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ChemicalBook >> CAS DataBase List >> BIS(METHYLTHIO)GLIOTOXIN

BIS(METHYLTHIO)GLIOTOXIN

BIS(METHYLTHIO)GLIOTOXIN price.
  • $86 - $802
  • Product name: BIS(METHYLTHIO)GLIOTOXIN
  • CAS: 74149-38-5
  • MF: C15H20N2O4S2
  • MW: 356.46
  • EINECS:
  • MDL Number:MFCD00133146
  • Synonyms:gliotoxin, bis-dethio-bis(methylthio)-;(3R)-2,3,5aβ,6,10,10a-Hexahydro-6β-hydroxy-3β-(hydroxymethyl)-2-methyl-3α,10aα-bis(methylthio)pyrazino[1,2-a]indole-1,4-dione;2,3,5aβ,6,10,10a-Hexahydro-6β-hydroxy-3β-(hydroxymethyl)-2-methyl-3,10aα-bis(methylthio)pyrazino[1,2-a]indole-1,4-dione;Bis(methylthio)gliotoxin (FR-49175);BIS(METHYLTHIO)GLIOTOXIN;FR-49175;bis-dethio-bis(methylthio)gliotoxin;Pyrazino[1,2-a]indole-1,4-dione, 2,3,5a,6,10,10a-hexahydro-6-hydroxy-3-(hydroxymethyl)-2-methyl-3,10a-bis(methylthio)-, (3R,5aS,6S,10aR)-
Price7 Properties Safety Information Description
7 prices
Selected condition：
Brand
  • AK Scientific
  • Alfa Aesar
  • Cayman Chemical
  • Crysdot
  • TRC
Package
  • 500μg
  • 1mg
  • 2.5mg
  • 5mg
  • ManufacturerAK Scientific
  • Product number2418CB
  • Product descriptionBisdethiobis(methylthio)gliotoxin
  • Packaging1mg
  • Price$276
  • Updated2021-12-16
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ67499
  • Product descriptionBis(methylthio)gliotoxin, 99%
  • Packaging1mg
  • Price$290
  • Updated2023-06-20
  • Buy
  • ManufacturerCayman Chemical
  • Product number26271
  • Product descriptionBis(methylthio)gliotoxin ≥95%
  • Packaging500μg
  • Price$86
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number26271
  • Product descriptionBis(methylthio)gliotoxin ≥95%
  • Packaging1mg
  • Price$161
  • Updated2024-03-01
  • Buy
  • ManufacturerCrysdot
  • Product numberCD32000504
  • Product descriptionBis(methylthio)gliotoxin 95+%
  • Packaging5mg
  • Price$802
  • Updated2021-12-16
  • Buy
  • ManufacturerTRC
  • Product numberB485948
  • Product descriptionBis(methylthio)gliotoxin(FR-49175)
  • Packaging1mg
  • Price$215
  • Updated2021-12-16
  • Buy
  • ManufacturerTRC
  • Product numberB485948
  • Product descriptionBis(methylthio)gliotoxin(FR-49175)
  • Packaging2.5mg
  • Price$525
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 2418CB Bisdethiobis(methylthio)gliotoxin 1mg $276 2021-12-16 Buy
Alfa Aesar J67499 Bis(methylthio)gliotoxin, 99% 1mg $290 2023-06-20 Buy
Cayman Chemical 26271 Bis(methylthio)gliotoxin ≥95% 500μg $86 2024-03-01 Buy
Cayman Chemical 26271 Bis(methylthio)gliotoxin ≥95% 1mg $161 2024-03-01 Buy
Crysdot CD32000504 Bis(methylthio)gliotoxin 95+% 5mg $802 2021-12-16 Buy
TRC B485948 Bis(methylthio)gliotoxin(FR-49175) 1mg $215 2021-12-16 Buy
TRC B485948 Bis(methylthio)gliotoxin(FR-49175) 2.5mg $525 2021-12-16 Buy

Properties

Boiling point :669.6±55.0 °C(Predicted)
Density :1.49±0.1 g/cm3(Predicted)
storage temp. :−20°C
solubility :Chloroform (Slightly), Methanol (Slightly)
form :White solid.
pka :12.69±0.60(Predicted)
color :Off-White to Yellow
biological source :natural
Water Solubility :water: soluble

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P270 Do not eat, drink or smoke when using this product.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P312 Call a POISON CENTER or doctor/physician if you feel unwell.
P330 Rinse mouth.
P363 Wash contaminated clothing before reuse.
P403 Store in a well-ventilated place.

Description

Bis(methylthio)gliotoxin (FR-49175) is a toxic metabolite with anthiphagocytic and immunosuppressive properties synthesized by pathogenic fungi such as Aspergillus fumigatus. Bis(methylthio)gliotoxin (FR-49175) is an analog of gliotoxin known to inhibit PAF-induced platelet aggregation and collagen-aggregation, but has no activity with arachidonic or ADP induced aggregation. Shown to speed up PAF hydrolysis and inhibit PAF-mediated caspase 3 activation. From guinea-pig experiments, reported to Inhibit PAF-induced bronchoconstriction.

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Suppliers and manufacturers

TargetMol Chemicals Inc.
Aladdin Scientific
DAYANG CHEM (HANGZHOU) CO.,LTD BioBioPha Co., Ltd. ALB Technology Limited Shanghai YuanYe Biotechnology Co., Ltd. Shanghai Hongye Biotechnology Co. Ltd ChemeGen(Shanghai) Biotechnology Co.,Ltd. Shanghai Binsui Biotechnology Co., Ltd. Shanghai Bohu Biotechnology Co., LTD