Betulinic acid
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- $5 - $904.94
- Product name: Betulinic acid
- CAS: 472-15-1
- MF: C30H48O3
- MW: 456.71
- EINECS:207-448-8
- MDL Number:MFCD00009619
- Synonyms:3BETA-HYDROXY-20(29)-LUPENE-28-OIC ACID;3BETA-HYDROXY-20(29)-LUPAENE-28-OIC ACID;3B-HYDROXY-20(29)-LUPENE-28-OIC ACID;Birch bark extract/β-Amyrin/betulinic acid;3-B-HYDROXY-LUPA-20(30)-ENE 28-OIC ACID;BETULINIC ACID;LUP-20(29)-EN-28-OIC ACID, 3-HYDROXY-, (3B)-;Lup-20(29)-en-28-oic acid, 3-hydroxy-, (3beta)-
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Brand
- Adipogen Life Sciences
- AHH
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- AvaChem
- Biorbyt Ltd
- Biosynth Carbosynth
- BroadPharm
- Cayman Chemical
- Chem-Impex
- ChemScene
- Crysdot
- DC Chemicals
- Iris Biotech GmbH
- JR MediChem
- Matrix Scientific
- Medical Isotopes, Inc.
- Sigma-Aldrich
- TCI Chemical
- Tocris
- Usbiological
Package
- 10mg
- 2,5g
- 5MG
- 20mg
- 25mg
- 50mg
- 100mg
- 10
- 250mg
- 500mg
- 1g
- 2g
- 5g
- 10g
- 25g
- 10mM(in 1mL DMSO)
- ManufacturerAdipogen Life Sciences
- Product numberAG-CN2-0417-M500
- Product descriptionBetulinicacid(>97%) ≥97%(HPLC)
- Packaging500mg
- Price$185
- Updated2021-12-16
- Buy
- ManufacturerAHH
- Product numberMT-47879
- Product descriptionBetulinic acid 98%
- Packaging1g
- Price$830
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number2267AH
- Product descriptionBetulinic acid
- Packaging5g
- Price$321
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA200416
- Product description(1R,3aS,5aR,5bR,7aR,9S,11aR,11bR,13aR,13bR)-9-Hydroxy-5a,5b,8,8,11a-pentamethyl-1-(prop-1-en-2-yl)icosahydro-1H-cyclopenta[a]chrysene-3a-carboxylicacid 98+%
- Packaging25mg
- Price$5
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA200416
- Product description(1R,3aS,5aR,5bR,7aR,9S,11aR,11bR,13aR,13bR)-9-Hydroxy-5a,5b,8,8,11a-pentamethyl-1-(prop-1-en-2-yl)icosahydro-1H-cyclopenta[a]chrysene-3a-carboxylicacid 98+%
- Packaging50mg
- Price$7
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA200416
- Product description(1R,3aS,5aR,5bR,7aR,9S,11aR,11bR,13aR,13bR)-9-Hydroxy-5a,5b,8,8,11a-pentamethyl-1-(prop-1-en-2-yl)icosahydro-1H-cyclopenta[a]chrysene-3a-carboxylicacid 98+%
- Packaging100mg
- Price$9
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA200416
- Product description(1R,3aS,5aR,5bR,7aR,9S,11aR,11bR,13aR,13bR)-9-Hydroxy-5a,5b,8,8,11a-pentamethyl-1-(prop-1-en-2-yl)icosahydro-1H-cyclopenta[a]chrysene-3a-carboxylicacid 98+%
- Packaging250mg
- Price$11
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA200416
- Product description(1R,3aS,5aR,5bR,7aR,9S,11aR,11bR,13aR,13bR)-9-Hydroxy-5a,5b,8,8,11a-pentamethyl-1-(prop-1-en-2-yl)icosahydro-1H-cyclopenta[a]chrysene-3a-carboxylicacid 98+%
- Packaging1g
- Price$11
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA200416
- Product description(1R,3aS,5aR,5bR,7aR,9S,11aR,11bR,13aR,13bR)-9-Hydroxy-5a,5b,8,8,11a-pentamethyl-1-(prop-1-en-2-yl)icosahydro-1H-cyclopenta[a]chrysene-3a-carboxylicacid 98+%
- Packaging5g
- Price$90
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA200416
- Product description(1R,3aS,5aR,5bR,7aR,9S,11aR,11bR,13aR,13bR)-9-Hydroxy-5a,5b,8,8,11a-pentamethyl-1-(prop-1-en-2-yl)icosahydro-1H-cyclopenta[a]chrysene-3a-carboxylicacid 98+%
- Packaging10g
- Price$90
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA200416
- Product description(1R,3aS,5aR,5bR,7aR,9S,11aR,11bR,13aR,13bR)-9-Hydroxy-5a,5b,8,8,11a-pentamethyl-1-(prop-1-en-2-yl)icosahydro-1H-cyclopenta[a]chrysene-3a-carboxylicacid 98+%
- Packaging25g
- Price$170
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0045790
- Product descriptionBETULINIC ACID 95.00%
- Packaging5MG
- Price$510
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0045790
- Product descriptionBETULINIC ACID 95.00%
- Packaging1G
- Price$904.94
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA3237
- Product descriptionBetulinic acid
- Packaging10mM(in 1mL DMSO)
- Price$50
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS019600
- Product description(1R,3aS,5aR,5bR,7aR,9S,11aR,11bR,13aR,13bR)-9-Hydroxy-5a,5b,8,8,11a-pentamethyl-1-(prop-1-en-2-yl)icosahydro-1H-cyclopenta[a]chrysene-3a-carboxylicacid ≥98%
- Packaging25mg
- Price$5
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS019600
- Product description(1R,3aS,5aR,5bR,7aR,9S,11aR,11bR,13aR,13bR)-9-Hydroxy-5a,5b,8,8,11a-pentamethyl-1-(prop-1-en-2-yl)icosahydro-1H-cyclopenta[a]chrysene-3a-carboxylicacid ≥98%
- Packaging50mg
- Price$7
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Adipogen Life Sciences | AG-CN2-0417-M500 | Betulinicacid(>97%) ≥97%(HPLC) | 500mg | $185 | 2021-12-16 | Buy |
| AHH | MT-47879 | Betulinic acid 98% | 1g | $830 | 2021-12-16 | Buy |
| AK Scientific | 2267AH | Betulinic acid | 5g | $321 | 2021-12-16 | Buy |
| Ambeed | A200416 | (1R,3aS,5aR,5bR,7aR,9S,11aR,11bR,13aR,13bR)-9-Hydroxy-5a,5b,8,8,11a-pentamethyl-1-(prop-1-en-2-yl)icosahydro-1H-cyclopenta[a]chrysene-3a-carboxylicacid 98+% | 25mg | $5 | 2021-12-16 | Buy |
| Ambeed | A200416 | (1R,3aS,5aR,5bR,7aR,9S,11aR,11bR,13aR,13bR)-9-Hydroxy-5a,5b,8,8,11a-pentamethyl-1-(prop-1-en-2-yl)icosahydro-1H-cyclopenta[a]chrysene-3a-carboxylicacid 98+% | 50mg | $7 | 2021-12-16 | Buy |
| Ambeed | A200416 | (1R,3aS,5aR,5bR,7aR,9S,11aR,11bR,13aR,13bR)-9-Hydroxy-5a,5b,8,8,11a-pentamethyl-1-(prop-1-en-2-yl)icosahydro-1H-cyclopenta[a]chrysene-3a-carboxylicacid 98+% | 100mg | $9 | 2021-12-16 | Buy |
| Ambeed | A200416 | (1R,3aS,5aR,5bR,7aR,9S,11aR,11bR,13aR,13bR)-9-Hydroxy-5a,5b,8,8,11a-pentamethyl-1-(prop-1-en-2-yl)icosahydro-1H-cyclopenta[a]chrysene-3a-carboxylicacid 98+% | 250mg | $11 | 2021-12-16 | Buy |
| Ambeed | A200416 | (1R,3aS,5aR,5bR,7aR,9S,11aR,11bR,13aR,13bR)-9-Hydroxy-5a,5b,8,8,11a-pentamethyl-1-(prop-1-en-2-yl)icosahydro-1H-cyclopenta[a]chrysene-3a-carboxylicacid 98+% | 1g | $11 | 2021-12-16 | Buy |
| Ambeed | A200416 | (1R,3aS,5aR,5bR,7aR,9S,11aR,11bR,13aR,13bR)-9-Hydroxy-5a,5b,8,8,11a-pentamethyl-1-(prop-1-en-2-yl)icosahydro-1H-cyclopenta[a]chrysene-3a-carboxylicacid 98+% | 5g | $90 | 2021-12-16 | Buy |
| Ambeed | A200416 | (1R,3aS,5aR,5bR,7aR,9S,11aR,11bR,13aR,13bR)-9-Hydroxy-5a,5b,8,8,11a-pentamethyl-1-(prop-1-en-2-yl)icosahydro-1H-cyclopenta[a]chrysene-3a-carboxylicacid 98+% | 10g | $90 | 2021-12-16 | Buy |
| Ambeed | A200416 | (1R,3aS,5aR,5bR,7aR,9S,11aR,11bR,13aR,13bR)-9-Hydroxy-5a,5b,8,8,11a-pentamethyl-1-(prop-1-en-2-yl)icosahydro-1H-cyclopenta[a]chrysene-3a-carboxylicacid 98+% | 25g | $170 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0045790 | BETULINIC ACID 95.00% | 5MG | $510 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0045790 | BETULINIC ACID 95.00% | 1G | $904.94 | 2021-12-16 | Buy |
| ApexBio Technology | A3237 | Betulinic acid | 10mM(in 1mL DMSO) | $50 | 2021-12-16 | Buy |
| Arctom | AS019600 | (1R,3aS,5aR,5bR,7aR,9S,11aR,11bR,13aR,13bR)-9-Hydroxy-5a,5b,8,8,11a-pentamethyl-1-(prop-1-en-2-yl)icosahydro-1H-cyclopenta[a]chrysene-3a-carboxylicacid ≥98% | 25mg | $5 | 2021-12-16 | Buy |
| Arctom | AS019600 | (1R,3aS,5aR,5bR,7aR,9S,11aR,11bR,13aR,13bR)-9-Hydroxy-5a,5b,8,8,11a-pentamethyl-1-(prop-1-en-2-yl)icosahydro-1H-cyclopenta[a]chrysene-3a-carboxylicacid ≥98% | 50mg | $7 | 2021-12-16 | Buy |
Properties
Melting point :295-298 °C (dec.) (lit.)
Boiling point :550.0±33.0 °C(Predicted)
alpha :D25 +7.5° (c = 0.37 in pyridine)
Density :1.065±0.06 g/cm3(Predicted)
refractive index :7.8 ° (C=0.9, Pyridine)
storage temp. :2-8°C
solubility :Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 25 mg/ml).
pka :4.61±0.70(Predicted)
color :White or off-white
optical activity :[α]20/D +7.8°, c = 0.9 in pyridine
Merck :14,1190
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 2 months.
InChIKey :QGJZLNKBHJESQX-FZFNOLFKSA-N
LogP :7.653 (est)
CAS DataBase Reference :472-15-1(CAS DataBase Reference)
Boiling point :550.0±33.0 °C(Predicted)
alpha :D25 +7.5° (c = 0.37 in pyridine)
Density :1.065±0.06 g/cm3(Predicted)
refractive index :7.8 ° (C=0.9, Pyridine)
storage temp. :2-8°C
solubility :Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 25 mg/ml).
pka :4.61±0.70(Predicted)
color :White or off-white
optical activity :[α]20/D +7.8°, c = 0.9 in pyridine
Merck :14,1190
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 2 months.
InChIKey :QGJZLNKBHJESQX-FZFNOLFKSA-N
LogP :7.653 (est)
CAS DataBase Reference :472-15-1(CAS DataBase Reference)
Safety Information
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| Signal word: | Warning | ||||||||||||||
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Description
Betulinic acid is a natural plant triterpenoid that is structurally related to mammalian bile acids. It is an agonist of the G protein-coupled bile acid receptor TGR5 (EC50 = 1 μM), which might be linked with its ability to alter gene expression and fatty liver development in cells and mice given ethanol. Betulinic acid also reduces NF-κB signaling and expression of microRNA-33 in LPS-treated macrophages, increasing levels of the ATP-binding cassette (ABC) cholesterol transporter ABCA1. It also inhibits replication of HIV-1 (IC50 = 1.4 μM) and has cytotoxic effects against cancer cells.Related product price
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Suppliers and manufacturers
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