Welcome to chemicalbook!
400-158-6606
Inquriy
Try our best to find the right business for you.
Do not miss inquiry messages Please log in to view all inquiry messages.

Welcome back!

ChemicalBook >> CAS DataBase List >> Baricitinib

Baricitinib

Baricitinib price.
  • $37 - $1802
  • Product name: Baricitinib
  • CAS: 1187594-09-7
  • MF: C16H17N7O2S
  • MW: 371.42
  • EINECS:691-421-4
  • MDL Number:MFCD21608464
  • Synonyms:1-(Ethylsulfonyl)-3-[4-(7H-pyrrolo[2,3-d]pyriMidin-4-yl)-1H-pyrazol-1-yl]-3-azetidineacetonitrile;Baricitinib;INCB 028050;LY 3009104;BARICITINIB;INCB28050;LY3009104;Baricitinib (LY3009104);2-(3-(4-(3H-Pyrrolo[2,3-d]pyriMidin-4-yl)-1H-pyrazol-1-yl)-1-(ethylsulfonyl)azetidin-3-yl)acetonitrile;Baricitinib/INCB 028050/LY3009104
46 prices
Selected condition:
Brand
  • Adipogen Life Sciences
  • AK Scientific
  • ApexBio Technology
  • Apolloscientific
  • Arctom
  • AvaChem
  • Axon Medchem
  • Biorbyt Ltd
  • Biosynth Carbosynth
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Tocris
  • TRC
Package
  • 1mg
  • 5mg
  • 10mg
  • 20mg
  • 25mg
  • 50mg
  • 200mg
  • 50
  • 100mg
  • 10mM(in 1mL DMSO)
  • 250mg
  • 500mg
  • 1g
  • 10g
  • ManufacturerAdipogen Life Sciences
  • Product numberAG-CR1-3734-M250
  • Product descriptionBaricitinib ≥98%(HPLC)
  • Packaging250mg
  • Price$120
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberY0439
  • Product descriptionBaricitinib
  • Packaging250mg
  • Price$218
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberY0439
  • Product descriptionBaricitinib
  • Packaging500mg
  • Price$320
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4141
  • Product descriptionBaricitinib(LY3009104,INCB028050)
  • Packaging5mg
  • Price$120
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4141
  • Product descriptionBaricitinib(LY3009104,INCB028050)
  • Packaging10mM(in 1mL DMSO)
  • Price$130
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4141
  • Product descriptionBaricitinib(LY3009104,INCB028050)
  • Packaging10mg
  • Price$160
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4141
  • Product descriptionBaricitinib(LY3009104,INCB028050)
  • Packaging50mg
  • Price$520
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4141
  • Product descriptionBaricitinib(LY3009104,INCB028050)
  • Packaging200mg
  • Price$1360
  • Updated2021-12-16
  • Buy
  • ManufacturerApolloscientific
  • Product numberBISN0315
  • Product descriptionBaricitinib
  • Packaging5mg
  • Price$68
  • Updated2021-12-16
  • Buy
  • ManufacturerApolloscientific
  • Product numberBISN0315
  • Product descriptionBaricitinib
  • Packaging10mg
  • Price$108
  • Updated2021-12-16
  • Buy
  • ManufacturerApolloscientific
  • Product numberBISN0315
  • Product descriptionBaricitinib
  • Packaging50mg
  • Price$264
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberCFN60434
  • Product descriptionBaricitinib(INCB028050)
  • Packaging20mg
  • Price$218
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number3630
  • Product descriptionBaricitinib
  • Packaging10mg
  • Price$39
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number3630
  • Product descriptionBaricitinib
  • Packaging100mg
  • Price$79
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number3630
  • Product descriptionBaricitinib
  • Packaging1g
  • Price$229
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number3630
  • Product descriptionBaricitinib
  • Packaging10g
  • Price$1290
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Adipogen Life Sciences AG-CR1-3734-M250 Baricitinib ≥98%(HPLC) 250mg $120 2021-12-16 Buy
AK Scientific Y0439 Baricitinib 250mg $218 2021-12-16 Buy
AK Scientific Y0439 Baricitinib 500mg $320 2021-12-16 Buy
ApexBio Technology A4141 Baricitinib(LY3009104,INCB028050) 5mg $120 2021-12-16 Buy
ApexBio Technology A4141 Baricitinib(LY3009104,INCB028050) 10mM(in 1mL DMSO) $130 2021-12-16 Buy
ApexBio Technology A4141 Baricitinib(LY3009104,INCB028050) 10mg $160 2021-12-16 Buy
ApexBio Technology A4141 Baricitinib(LY3009104,INCB028050) 50mg $520 2021-12-16 Buy
ApexBio Technology A4141 Baricitinib(LY3009104,INCB028050) 200mg $1360 2021-12-16 Buy
Apolloscientific BISN0315 Baricitinib 5mg $68 2021-12-16 Buy
Apolloscientific BISN0315 Baricitinib 10mg $108 2021-12-16 Buy
Apolloscientific BISN0315 Baricitinib 50mg $264 2021-12-16 Buy
Arctom CFN60434 Baricitinib(INCB028050) 20mg $218 2021-12-16 Buy
AvaChem 3630 Baricitinib 10mg $39 2021-12-16 Buy
AvaChem 3630 Baricitinib 100mg $79 2021-12-16 Buy
AvaChem 3630 Baricitinib 1g $229 2021-12-16 Buy
AvaChem 3630 Baricitinib 10g $1290 2021-12-16 Buy

Properties

Melting point :212-215°C
Density :1.56
storage temp. :-20°C
solubility :Soluble in DMSO (up to 30 mg/ml) or in DMF (up to 50 mg/ml).
pka :11.66±0.50(Predicted)
form :solid
color :White or off-white
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or DMF may be stored at -20°C for up to 3 months.
InChI :InChI=1S/C16H17N7O2S/c1-2-26(24,25)22-9-16(10-22,4-5-17)23-8-12(7-21-23)14-13-3-6-18-15(13)20-11-19-14/h3,6-8,11H,2,4,9-10H2,1H3,(H,18,19,20)
InChIKey :XUZMWHLSFXCVMG-UHFFFAOYSA-N
SMILES :N1(S(CC)(=O)=O)CC(N2C=C(C3N=CN=C4NC=CC4=3)C=N2)(CC#N)C1

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
Precautionary statements:
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Janus kinases (JAKs) are non-receptor kinases that mediate signaling through cytokine receptors, often to members of the signal transducer and activator of transcription (Stat) family. Baricitinib is an orally bioavailable, reversible inhibitor of JAK1 and JAK2 (IC50s = 5.9 and 5.7 nM, respectively) that has been shown to inhibit cytokine-induced phosphorylation of STAT3 in healthy human volunteers. It has potential application in various inflammatory disorders, including rheumatoid arthritis.