(+/-)-BLEBBISTATIN
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- $70 - $1960
- Product name: (+/-)-BLEBBISTATIN
- CAS: 674289-55-5
- MF: C18H16N2O2
- MW: 292.33
- EINECS:
- MDL Number:MFCD04113775
- Synonyms:(R)-(+)-BLEBBISTATIN;(3AS)-(-)-1,2,3,3A-TETRAHYDRO-3A-HYDROXY-6-METHYL-1-PHENYL-4H-PYRROLO[2,3-B]QUINOLIN-4-ONE;(+/-)-1-PHENYL-1,2,3,4-TETRAHYDRO-4-HYDROXYPYRROLO[2,3-B]-7-METHYLQUINOLIN-4-ONE;(+/-)-1,2,3,3A-TETRAHYDRO-3A-HYDROXY-6-METHYL-1-PHENYL-4H-PYRROLO[2,3-B]QUINOLIN-4-ONE;(+/-)-1-Phenyl-1,2,3,4-tetrahydro-4-hydroxypyrrolo[2,3-β]-7-methylquinolin-4-one;1,2,3,3a-Tetrahydro-3a-hydroxy-6-methyl-1-phenyl-4H-pyrrolo[2,3-β]quinolin-4-one;(3aS)-1,2,3,3a-Tetrahydro-3a-hydroxy-6-methyl-1-phenyl-4H-pyrrolo[2,3-β]quinolin-4-one;(3aR)-1,2,3,3a-Tetrahydro-3a-hydroxy-6-methyl-1-phenyl-4H-pyrrolo[2,3-β]quinolin-4-one
21 prices
Selected condition：
Brand
- American Custom Chemicals Corporation
- ApexBio Technology
- Axon Medchem
- Biosynth Carbosynth
- Cayman Chemical
- ChemScene
- Crysdot
- Medical Isotopes, Inc.
- Sigma-Aldrich
- Tocris
- TRC
Package
- 5MG
- 1
- 1mg
- 10MG
- 20mg
- 25mg
- 50mg
- 100MG
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0001058
- Product description(+/-)-BLEBBISTATIN 95.00%
- Packaging5MG
- Price$550
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0001058
- Product description(+/-)-BLEBBISTATIN 95.00%
- Packaging10MG
- Price$620
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0001058
- Product description(+/-)-BLEBBISTATIN 95.00%
- Packaging100MG
- Price$1960
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB6847
- Product description(±)-Blebbistatin
- Packaging1mg
- Price$402
- Updated2021-12-16
- Buy
- ManufacturerAxon Medchem
- Product numberAxon2718
- Product description(±)-Blebbistatin 99%
- Packaging5mg
- Price$104.5
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFB18838
- Product description(+/-)-Blebbistatin
- Packaging50mg
- Price$437.5
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFB18838
- Product description(+/-)-Blebbistatin
- Packaging10mg
- Price$450
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFB18838
- Product description(+/-)-Blebbistatin
- Packaging20mg
- Price$800
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number13186
- Product description(±)-Blebbistatin ≥98%
- Packaging5mg
- Price$86
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number13186
- Product description(±)-Blebbistatin ≥98%
- Packaging10mg
- Price$189
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number13186
- Product description(±)-Blebbistatin ≥98%
- Packaging25mg
- Price$336
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number13186
- Product description(±)-Blebbistatin ≥98%
- Packaging50mg
- Price$629
- Updated2024-03-01
- Buy
- ManufacturerChemScene
- Product numberCS-0007920
- Product descriptionBlebbistatin 99.64%
- Packaging1mg
- Price$255
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD11074782
- Product description(±)bebbistatin 97%
- Packaging50mg
- Price$430
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD11074782
- Product description(±)bebbistatin 97%
- Packaging100mg
- Price$825
- Updated2021-12-16
- Buy
- ManufacturerMedical Isotopes, Inc.
- Product number7537
- Product description(+/-)-Blebbistatin
- Packaging50mg
- Price$1880
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| American Custom Chemicals Corporation | INB0001058 | (+/-)-BLEBBISTATIN 95.00% | 5MG | $550 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | INB0001058 | (+/-)-BLEBBISTATIN 95.00% | 10MG | $620 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | INB0001058 | (+/-)-BLEBBISTATIN 95.00% | 100MG | $1960 | 2021-12-16 | Buy |
| ApexBio Technology | B6847 | (±)-Blebbistatin | 1mg | $402 | 2021-12-16 | Buy |
| Axon Medchem | Axon2718 | (±)-Blebbistatin 99% | 5mg | $104.5 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FB18838 | (+/-)-Blebbistatin | 50mg | $437.5 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FB18838 | (+/-)-Blebbistatin | 10mg | $450 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FB18838 | (+/-)-Blebbistatin | 20mg | $800 | 2021-12-16 | Buy |
| Cayman Chemical | 13186 | (±)-Blebbistatin ≥98% | 5mg | $86 | 2024-03-01 | Buy |
| Cayman Chemical | 13186 | (±)-Blebbistatin ≥98% | 10mg | $189 | 2024-03-01 | Buy |
| Cayman Chemical | 13186 | (±)-Blebbistatin ≥98% | 25mg | $336 | 2024-03-01 | Buy |
| Cayman Chemical | 13186 | (±)-Blebbistatin ≥98% | 50mg | $629 | 2024-03-01 | Buy |
| ChemScene | CS-0007920 | Blebbistatin 99.64% | 1mg | $255 | 2021-12-16 | Buy |
| Crysdot | CD11074782 | (±)bebbistatin 97% | 50mg | $430 | 2021-12-16 | Buy |
| Crysdot | CD11074782 | (±)bebbistatin 97% | 100mg | $825 | 2021-12-16 | Buy |
| Medical Isotopes, Inc. | 7537 | (+/-)-Blebbistatin | 50mg | $1880 | 2021-12-16 | Buy |
Properties
Melting point :210-212°C
Boiling point :507.3±60.0 °C(Predicted)
Density :1.31±0.1 g/cm3(Predicted)
storage temp. :−20°C
solubility :Chloroform (Slightly), Dichloromethane, DMSO, Ethyl Acetate, Methanol
pka :11.15±0.20(Predicted)
form :Bright yellow solid.
color :Yellow
InChI :InChI=1S/C18H16N2O2/c1-12-7-8-15-14(11-12)16(21)18(22)9-10-20(17(18)19-15)13-5-3-2-4-6-13/h2-8,11,22H,9-10H2,1H3
InChIKey :LZAXPYOBKSJSEX-UHFFFAOYSA-N
SMILES :N1C2=C(C=C(C)C=C2)C(=O)C2(O)CCN(C3=CC=CC=C3)C=12
CAS DataBase Reference :674289-55-5
Boiling point :507.3±60.0 °C(Predicted)
Density :1.31±0.1 g/cm3(Predicted)
storage temp. :−20°C
solubility :Chloroform (Slightly), Dichloromethane, DMSO, Ethyl Acetate, Methanol
pka :11.15±0.20(Predicted)
form :Bright yellow solid.
color :Yellow
InChI :InChI=1S/C18H16N2O2/c1-12-7-8-15-14(11-12)16(21)18(22)9-10-20(17(18)19-15)13-5-3-2-4-6-13/h2-8,11,22H,9-10H2,1H3
InChIKey :LZAXPYOBKSJSEX-UHFFFAOYSA-N
SMILES :N1C2=C(C=C(C)C=C2)C(=O)C2(O)CCN(C3=CC=CC=C3)C=12
CAS DataBase Reference :674289-55-5
Safety Information
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| Signal word: | Warning | |||||||||||||||||||||||||||||||||||
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Description
(±)-Blebbistatin is a selective cell-permeable inhibitor of non-muscle myosin II ATPases. It rapidly and reversibly inhibits Mg-ATPase activity and in vitro motility of non-muscle myosin IIA and IIB for several species (IC50 = 0.5-5.0 μM), while poorly inhibiting smooth muscle myosin (IC50 = 80 μM). Through these effects, blebbistatin blocks apoptosis-related bleb formation, directed cell migration and cytokinesis in vertebrate cells. Blebbistatin is inactivated by UV light, which may be particularly important in fluorescent cell imaging applications. Purified enantiomers of Blebbistatin are also available from Cayman ((?)-Blebbistatin - ).More related product prices
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