CCT241161
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- $68 - $869
- Product name: CCT241161
- CAS: 1163719-91-2
- MF: C28H27N7O3S
- MW: 541.62
- EINECS:-0
- MDL Number:
- Synonyms:CCT241161;Urea, N-[4-[(3,4-dihydro-3-oxopyrido[2,3-b]pyrazin-8-yl)oxy]-2-(methylthio)phenyl]-N'-[3-(1,1-dimethylethyl)-1-phenyl-1H-pyrazol-5-yl]-;N-[4-[(3,4-dihydro-3-oxopyrido[2,3-b]pyrazin-8-yl)oxy]-2-(methylthio)phenyl]-N'-[3-(1,1-dimethylethyl)-1-phenyl-1H-pyrazol-5-yl]-urea;1-(5-tert-butyl-2-phenylpyrazol-3-yl)-3-[2-methylsulfanyl-4-[(3-oxo-4H-pyrido[2,3-b]pyrazin-8-yl)oxy]phenyl]urea
6 prices
Selected condition：
Brand
- AK Scientific
- Cayman Chemical
Package
- 500μg
- 1mg
- 5mg
- 10mg
- ManufacturerAK Scientific
- Product number2404DF
- Product descriptionCID44132853
- Packaging1mg
- Price$233
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number2404DF
- Product descriptionCID44132853
- Packaging5mg
- Price$626
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number25536
- Product descriptionCCT241161 ≥98%
- Packaging500μg
- Price$68
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number25536
- Product descriptionCCT241161 ≥98%
- Packaging1mg
- Price$130
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number25536
- Product descriptionCCT241161 ≥98%
- Packaging5mg
- Price$502
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number25536
- Product descriptionCCT241161 ≥98%
- Packaging10mg
- Price$869
- Updated2024-03-01
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 2404DF | CID44132853 | 1mg | $233 | 2021-12-16 | Buy |
| AK Scientific | 2404DF | CID44132853 | 5mg | $626 | 2021-12-16 | Buy |
| Cayman Chemical | 25536 | CCT241161 ≥98% | 500μg | $68 | 2024-03-01 | Buy |
| Cayman Chemical | 25536 | CCT241161 ≥98% | 1mg | $130 | 2024-03-01 | Buy |
| Cayman Chemical | 25536 | CCT241161 ≥98% | 5mg | $502 | 2024-03-01 | Buy |
| Cayman Chemical | 25536 | CCT241161 ≥98% | 10mg | $869 | 2024-03-01 | Buy |
Properties
Density :1.36±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMSO: Soluble
form :A solid
pka :8.47±0.20(Predicted)
storage temp. :Store at -20°C
solubility :DMSO: Soluble
form :A solid
pka :8.47±0.20(Predicted)
Safety Information
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Description
CCT241161 is a novel orally available, pan-RAF inhibitor with anti-SRC activity. CCT241161 blocked growth of BRAF-mutant and NRAS-mutant melanoma cells, inhibiting MEK?–ERK, in vitro and in vivo. CCT241161 also prevented growth of xenografts derived from patient tumours with acquired or intrinsic resistance to BRAF and MEK inhibitors. BRAF and MEK inhibitors are effective in BRAF mutant melanoma, but most patients eventually relapse with acquired resistance, and others present intrinsic resistance to these drugs.Suppliers and manufacturers
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