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ChemicalBook >> CAS DataBase List >> 4,5-Dihydro-N-[4-[[4-(1-methylethoxy)phenyl]carbonyl]phenyl]-1H-imidazol-2-amine

4,5-Dihydro-N-[4-[[4-(1-methylethoxy)phenyl]carbonyl]phenyl]-1H-imidazol-2-amine

4,5-Dihydro-N-[4-[[4-(1-methylethoxy)phenyl]carbonyl]phenyl]-1H-imidazol-2-amine price.
4 prices
Selected condition:
Brand
  • Cayman Chemical
Package
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • ManufacturerCayman Chemical
  • Product number10005913
  • Product descriptionCAY10449 ≥98%
  • Packaging1mg
  • Price$65
  • Updated2026-04-30
  • Buy
  • ManufacturerCayman Chemical
  • Product number10005913
  • Product descriptionCAY10449 ≥98%
  • Packaging5mg
  • Price$279
  • Updated2026-04-30
  • Buy
  • ManufacturerCayman Chemical
  • Product number10005913
  • Product descriptionCAY10449 ≥98%
  • Packaging10mg
  • Price$493
  • Updated2026-04-30
  • Buy
  • ManufacturerCayman Chemical
  • Product number10005913
  • Product descriptionCAY10449 ≥98%
  • Packaging25mg
  • Price$1077
  • Updated2026-04-30
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Cayman Chemical 10005913 CAY10449 ≥98% 1mg $65 2026-04-30 Buy
Cayman Chemical 10005913 CAY10449 ≥98% 5mg $279 2026-04-30 Buy
Cayman Chemical 10005913 CAY10449 ≥98% 10mg $493 2026-04-30 Buy
Cayman Chemical 10005913 CAY10449 ≥98% 25mg $1077 2026-04-30 Buy

Properties

solubility :DMF: 2 mg/ml
DMF: PBS (pH 7.2)(1:1): .5 mg/ml
DMSO: 2 mg/ml

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

Recently, a series of relatively simple compounds were found to be high-affinity ligands and functional antagonists for the human IP (prostacyclin) receptor. CAY10449 is one of the more potent of these. CAY10449 antagonizes the carbaprostacyclin-induced activation of human neuroblastoma adenylate cyclase, blocking cyclic AMP accumulation in a dose-dependent manner. Likewise, it inhibits the binding of tritiated iloprost to rodent neuroblastoma cells with a Ki value of about 3 nM. Although CAY10449 was not tested in rats, the related compound CAY10441 shows significant analgesic activity in standard antinociceptive assays.

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