- Packaging10mg
- Price$199
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number17693
- Product descriptionAZ191 ≥98%
- Packaging25mg
- Price$456
- Updated2024-03-01
- Buy
- ManufacturerChemenu
- Product numberCM295223
- Product descriptionN-(2-Methoxy-4-(4-methylpiperazin-1-yl)phenyl)-4-(1-methyl-1H-pyrrolo[2,3-c]pyridin-3-yl)pyrimidin-2-amine 95%+
- Packaging100mg
- Price$458
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-4277
- Product descriptionAZ191 99.98%
- Packaging5mg
- Price$72
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-4277
- Product descriptionAZ191 99.98%
- Packaging10mg
- Price$108
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-4277
- Product descriptionAZ191 99.98%
- Packaging50mg
- Price$300
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Adipogen Life Sciences | AG-CR1-3657-M001 | AZ191 ≥98% | 1mg | $25 | 2021-12-16 | Buy |
| Adipogen Life Sciences | AG-CR1-3657-M005 | AZ191 ≥98% | 5mg | $90 | 2021-12-16 | Buy |
| Adipogen Life Sciences | AG-CR1-3657-M025 | AZ191 ≥98% | 25mg | $360 | 2021-12-16 | Buy |
| AK Scientific | Y1892 | AZ191 | 1mg | $133 | 2021-12-16 | Buy |
| AK Scientific | Y1892 | AZ191 | 5mg | $218 | 2021-12-16 | Buy |
| Ambeed | A404720 | Az191 98+% | 10mg | $122 | 2021-12-16 | Buy |
| Ambeed | A404720 | Az191 98+% | 5mg | $82 | 2021-12-16 | Buy |
| Ambeed | A404720 | Az191 98+% | 1mg | $37 | 2021-12-16 | Buy |
| Cayman Chemical | 17693 | AZ191 ≥98% | 1mg | $32 | 2024-03-01 | Buy |
| Cayman Chemical | 17693 | AZ191 ≥98% | 5mg | $109 | 2024-03-01 | Buy |
| Cayman Chemical | 17693 | AZ191 ≥98% | 10mg | $199 | 2024-03-01 | Buy |
| Cayman Chemical | 17693 | AZ191 ≥98% | 25mg | $456 | 2024-03-01 | Buy |
| Chemenu | CM295223 | N-(2-Methoxy-4-(4-methylpiperazin-1-yl)phenyl)-4-(1-methyl-1H-pyrrolo[2,3-c]pyridin-3-yl)pyrimidin-2-amine 95%+ | 100mg | $458 | 2021-12-16 | Buy |
| ChemScene | CS-4277 | AZ191 99.98% | 5mg | $72 | 2021-12-16 | Buy |
| ChemScene | CS-4277 | AZ191 99.98% | 10mg | $108 | 2021-12-16 | Buy |
| ChemScene | CS-4277 | AZ191 99.98% | 50mg | $300 | 2021-12-16 | Buy |
Properties
Boiling point :705.3±70.0 °C(Predicted)
Density :1.29±0.1 g/cm3(Predicted)
storage temp. :Keep in dark place,Sealed in dry,Store in freezer, under -20°C
solubility :DMSO: soluble10mg/mL, clear
form :powder
pka :7.76±0.42(Predicted)
color :white to yellow to light brown
Density :1.29±0.1 g/cm3(Predicted)
storage temp. :Keep in dark place,Sealed in dry,Store in freezer, under -20°C
solubility :DMSO: soluble10mg/mL, clear
form :powder
pka :7.76±0.42(Predicted)
color :white to yellow to light brown
Safety Information
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| Signal word: | Danger | |||||||||||||||||||||
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Description
Dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B (DYRK1B) belongs to a family of nuclear-localized protein kinases and participates in the regulation of the cell cycle with key roles in proliferation and differentiation. It is upregulated in solid tumors and gain-of-function mutations in the gene encoding this kinase have been linked to metabolic syndrome. AZ191 is a cell-permeable azaindole that inhibits the serine/threonine kinase activity of DYRK1B (IC50 = 17 nM) with 5-fold and 110-fold selectivity against the related family members DYRK1A and DYRK2, respectively. This compound has been used as a probe to elucidate the mechanism of DYRK1B regulation of cell cycle progression.{28993Related product price
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