Brigatinib
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- $5 - $1504.5
- Product name: Brigatinib
- CAS: 1197953-54-0
- MF: C29H39ClN7O2P
- MW: 584.09
- EINECS:1592732-453-0
- MDL Number:MFCD29472221
- Synonyms:Brigatinib;Brigatinib, AP26113;5-Chloro-N4-[2-(dimethylphosphinyl)phenyl]-N2-[2-methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]-2,4-pyrimidinediamine;atinib;Bri atinib ;2,4-Pyrimidinediamine, 5-chloro-N4-[2-(dimethylphosphinyl)phenyl]-N2-[2-methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]-;Brigatinib USP/EP/BP;1197953-54-0 Brigatinib
55 prices
Selected condition：
Brand
- ACHEMBLOCK
- Adipogen Life Sciences
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- Arctom
- AvaChem
- Axon Medchem
- Biorbyt Ltd
- Biosynth
- Cayman Chemical
- ChemScene
- Crysdot
- DC Chemicals
- TRC
Package
- 10mM*1mLinDMSO
- 1mg
- 5mg
- 10mg
- 25mg
- 50mg
- 100MG
- 250mg
- 500mg
- 1G
- 5G
- ManufacturerACHEMBLOCK
- Product numberL13974
- Product descriptionBrigatinib 98%
- Packaging5G
- Price$110
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberL13974
- Product descriptionBrigatinib 98%
- Packaging1G
- Price$40
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberL13974
- Product descriptionBrigatinib 98%
- Packaging100MG
- Price$15
- Updated2026-05-27
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberCDX-B0374-M005
- Product descriptionBrigatinib ≥98%(HPLC)
- Packaging5mg
- Price$79
- Updated2026-05-06
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberCDX-B0374-M025
- Product descriptionBrigatinib ≥98%(HPLC)
- Packaging25mg
- Price$316
- Updated2026-05-06
- Buy
- ManufacturerAK Scientific
- Product number9856BB
- Product descriptionBrigatinib
- Packaging100mg
- Price$239
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number9856BB
- Product descriptionBrigatinib
- Packaging50mg
- Price$171
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number9856BB
- Product descriptionBrigatinib
- Packaging500mg
- Price$522
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA151843
- Product description(2-((5-Chloro-2-((2-methoxy-4-(4-(4-methylpiperazin-1-yl)piperidin-1-yl)phenyl)amino)pyrimidin-4-yl)amino)phenyl)dimethylphosphineoxide 98+%
- Packaging5g
- Price$110
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA151843
- Product description(2-((5-Chloro-2-((2-methoxy-4-(4-(4-methylpiperazin-1-yl)piperidin-1-yl)phenyl)amino)pyrimidin-4-yl)amino)phenyl)dimethylphosphineoxide 98+%
- Packaging50mg
- Price$5
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA151843
- Product description(2-((5-Chloro-2-((2-methoxy-4-(4-(4-methylpiperazin-1-yl)piperidin-1-yl)phenyl)amino)pyrimidin-4-yl)amino)phenyl)dimethylphosphineoxide 98+%
- Packaging100mg
- Price$8
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA151843
- Product description(2-((5-Chloro-2-((2-methoxy-4-(4-(4-methylpiperazin-1-yl)piperidin-1-yl)phenyl)amino)pyrimidin-4-yl)amino)phenyl)dimethylphosphineoxide 98+%
- Packaging250mg
- Price$13
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA151843
- Product description(2-((5-Chloro-2-((2-methoxy-4-(4-(4-methylpiperazin-1-yl)piperidin-1-yl)phenyl)amino)pyrimidin-4-yl)amino)phenyl)dimethylphosphineoxide 98+%
- Packaging1g
- Price$32
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0028650
- Product descriptionBRIGATINIB 95.00%
- Packaging5MG
- Price$499.63
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberHY-12857
- Product descriptionBrigatinib 99.98%
- Packaging100mg
- Price$372
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-12857
- Product descriptionBrigatinib 99.98%
- Packaging5mg
- Price$77
- Updated2026-05-26
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| ACHEMBLOCK | L13974 | Brigatinib 98% | 5G | $110 | 2026-05-27 | Buy |
| ACHEMBLOCK | L13974 | Brigatinib 98% | 1G | $40 | 2026-05-27 | Buy |
| ACHEMBLOCK | L13974 | Brigatinib 98% | 100MG | $15 | 2026-05-27 | Buy |
| Adipogen Life Sciences | CDX-B0374-M005 | Brigatinib ≥98%(HPLC) | 5mg | $79 | 2026-05-06 | Buy |
| Adipogen Life Sciences | CDX-B0374-M025 | Brigatinib ≥98%(HPLC) | 25mg | $316 | 2026-05-06 | Buy |
| AK Scientific | 9856BB | Brigatinib | 100mg | $239 | 2021-12-16 | Buy |
| AK Scientific | 9856BB | Brigatinib | 50mg | $171 | 2021-12-16 | Buy |
| AK Scientific | 9856BB | Brigatinib | 500mg | $522 | 2021-12-16 | Buy |
| Ambeed | A151843 | (2-((5-Chloro-2-((2-methoxy-4-(4-(4-methylpiperazin-1-yl)piperidin-1-yl)phenyl)amino)pyrimidin-4-yl)amino)phenyl)dimethylphosphineoxide 98+% | 5g | $110 | 2021-12-16 | Buy |
| Ambeed | A151843 | (2-((5-Chloro-2-((2-methoxy-4-(4-(4-methylpiperazin-1-yl)piperidin-1-yl)phenyl)amino)pyrimidin-4-yl)amino)phenyl)dimethylphosphineoxide 98+% | 50mg | $5 | 2021-12-16 | Buy |
| Ambeed | A151843 | (2-((5-Chloro-2-((2-methoxy-4-(4-(4-methylpiperazin-1-yl)piperidin-1-yl)phenyl)amino)pyrimidin-4-yl)amino)phenyl)dimethylphosphineoxide 98+% | 100mg | $8 | 2021-12-16 | Buy |
| Ambeed | A151843 | (2-((5-Chloro-2-((2-methoxy-4-(4-(4-methylpiperazin-1-yl)piperidin-1-yl)phenyl)amino)pyrimidin-4-yl)amino)phenyl)dimethylphosphineoxide 98+% | 250mg | $13 | 2021-12-16 | Buy |
| Ambeed | A151843 | (2-((5-Chloro-2-((2-methoxy-4-(4-(4-methylpiperazin-1-yl)piperidin-1-yl)phenyl)amino)pyrimidin-4-yl)amino)phenyl)dimethylphosphineoxide 98+% | 1g | $32 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0028650 | BRIGATINIB 95.00% | 5MG | $499.63 | 2021-12-16 | Buy |
| Arctom | HY-12857 | Brigatinib 99.98% | 100mg | $372 | 2026-05-26 | Buy |
| Arctom | HY-12857 | Brigatinib 99.98% | 5mg | $77 | 2026-05-26 | Buy |
Properties
Melting point :>203°C (dec.)
Boiling point :781.8±70.0 °C(Predicted)
Density :1.31±0.1 g/cm3(Predicted)
storage temp. :-20°C
solubility :Soluble in DMSO (1 mg/ml with warming)
form :solid
pka :8.14±0.42(Predicted)
color :White to off-white
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
InChIKey :AILRADAXUVEEIR-UHFFFAOYSA-N
SMILES :C1(NC2=CC=C(N3CCC(N4CCN(C)CC4)CC3)C=C2OC)=NC=C(Cl)C(NC2=CC=CC=C2P(C)(C)=O)=N1
CAS DataBase Reference :1197953-54-0
Boiling point :781.8±70.0 °C(Predicted)
Density :1.31±0.1 g/cm3(Predicted)
storage temp. :-20°C
solubility :Soluble in DMSO (1 mg/ml with warming)
form :solid
pka :8.14±0.42(Predicted)
color :White to off-white
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
InChIKey :AILRADAXUVEEIR-UHFFFAOYSA-N
SMILES :C1(NC2=CC=C(N3CCC(N4CCN(C)CC4)CC3)C=C2OC)=NC=C(Cl)C(NC2=CC=CC=C2P(C)(C)=O)=N1
CAS DataBase Reference :1197953-54-0
Safety Information
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Description
Brigatinib is a small molecule inhibitor of both ALK and EGFR [195]. In preclinical models, “triple-mutant EGFR”-positive cells (activating EGFR mutation/ T790M/C797S) responded to the combination of brigatinib with an anti-EGFR monoclonal antibody, cetuximab or panitumumab [196]. Single-agent activity of brigatinib in a phase I/II trial was only 5% [197], possibly compounded by low plasma concentrations [196], but the addition of an anti-EGFR monoclonal antibody remains to be clinically tested. The preclinical data with brigatinib and EAI045in laboratory models with a C797S mutation demonstrate that combination therapies with an anti-EGFR monoclonal antibody may lead to overcoming resistance to osimertinib.More related product prices
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Suppliers and manufacturers
Enki Biopharmaceuticals(Shanghai) Limited
Jinan Chuanbei Biotechnology Co., Ltd
Shanghai Famo Bio-chemical Technology Company Ltd.
Scinova Biotech(Guangzhou) Co., Ltd.
Shanghai Peiling Biological Technology Co., LTD
Shanghai Boyle Chemical Co., Ltd.
ChemFuture PharmaTech (Jiangsu) Ltd
Chembest Research Laboratories Limited
Adamas Reagent, Ltd.
Suzhou Ryan Pharmaceutical Technology Co., Ltd.