Binimetinib
|
- $50.2 - $9990
- Product name: Binimetinib
- CAS: 606143-89-9
- MF: C17H15BrF2N4O3
- MW: 441.23
- EINECS:
- MDL Number:MFCD22124525
- Synonyms:5-[(4-Bromo-2-fluorophenyl)amino]-4-fluoro-N-(2-hydroxyethoxy)-1-methyl-1H-benzimidazole-6-carboxamide;MEK162 (ARRY-438162);MEK162 (ARRY-162, ARRY-438162);BiniMetinib (MEK162, ARRY-162, ARRY-438162);1H-Benzimidazole-6-carboxamide, 5-[(4-bromo-2-fluorophenyl)amino]-4-fluoro-N-(2-hydroxyethoxy)-1-methyl-;5-[(4-Bromo-2-fluorophenyl)amino]-4-fluoro-N-(2-hydroxyethoxy)-1-methyl-1H-benzimidazole-6-carboxamide Binimetinib (MEK162, ARRY-162, ARRY-438162);ARRY-438162 5-[(4-Bromo-2-fluorophenyl)amino]-4-fluoro-N-(2-hydroxyethoxy)-1-methyl-1H-benzimidazole-6-carboxamide;Binimetinib
30 prices
Selected condition：
Brand
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- Biorbyt Ltd
- Biosynth Carbosynth
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- DC Chemicals
- Matrix Scientific
- Medical Isotopes, Inc.
- Sigma-Aldrich
Package
- 5MG
- 10mg
- 20mg
- 50mg
- 100mg
- 200mg
- 250mg
- 1000mg
- 1G
- 5g
- ManufacturerAK Scientific
- Product numberY1468
- Product descriptionMEK162
- Packaging10mg
- Price$138
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0001469
- Product descriptionMEK-162 95.00%
- Packaging5MG
- Price$168.3
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0001469
- Product descriptionMEK-162 95.00%
- Packaging1G
- Price$1659
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA1947
- Product descriptionMEK162(ARRY-162,ARRY-438162)
- Packaging10mg
- Price$65
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA1947
- Product descriptionMEK162(ARRY-162,ARRY-438162)
- Packaging50mg
- Price$150
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA1947
- Product descriptionMEK162(ARRY-162,ARRY-438162)
- Packaging100mg
- Price$240
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberCFN60181
- Product descriptionBinimetinib(MEK162) ≥98%
- Packaging20mg
- Price$168
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb180927
- Product descriptionMEK162(Binimetinib) >98%
- Packaging100mg
- Price$606.9
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb180927
- Product descriptionMEK162(Binimetinib) >98%
- Packaging250mg
- Price$912.9
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb180927
- Product descriptionMEK162(Binimetinib) >98%
- Packaging1000mg
- Price$1949.9
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFM65077
- Product descriptionMEK162
- Packaging10mg
- Price$85
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFM65077
- Product descriptionMEK162
- Packaging50mg
- Price$298
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number16996
- Product descriptionBinimetinib ≥98%
- Packaging5mg
- Price$57
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number16996
- Product descriptionBinimetinib ≥98%
- Packaging10mg
- Price$107
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number16996
- Product descriptionBinimetinib ≥98%
- Packaging50mg
- Price$437
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number16996
- Product descriptionBinimetinib ≥98%
- Packaging100mg
- Price$765
- Updated2024-03-01
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | Y1468 | MEK162 | 10mg | $138 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | KIN0001469 | MEK-162 95.00% | 5MG | $168.3 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | KIN0001469 | MEK-162 95.00% | 1G | $1659 | 2021-12-16 | Buy |
| ApexBio Technology | A1947 | MEK162(ARRY-162,ARRY-438162) | 10mg | $65 | 2021-12-16 | Buy |
| ApexBio Technology | A1947 | MEK162(ARRY-162,ARRY-438162) | 50mg | $150 | 2021-12-16 | Buy |
| ApexBio Technology | A1947 | MEK162(ARRY-162,ARRY-438162) | 100mg | $240 | 2021-12-16 | Buy |
| Arctom | CFN60181 | Binimetinib(MEK162) ≥98% | 20mg | $168 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb180927 | MEK162(Binimetinib) >98% | 100mg | $606.9 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb180927 | MEK162(Binimetinib) >98% | 250mg | $912.9 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb180927 | MEK162(Binimetinib) >98% | 1000mg | $1949.9 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FM65077 | MEK162 | 10mg | $85 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FM65077 | MEK162 | 50mg | $298 | 2021-12-16 | Buy |
| Cayman Chemical | 16996 | Binimetinib ≥98% | 5mg | $57 | 2024-03-01 | Buy |
| Cayman Chemical | 16996 | Binimetinib ≥98% | 10mg | $107 | 2024-03-01 | Buy |
| Cayman Chemical | 16996 | Binimetinib ≥98% | 50mg | $437 | 2024-03-01 | Buy |
| Cayman Chemical | 16996 | Binimetinib ≥98% | 100mg | $765 | 2024-03-01 | Buy |
Properties
Melting point :>203oC (dec.)
Density :1.67
storage temp. :-20°C
solubility :Soluble in DMSO (up to at least 25 mg/ml)
pka :14.20±0.10(Predicted)
form :solid
color :White
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
Density :1.67
storage temp. :-20°C
solubility :Soluble in DMSO (up to at least 25 mg/ml)
pka :14.20±0.10(Predicted)
form :solid
color :White
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
Safety Information
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| Signal word: | Danger | |||||||||||||||||||||
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Description
Binimetinib is an orally bioavailable inhibitor of MEK1/2 (IC50 = 12 nM). It has been found to inhibit ERK phosphorylation in various cancer cell lines (IC50s ≥ 5 nM). This compound is efficacious in several xenograft tumor models in mice, including those bearing K-Ras or B-Raf mutations, and has been characterized in clinical studies using patients with N-Ras melanoma, non-small cell lung cancer, or biliary tract cancer.Related product price
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