Capmatinib
|
- $14 - $2409
- Product name: Capmatinib
- CAS: 1029712-80-8
- MF: C23H17FN6O
- MW: 412.42
- EINECS:813-241-9
- MDL Number:MFCD18633285
- Synonyms:INCB028060;CapMatinib (INCB28060);CapMatinib;NC280 BenzaMide,2-fluoro-N-Methyl-4-[7-(6-quinolinylMethyl)iMidazo[1,2-b][1,2,4]triazin-2-yl]-;NVP-INC280;2-Fluoro-N-methyl-4-[7-[(quinolin-6-yl)methyl]imidazo[1,2-b]-[1,2,4]triazin-2-yl]benzamide Capmatinib (INCB28060);INCB28060, INC280;BenzaMide, 2-fluoro-N-Methyl-4-[7-(6-quinolinylMethyl)iMidazo[1,2-b][1,2,4]triazin-2-yl]- INCB28060
67 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- Axon Medchem
- Biorbyt Ltd
- Biosynth
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- DC Chemicals
- Matrix Scientific
Package
- 10mM(in1mLDMSO)
- 1mg
- 5mg
- 10mM*1mLinDMSO
- 10mg
- 20mg
- 25MG
- 0.025g
- 0.05g
- 50mg
- 100mg
- 0.1g
- 200mg
- 250mg
- 0.25g
- 500mg
- 0.5g
- 1g
- 1000mg
- 5g
- 10g
- 50.00g
- 100.00g
- 250.00g
- Manufactureraablocks
- Product numberAA003A97
- Product description2-Fluoro-N-methyl-4-[7-(6-quinolinylmethyl)imidazo[1,2-b][1,2,4]triazin-2-yl]benzamide 98%
- Packaging10mg
- Price$45
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA003A97
- Product description2-Fluoro-N-methyl-4-[7-(6-quinolinylmethyl)imidazo[1,2-b][1,2,4]triazin-2-yl]benzamide 99%
- Packaging1mg
- Price$14
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA003A97
- Product description2-Fluoro-N-methyl-4-[7-(6-quinolinylmethyl)imidazo[1,2-b][1,2,4]triazin-2-yl]benzamide 99%
- Packaging5mg
- Price$28
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA003A97
- Product description2-Fluoro-N-methyl-4-[7-(6-quinolinylmethyl)imidazo[1,2-b][1,2,4]triazin-2-yl]benzamide 99%
- Packaging50mg
- Price$64
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA003A97
- Product description2-Fluoro-N-methyl-4-[7-(6-quinolinylmethyl)imidazo[1,2-b][1,2,4]triazin-2-yl]benzamide 99%
- Packaging100mg
- Price$87
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA003A97
- Product description2-Fluoro-N-methyl-4-[7-(6-quinolinylmethyl)imidazo[1,2-b][1,2,4]triazin-2-yl]benzamide 95
- Packaging200mg
- Price$156
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA003A97
- Product description2-Fluoro-N-methyl-4-[7-(6-quinolinylmethyl)imidazo[1,2-b][1,2,4]triazin-2-yl]benzamide 99%
- Packaging250mg
- Price$181
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA003A97
- Product description2-Fluoro-N-methyl-4-[7-(6-quinolinylmethyl)imidazo[1,2-b][1,2,4]triazin-2-yl]benzamide 95%
- Packaging1g
- Price$693
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA003A97
- Product description2-Fluoro-N-methyl-4-[7-(6-quinolinylmethyl)imidazo[1,2-b][1,2,4]triazin-2-yl]benzamide 95%
- Packaging5g
- Price$2409
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberK12247
- Product descriptionINCB28060 98%
- Packaging5G
- Price$1050
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberK12247
- Product descriptionINCB28060 98%
- Packaging1G
- Price$350
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberK12247
- Product descriptionINCB28060 98%
- Packaging100MG
- Price$110
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberK12247
- Product descriptionINCB28060 98%
- Packaging25MG
- Price$35
- Updated2026-05-27
- Buy
- ManufacturerAK Scientific
- Product numberY0337
- Product description2-fluoro-N-methyl-4-(7-(quinolin-6-ylmethyl)imidazo[1,2-b][1,2,4]triazin-2-yl)benzamide
- Packaging50mg
- Price$205
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberY0337
- Product description2-fluoro-N-methyl-4-(7-(quinolin-6-ylmethyl)imidazo[1,2-b][1,2,4]triazin-2-yl)benzamide
- Packaging10mg
- Price$153
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberY0337
- Product description2-fluoro-N-methyl-4-(7-(quinolin-6-ylmethyl)imidazo[1,2-b][1,2,4]triazin-2-yl)benzamide
- Packaging100mg
- Price$259
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA003A97 | 2-Fluoro-N-methyl-4-[7-(6-quinolinylmethyl)imidazo[1,2-b][1,2,4]triazin-2-yl]benzamide 98% | 10mg | $45 | 2026-05-28 | Buy |
| aablocks | AA003A97 | 2-Fluoro-N-methyl-4-[7-(6-quinolinylmethyl)imidazo[1,2-b][1,2,4]triazin-2-yl]benzamide 99% | 1mg | $14 | 2026-05-28 | Buy |
| aablocks | AA003A97 | 2-Fluoro-N-methyl-4-[7-(6-quinolinylmethyl)imidazo[1,2-b][1,2,4]triazin-2-yl]benzamide 99% | 5mg | $28 | 2026-05-28 | Buy |
| aablocks | AA003A97 | 2-Fluoro-N-methyl-4-[7-(6-quinolinylmethyl)imidazo[1,2-b][1,2,4]triazin-2-yl]benzamide 99% | 50mg | $64 | 2026-05-28 | Buy |
| aablocks | AA003A97 | 2-Fluoro-N-methyl-4-[7-(6-quinolinylmethyl)imidazo[1,2-b][1,2,4]triazin-2-yl]benzamide 99% | 100mg | $87 | 2026-05-28 | Buy |
| aablocks | AA003A97 | 2-Fluoro-N-methyl-4-[7-(6-quinolinylmethyl)imidazo[1,2-b][1,2,4]triazin-2-yl]benzamide 95 | 200mg | $156 | 2026-05-28 | Buy |
| aablocks | AA003A97 | 2-Fluoro-N-methyl-4-[7-(6-quinolinylmethyl)imidazo[1,2-b][1,2,4]triazin-2-yl]benzamide 99% | 250mg | $181 | 2026-05-28 | Buy |
| aablocks | AA003A97 | 2-Fluoro-N-methyl-4-[7-(6-quinolinylmethyl)imidazo[1,2-b][1,2,4]triazin-2-yl]benzamide 95% | 1g | $693 | 2026-05-28 | Buy |
| aablocks | AA003A97 | 2-Fluoro-N-methyl-4-[7-(6-quinolinylmethyl)imidazo[1,2-b][1,2,4]triazin-2-yl]benzamide 95% | 5g | $2409 | 2026-05-28 | Buy |
| ACHEMBLOCK | K12247 | INCB28060 98% | 5G | $1050 | 2026-05-27 | Buy |
| ACHEMBLOCK | K12247 | INCB28060 98% | 1G | $350 | 2026-05-27 | Buy |
| ACHEMBLOCK | K12247 | INCB28060 98% | 100MG | $110 | 2026-05-27 | Buy |
| ACHEMBLOCK | K12247 | INCB28060 98% | 25MG | $35 | 2026-05-27 | Buy |
| AK Scientific | Y0337 | 2-fluoro-N-methyl-4-(7-(quinolin-6-ylmethyl)imidazo[1,2-b][1,2,4]triazin-2-yl)benzamide | 50mg | $205 | 2021-12-16 | Buy |
| AK Scientific | Y0337 | 2-fluoro-N-methyl-4-(7-(quinolin-6-ylmethyl)imidazo[1,2-b][1,2,4]triazin-2-yl)benzamide | 10mg | $153 | 2021-12-16 | Buy |
| AK Scientific | Y0337 | 2-fluoro-N-methyl-4-(7-(quinolin-6-ylmethyl)imidazo[1,2-b][1,2,4]triazin-2-yl)benzamide | 100mg | $259 | 2021-12-16 | Buy |
Properties
Melting point :>250°C (dec.)
Density :1.40
vapor pressure :0-0Pa at 20-25℃
storage temp. :-20°C Freezer, Under inert atmosphere
solubility :DMSO (Slightly), Methanol (Slightly)
pka :13.82±0.46(Predicted)
form :Solid
color :Pale Yellow to Light Yellow
InChI :InChI=1S/C23H17FN6O/c1-25-22(31)18-6-5-16(11-19(18)24)21-13-28-23-27-12-17(30(23)29-21)10-14-4-7-20-15(9-14)3-2-8-26-20/h2-9,11-13H,10H2,1H3,(H,25,31)
InChIKey :LIOLIMKSCNQPLV-UHFFFAOYSA-N
SMILES :C(NC)(=O)C1=CC=C(C2=NN3C(CC4=CC=C5C(=C4)C=CC=N5)=CN=C3N=C2)C=C1F
LogP :1.6-2.2 at 35℃ and pH7-9
Density :1.40
vapor pressure :0-0Pa at 20-25℃
storage temp. :-20°C Freezer, Under inert atmosphere
solubility :DMSO (Slightly), Methanol (Slightly)
pka :13.82±0.46(Predicted)
form :Solid
color :Pale Yellow to Light Yellow
InChI :InChI=1S/C23H17FN6O/c1-25-22(31)18-6-5-16(11-19(18)24)21-13-28-23-27-12-17(30(23)29-21)10-14-4-7-20-15(9-14)3-2-8-26-20/h2-9,11-13H,10H2,1H3,(H,25,31)
InChIKey :LIOLIMKSCNQPLV-UHFFFAOYSA-N
SMILES :C(NC)(=O)C1=CC=C(C2=NN3C(CC4=CC=C5C(=C4)C=CC=N5)=CN=C3N=C2)C=C1F
LogP :1.6-2.2 at 35℃ and pH7-9
Safety Information
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| Signal word: | Warning | |||||||||||||||||||||||||||||||||||
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Description
INCB 28060 is an inhibitor of heptatocyte growth factor receptor (HGFR, also known as c-Met), potently blocking in vitro kinase activity (IC50 = 0.13 nM) as well as constitutive or HGF-stimulated activity in cells (IC50 values range from 0.3 to 1.1 nM). It blocks cell proliferation and migration or induces apoptosis in different types of cancer cells. INCB 28060 is orally bioavailable and inhibits the growth of HGFR-dependent tumors in mice. It also improves efficacy of gemcitabine in a mouse pancreatic cancer model and reduces migration and adhesion in ovarian cancer cell models.Related product price
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Suppliers and manufacturers
Tianjin Zhongcheng Mingyuan Technology Co., Ltd.
Suzhou Ryan Pharmaceutical Technology Co., Ltd.
Shanghai Boyle Chemical Co., Ltd.
Chembest Research Laboratories Limited
Jinan Trio PharmaTech Co., Ltd.
Dalian Meilun Biotech Co., Ltd.
T&W GROUP
Shanghai Topbiochem Technology Co., Ltd
NCE Biomedical Co.,Ltd.
Haoyuan Chemexpress Co., Ltd.