BI 6015
|
- $45 - $2406
- Product name: BI 6015
- CAS: 93987-29-2
- MF: C15H13N3O4S
- MW: 331.35
- EINECS:
- MDL Number:MFCD04406654
- Synonyms:BI 6015;2-Methyl-1-(2-methyl-5-nitrophenylsulfonyl)-1H-benzo[d]imidazole;2-Methyl-1-[(2-methyl-5-nitrophenyl)sulfonyl]-1H-benzimidazole;inhibit,promoter,HNF4α,factor,hepatocyte,Inhibitor,diabetes,insulin,BI-6015,BI6015,nuclear,cancer,BI 6015;1H-Benzimidazole, 2-methyl-1-[(2-methyl-5-nitrophenyl)sulfonyl]-;B16015;BI-6015, 10 mM in DMSO;HNF4 Antagonist, BI6015
24 prices
Selected condition：
Brand
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Cayman Chemical
- Matrix Scientific
- Sigma-Aldrich
- Tocris
- TRC
- Usbiological
Package
- 50
- 5mg
- 10
- 10mg
- 25mg
- 50mg
- 100mg
- 250mg
- 25 mg
- ManufacturerAK Scientific
- Product number0937CK
- Product description2-Methyl-1-(2-methyl-5-nitrophenylsulfonyl)-1H-benzo[d]imidazole
- Packaging5mg
- Price$166
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number0937CK
- Product description2-Methyl-1-(2-methyl-5-nitrophenylsulfonyl)-1H-benzo[d]imidazole
- Packaging10mg
- Price$225
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0017250
- Product descriptionBI-6015 95.00%
- Packaging10MG
- Price$256.2
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB5668
- Product descriptionBI 6015
- Packaging5mg
- Price$95
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberB5668
- Product descriptionBI6015
- Packaging10mg
- Price$129
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB5668
- Product descriptionBI 6015
- Packaging10mg
- Price$179
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberB5668
- Product descriptionBI6015
- Packaging5mg
- Price$68
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB5668
- Product descriptionBI6015
- Packaging50mg
- Price$543
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB5668
- Product descriptionBI 6015
- Packaging50mg
- Price$702
- Updated2026-05-06
- Buy
- ManufacturerCayman Chemical
- Product number12032
- Product descriptionBI6015 ≥95%
- Packaging10mg
- Price$86
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number12032
- Product descriptionBI-6015 ≥95%
- Packaging10mg
- Price$95
- Updated2026-04-30
- Buy
- ManufacturerCayman Chemical
- Product number12032
- Product descriptionBI6015 ≥95%
- Packaging5mg
- Price$48
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number12032
- Product descriptionBI-6015 ≥95%
- Packaging5mg
- Price$53
- Updated2026-04-30
- Buy
- ManufacturerCayman Chemical
- Product number12032
- Product descriptionBI-6015 ≥95%
- Packaging25 mg
- Price$192
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number12032
- Product descriptionBI-6015 ≥95%
- Packaging25mg
- Price$212
- Updated2026-04-30
- Buy
- ManufacturerCayman Chemical
- Product number12032
- Product descriptionBI6015 ≥95%
- Packaging50mg
- Price$360
- Updated2024-03-01
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 0937CK | 2-Methyl-1-(2-methyl-5-nitrophenylsulfonyl)-1H-benzo[d]imidazole | 5mg | $166 | 2021-12-16 | Buy |
| AK Scientific | 0937CK | 2-Methyl-1-(2-methyl-5-nitrophenylsulfonyl)-1H-benzo[d]imidazole | 10mg | $225 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0017250 | BI-6015 95.00% | 10MG | $256.2 | 2021-12-16 | Buy |
| ApexBio Technology | B5668 | BI 6015 | 5mg | $95 | 2026-05-06 | Buy |
| ApexBio Technology | B5668 | BI6015 | 10mg | $129 | 2021-12-16 | Buy |
| ApexBio Technology | B5668 | BI 6015 | 10mg | $179 | 2026-05-06 | Buy |
| ApexBio Technology | B5668 | BI6015 | 5mg | $68 | 2021-12-16 | Buy |
| ApexBio Technology | B5668 | BI6015 | 50mg | $543 | 2021-12-16 | Buy |
| ApexBio Technology | B5668 | BI 6015 | 50mg | $702 | 2026-05-06 | Buy |
| Cayman Chemical | 12032 | BI6015 ≥95% | 10mg | $86 | 2024-03-01 | Buy |
| Cayman Chemical | 12032 | BI-6015 ≥95% | 10mg | $95 | 2026-04-30 | Buy |
| Cayman Chemical | 12032 | BI6015 ≥95% | 5mg | $48 | 2024-03-01 | Buy |
| Cayman Chemical | 12032 | BI-6015 ≥95% | 5mg | $53 | 2026-04-30 | Buy |
| Cayman Chemical | 12032 | BI-6015 ≥95% | 25 mg | $192 | 2024-03-01 | Buy |
| Cayman Chemical | 12032 | BI-6015 ≥95% | 25mg | $212 | 2026-04-30 | Buy |
| Cayman Chemical | 12032 | BI6015 ≥95% | 50mg | $360 | 2024-03-01 | Buy |
Properties
Boiling point :570.6±60.0 °C(Predicted)
Density :1.45±0.1 g/cm3(Predicted)
storage temp. :+2C to +8C
solubility :Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 10 mg/ml).
form :Beige powder
pka :0.88±0.10(Predicted)
color :Tan
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 2 months.
InChI :InChI=1S/C15H13N3O4S/c1-10-7-8-12(18(19)20)9-15(10)23(21,22)17-11(2)16-13-5-3-4-6-14(13)17/h3-9H,1-2H3
InChIKey :ILVCPQPMRPHZSG-UHFFFAOYSA-N
SMILES :C1(C)N(S(C2=CC([N+]([O-])=O)=CC=C2C)(=O)=O)C2=CC=CC=C2N=1
Density :1.45±0.1 g/cm3(Predicted)
storage temp. :+2C to +8C
solubility :Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 10 mg/ml).
form :Beige powder
pka :0.88±0.10(Predicted)
color :Tan
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 2 months.
InChI :InChI=1S/C15H13N3O4S/c1-10-7-8-12(18(19)20)9-15(10)23(21,22)17-11(2)16-13-5-3-4-6-14(13)17/h3-9H,1-2H3
InChIKey :ILVCPQPMRPHZSG-UHFFFAOYSA-N
SMILES :C1(C)N(S(C2=CC([N+]([O-])=O)=CC=C2C)(=O)=O)C2=CC=CC=C2N=1
Safety Information
| Symbol(GHS): | ||||||||
|---|---|---|---|---|---|---|---|---|
| Signal word: | ||||||||
| Hazard statements: |
|
|||||||
| Precautionary statements: |
|
Description
Hepatocyte nuclear factor 4α (HNF4α) is a nuclear receptor transcription factor that controls the expression of many genes including those involved in glucose and lipid homeostasis and maintenance of epithelial differentiation. BI6015 is a small molecule antagonist of Hepatocyte nuclear factor 4α (HNF4α) that has been shown to repress the expression of known HNF4α target genes. At concentrations up to 20 μM, BI6015 has been shown to reduce endogenous insulin gene expression by as much as 50-fold in T6PNE cells. The hepatocytes from livers of mice injected with 10 and 30 mg/kg BI6015 exhibit marked, dose-dependent fat accumulation (steatosis). Additionally, at a daily dose of 30 mg/kg, BI6015 induces apoptosis in a human hepatocellular carcinoma mouse model.Related product price
- SU 4312
$32-1200 - AAL-993
$61-1450 - TYRPHOSTIN AG 1296
$11-2709
Suppliers and manufacturers
TargetMol Chemicals Inc.
Career Henan Chemica Co
Wuhan Topule Biopharmaceutical Co., Ltd
Aladdin Scientific
Suzhou Zhixin Biotechnology Co., Ltd.
J & K SCIENTIFIC LTD.
BOC Sciences
Guangzhou Isun Pharmaceutical Co., Ltd
Shanghai TaoSu Biochemical Technology Co., Ltd.
Shanghai Lollane Biological Technology Co.,Ltd.