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ChemicalBook >> CAS DataBase List >> BUDIPINE

BUDIPINE

BUDIPINE price.
  • $36 - $1750.98
  • Product name: BUDIPINE
  • CAS: 57982-78-2
  • MF: C21H27N
  • MW: 293.45
  • EINECS:261-062-4
  • MDL Number:MFCD00866585
  • Synonyms:BUDIPINE;1-(1,1-dimethylethyl)-4,4-diphenyl-piperidin ;1-(1,1-dimethylethyl)-4,4-diphenylpiperidine ;budipin ;1-TERT-BUTYL-4,4-DIPHENYL-PIPERIDINE;BUDIPINE(FORR&DONLY);4,4-diphenyl-1-tert-butyl-piperidine;Piperidine,1-(1,1-dimethylethyl)-4,4-diphenyl-
20 prices
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Brand
  • AK Scientific
  • American Custom Chemicals Corporation
  • Arctom
  • Biosynth Carbosynth
  • Chemenu
  • Crysdot
  • CSNpharm
  • TRC
Package
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 1G
  • 5G
  • ManufacturerAK Scientific
  • Product numberM128
  • Product descriptionBudipine
  • Packaging5mg
  • Price$108
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0007854
  • Product descriptionBUDIPINE 95.00%
  • Packaging1G
  • Price$1379.7
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0007854
  • Product descriptionBUDIPINE 95.00%
  • Packaging5G
  • Price$1750.98
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS008066
  • Product description1-(tert-Butyl)-4,4-diphenylpiperidine 95%
  • Packaging5mg
  • Price$36
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS008066
  • Product description1-(tert-Butyl)-4,4-diphenylpiperidine 95%
  • Packaging25mg
  • Price$72
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS008066
  • Product description1-(tert-Butyl)-4,4-diphenylpiperidine 95%
  • Packaging100mg
  • Price$141
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS008066
  • Product description1-(tert-Butyl)-4,4-diphenylpiperidine 95%
  • Packaging250mg
  • Price$245
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS008066
  • Product description1-(tert-Butyl)-4,4-diphenylpiperidine 95%
  • Packaging1g
  • Price$642
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFB156517
  • Product description1-tert-butyl-4,4-Diphenyl-piperidine
  • Packaging5mg
  • Price$50
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFB156517
  • Product description1-tert-butyl-4,4-Diphenyl-piperidine
  • Packaging10mg
  • Price$80
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFB156517
  • Product description1-tert-butyl-4,4-Diphenyl-piperidine
  • Packaging25mg
  • Price$150
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFB156517
  • Product description1-tert-butyl-4,4-Diphenyl-piperidine
  • Packaging50mg
  • Price$225
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFB156517
  • Product description1-tert-butyl-4,4-Diphenyl-piperidine
  • Packaging100mg
  • Price$300
  • Updated2021-12-16
  • Buy
  • ManufacturerChemenu
  • Product numberCM180469
  • Product description1-(tert-butyl)-4,4-diphenylpiperidine 95%
  • Packaging1g
  • Price$580
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD33000216
  • Product descriptionBudipine 95%
  • Packaging250mg
  • Price$245
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD33000216
  • Product descriptionBudipine 95%
  • Packaging1g
  • Price$613
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific M128 Budipine 5mg $108 2021-12-16 Buy
American Custom Chemicals Corporation API0007854 BUDIPINE 95.00% 1G $1379.7 2021-12-16 Buy
American Custom Chemicals Corporation API0007854 BUDIPINE 95.00% 5G $1750.98 2021-12-16 Buy
Arctom AS008066 1-(tert-Butyl)-4,4-diphenylpiperidine 95% 5mg $36 2021-12-16 Buy
Arctom AS008066 1-(tert-Butyl)-4,4-diphenylpiperidine 95% 25mg $72 2021-12-16 Buy
Arctom AS008066 1-(tert-Butyl)-4,4-diphenylpiperidine 95% 100mg $141 2021-12-16 Buy
Arctom AS008066 1-(tert-Butyl)-4,4-diphenylpiperidine 95% 250mg $245 2021-12-16 Buy
Arctom AS008066 1-(tert-Butyl)-4,4-diphenylpiperidine 95% 1g $642 2021-12-16 Buy
Biosynth Carbosynth FB156517 1-tert-butyl-4,4-Diphenyl-piperidine 5mg $50 2021-12-16 Buy
Biosynth Carbosynth FB156517 1-tert-butyl-4,4-Diphenyl-piperidine 10mg $80 2021-12-16 Buy
Biosynth Carbosynth FB156517 1-tert-butyl-4,4-Diphenyl-piperidine 25mg $150 2021-12-16 Buy
Biosynth Carbosynth FB156517 1-tert-butyl-4,4-Diphenyl-piperidine 50mg $225 2021-12-16 Buy
Biosynth Carbosynth FB156517 1-tert-butyl-4,4-Diphenyl-piperidine 100mg $300 2021-12-16 Buy
Chemenu CM180469 1-(tert-butyl)-4,4-diphenylpiperidine 95% 1g $580 2021-12-16 Buy
Crysdot CD33000216 Budipine 95% 250mg $245 2021-12-16 Buy
Crysdot CD33000216 Budipine 95% 1g $613 2021-12-16 Buy

Properties

Melting point :108.5°C
Boiling point :425.29°C (rough estimate)
Density :0.9665 (rough estimate)
refractive index :1.4900 (estimate)
storage temp. :2-8°C
solubility :DMSO : 25 mg/mL (85.19 mM; Need ultrasonic)
form :Solid
pka :10.36±0.10(Predicted)
color :Light yellow to khaki

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H332 Harmful if inhaled Acute toxicity,inhalation Category 4 Warning GHS hazard pictograms P261, P271, P304+P340, P312
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P310 Immediately call a POISON CENTER or doctor/physician.

Description

Parkinsan was launched in Germany as a centrally-active anti-Parkinsonian agent. It can be prepared in three steps: a Mannich-aldol sequence to assemble the 4-phenylpiperidine scaffold followed by a Friedel-Crafts reaction to introduce the second phenyl ring. Parkinsan is effective for the treatment of Parkinsonian tremors and is similar in action to, but more potent than, biperiden. It exhibits use-dependent, open channel, uncompetitive NMDA receptor antagonistic activity. This may occur by binding to the PCP site in addition to interacting with sigma, binding sites in the frontal cortex. Parkinsan is also an antagonist at presynaptic muscarinic autoreceptors but facilitation of direct or indirect dopaminergic transmission does not contribute to its actions. While its mechanism of action is not completely understood, it has a weak inhibitory effect on dopamine reuptake, inhibits evoked GABA release (with low affinity for GABA-A receptors and a lower affinity for benzodiazepine receptors), and has a weak inhibitory effect on MAO-B.

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