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ChemicalBook >> CAS DataBase List >> CAY10621

CAY10621

CAY10621 price.
  • $28 - $662
  • Product name: CAY10621
  • CAS: 120005-55-2
  • MF: C26H45NO4
  • MW: 435.64
  • EINECS:
  • MDL Number:MFCD18428021
  • Synonyms:CAY10621;2,2-Dimethyl-4S-(1-oxo-2-hexadecyn-1-yl)-1,1-dimethylethyl ester-3-oxazolidinecarboxylic acid;SKI 5C;SPHK1 Inhibitor 5C;YGBSGZPIDCXNEH-QFIPXVFZSA-N;3-Oxazolidinecarboxylic acid, 2,2-dimethyl-4-(1-oxo-2-hexadecyn-1-yl)-, 1,1-dimethylethyl ester, (4S)-;CAY10621 (SKI 5C);CAY10621 (SKI 5C), SPHK 1 inhibitor
Price11 Properties Safety Information Description
11 prices
Selected condition：
Brand
  • AK Scientific
  • American Custom Chemicals Corporation
  • Cayman Chemical
  • Sigma-Aldrich
  • TRC
Package
  • 1MG
  • 2.5mg
  • 5mg
  • 10mg
  • 25mg
  • ManufacturerAK Scientific
  • Product number1329AH
  • Product description2,2-Dimethyl-4S-(1-oxo-2-hexadecyn-1-yl)-1,1-dimethylethylester-3-oxazolidinecarboxylicacid
  • Packaging5mg
  • Price$228
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number1329AH
  • Product description2,2-Dimethyl-4S-(1-oxo-2-hexadecyn-1-yl)-1,1-dimethylethylester-3-oxazolidinecarboxylicacid
  • Packaging25mg
  • Price$596
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberCCH0005902
  • Product description2,2-DIMETHYL-4S-(1-OXO-2-HEXADECYN-1-YL)-1,1-DIMETHYLETHYL ESTER-3-OXAZOLIDINECARBOXYLIC ACID 95.00%
  • Packaging1MG
  • Price$131.25
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberCCH0005902
  • Product description2,2-DIMETHYL-4S-(1-OXO-2-HEXADECYN-1-YL)-1,1-DIMETHYLETHYL ESTER-3-OXAZOLIDINECARBOXYLIC ACID 95.00%
  • Packaging5MG
  • Price$498.86
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number13371
  • Product descriptionCAY10621 ≥98%
  • Packaging1mg
  • Price$28
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number13371
  • Product descriptionCAY10621 ≥98%
  • Packaging5mg
  • Price$117
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number13371
  • Product descriptionCAY10621 ≥98%
  • Packaging10mg
  • Price$207
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number13371
  • Product descriptionCAY10621 ≥98%
  • Packaging25mg
  • Price$448
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberS8326
  • Product descriptionSKI 5C ≥98% (HPLC)
  • Packaging5mg
  • Price$126
  • Updated2025-07-31
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberS8326
  • Product descriptionSKI 5C ≥98% (HPLC)
  • Packaging25mg
  • Price$662
  • Updated2023-01-07
  • Buy
  • ManufacturerTRC
  • Product numberS681730
  • Product descriptionSPHK1Inhibitor5C
  • Packaging2.5mg
  • Price$100
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 1329AH 2,2-Dimethyl-4S-(1-oxo-2-hexadecyn-1-yl)-1,1-dimethylethylester-3-oxazolidinecarboxylicacid 5mg $228 2021-12-16 Buy
AK Scientific 1329AH 2,2-Dimethyl-4S-(1-oxo-2-hexadecyn-1-yl)-1,1-dimethylethylester-3-oxazolidinecarboxylicacid 25mg $596 2021-12-16 Buy
American Custom Chemicals Corporation CCH0005902 2,2-DIMETHYL-4S-(1-OXO-2-HEXADECYN-1-YL)-1,1-DIMETHYLETHYL ESTER-3-OXAZOLIDINECARBOXYLIC ACID 95.00% 1MG $131.25 2021-12-16 Buy
American Custom Chemicals Corporation CCH0005902 2,2-DIMETHYL-4S-(1-OXO-2-HEXADECYN-1-YL)-1,1-DIMETHYLETHYL ESTER-3-OXAZOLIDINECARBOXYLIC ACID 95.00% 5MG $498.86 2021-12-16 Buy
Cayman Chemical 13371 CAY10621 ≥98% 1mg $28 2024-03-01 Buy
Cayman Chemical 13371 CAY10621 ≥98% 5mg $117 2024-03-01 Buy
Cayman Chemical 13371 CAY10621 ≥98% 10mg $207 2024-03-01 Buy
Cayman Chemical 13371 CAY10621 ≥98% 25mg $448 2024-03-01 Buy
Sigma-Aldrich S8326 SKI 5C ≥98% (HPLC) 5mg $126 2025-07-31 Buy
Sigma-Aldrich S8326 SKI 5C ≥98% (HPLC) 25mg $662 2023-01-07 Buy
TRC S681730 SPHK1Inhibitor5C 2.5mg $100 2021-12-16 Buy

Properties

Boiling point :519.0±60.0 °C(Predicted)
Density :0.985±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMF: 3 mg/ml; DMSO: 2 mg/ml; Ethanol: 2.5 mg/ml
form :oil
pka :-3.98±0.60(Predicted)
color :colorless to light brown
InChI :1S/C26H45NO4/c1-7-8-9-10-11-12-13-14-15-16-17-18-19-20-23(28)22-21-30-26(5,6)27(22)24(29)31-25(2,3)4/h22H,7-18,21H2,1-6H3/t22-/m0/s1
InChIKey :YGBSGZPIDCXNEH-QFIPXVFZSA-N
SMILES :CCCCCCCCCCCCCC#CC(=O)[C@@H]1COC(C)(C)N1C(=O)OC(C)(C)C

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

The sphingosine kinases (SPHK) phosphorylate sphingosine, producing the important lipid mediator sphingosine-1-phosphate (S1P). The two known kinases, SPHK 1 and SPHK 2, have different developmental and tissue expression patterns, suggesting that they have distinct physiological functions. Notably, SPHK 1 is overexpressed in several forms of cancer and inhibition of SPHK 1 inhibits tumor growth. CAY10621 is a selective inhibitor of SPHK 1, both in vitro (IC50 = 3.3 μM) and in U937 cells overexpressing human SPHK 1 (70% inhibition at 5 μM). It has no inhibitory effect on SPHK 2 either in vitro or in cells. Similarly, CAY10621 does not reduce the activity of protein kinase C (PKC) except at very high concentration (>75 μM).

Suppliers and manufacturers

TargetMol Chemicals Inc.
SKI 5C
$98.00 /1mg
SKI 5C CAS:120005-55-2
Aladdin Scientific
NANJING YINGWEN BIOTECHNOLOGY CO LTD BOC Sciences BOC Sciences Shanghai Hongye Biotechnology Co. Ltd ChemeGen(Shanghai) Biotechnology Co.,Ltd. Energy Chemical amyjet TargetMol Chemicals Inc.