CD437
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- $19 - $4340
- Product name: CD437
- CAS: 125316-60-1
- MF: C27H26O3
- MW: 398.49
- EINECS:200-258-5
- MDL Number:MFCD03106506
- Synonyms:2-naphthalenecarboxylicacid,6-(4-hydroxy-3-tricyclo(3.3.1.1(3,7))dec-1-ylphen ;6-(4-hydroxy-3-tricyclo(3.3.1.1(3,7))dec-1-ylphenyl)-2-naphthalenecarboxylic ;AHPN, 6-[3-(1-Adamantyl)-4-hydroxyphenyl]-2-naphthalene carboxylic acid;O-DesMethyl Adapalene;CD 437/AHPN;Adapalene IMpurity F;Apoptosis Activator VI, CD437/AHPN ;ADAP-IME
97 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- Biorbyt Ltd
- Biosynth
- Cayman Chemical
- ChemScene
- DC Chemicals
- Sigma-Aldrich
- Synthonix
- TCI Chemical
- TRC
Package
- 1mlx10mM(inDMSO)
- 1mg
- 2mg
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 250MG
- 1G
- 10mM*1mLinDMSO
- 10mM*1mLinDMSO(Solid+Solvent)
- 5G
- 10mM(in1mLDMSO)
- 10mM*1mLinDMSO(Solution)
- Manufactureraablocks
- Product numberAA000NEM
- Product descriptionCD-437 98%
- Packaging1mg
- Price$19
- Updated2026-05-25
- Buy
- Manufactureraablocks
- Product numberAA000NEM
- Product descriptionCD-437 98%
- Packaging5mg
- Price$41
- Updated2026-05-25
- Buy
- Manufactureraablocks
- Product numberAA000NEM
- Product descriptionCD-437 98%
- Packaging10mg
- Price$60
- Updated2026-05-25
- Buy
- Manufactureraablocks
- Product numberAA000NEM
- Product descriptionCD-437 ≥98%(HPLC)
- Packaging25mg
- Price$128
- Updated2026-05-25
- Buy
- Manufactureraablocks
- Product numberAA000NEM
- Product descriptionCD-437 ≥98%(HPLC)
- Packaging100mg
- Price$366
- Updated2026-05-25
- Buy
- ManufacturerACHEMBLOCK
- Product numberT90731
- Product description6-[3-(1-adamantyl)-4-hydroxyphenyl]naphthalene-2-carboxylic acid 95%
- Packaging250MG
- Price$395
- Updated2026-05-25
- Buy
- ManufacturerACHEMBLOCK
- Product numberT90731
- Product description6-[3-(1-adamantyl)-4-hydroxyphenyl]naphthalene-2-carboxylic acid 95%
- Packaging250MG
- Price$395
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberT90731
- Product description6-[3-(1-adamantyl)-4-hydroxyphenyl]naphthalene-2-carboxylic acid 95%
- Packaging1G
- Price$1025
- Updated2026-05-25
- Buy
- ManufacturerACHEMBLOCK
- Product numberT90731
- Product description6-[3-(1-adamantyl)-4-hydroxyphenyl]naphthalene-2-carboxylic acid 95%
- Packaging1G
- Price$1025
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberT90731
- Product description6-[3-(1-adamantyl)-4-hydroxyphenyl]naphthalene-2-carboxylic acid 95%
- Packaging5G
- Price$4340
- Updated2026-05-25
- Buy
- ManufacturerACHEMBLOCK
- Product numberT90731
- Product description6-[3-(1-adamantyl)-4-hydroxyphenyl]naphthalene-2-carboxylic acid 95%
- Packaging5G
- Price$4340
- Updated2026-05-27
- Buy
- ManufacturerAK Scientific
- Product number4426BA
- Product description6-[3-(1-Adamantyl)-4-hydroxyphenyl]-2-naphthalenecarboxylicAcid
- Packaging1g
- Price$2085
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA570556
- Product descriptionCD-437 98+%
- Packaging100mg
- Price$584
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA570556
- Product descriptionCD-437 98+%
- Packaging10mg
- Price$156
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA570556
- Product descriptionCD-437 98+%
- Packaging25mg
- Price$265
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA570556
- Product descriptionCD-437 98+%
- Packaging5mg
- Price$112
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA000NEM | CD-437 98% | 1mg | $19 | 2026-05-25 | Buy |
| aablocks | AA000NEM | CD-437 98% | 5mg | $41 | 2026-05-25 | Buy |
| aablocks | AA000NEM | CD-437 98% | 10mg | $60 | 2026-05-25 | Buy |
| aablocks | AA000NEM | CD-437 ≥98%(HPLC) | 25mg | $128 | 2026-05-25 | Buy |
| aablocks | AA000NEM | CD-437 ≥98%(HPLC) | 100mg | $366 | 2026-05-25 | Buy |
| ACHEMBLOCK | T90731 | 6-[3-(1-adamantyl)-4-hydroxyphenyl]naphthalene-2-carboxylic acid 95% | 250MG | $395 | 2026-05-25 | Buy |
| ACHEMBLOCK | T90731 | 6-[3-(1-adamantyl)-4-hydroxyphenyl]naphthalene-2-carboxylic acid 95% | 250MG | $395 | 2026-05-27 | Buy |
| ACHEMBLOCK | T90731 | 6-[3-(1-adamantyl)-4-hydroxyphenyl]naphthalene-2-carboxylic acid 95% | 1G | $1025 | 2026-05-25 | Buy |
| ACHEMBLOCK | T90731 | 6-[3-(1-adamantyl)-4-hydroxyphenyl]naphthalene-2-carboxylic acid 95% | 1G | $1025 | 2026-05-27 | Buy |
| ACHEMBLOCK | T90731 | 6-[3-(1-adamantyl)-4-hydroxyphenyl]naphthalene-2-carboxylic acid 95% | 5G | $4340 | 2026-05-25 | Buy |
| ACHEMBLOCK | T90731 | 6-[3-(1-adamantyl)-4-hydroxyphenyl]naphthalene-2-carboxylic acid 95% | 5G | $4340 | 2026-05-27 | Buy |
| AK Scientific | 4426BA | 6-[3-(1-Adamantyl)-4-hydroxyphenyl]-2-naphthalenecarboxylicAcid | 1g | $2085 | 2021-12-16 | Buy |
| Ambeed | A570556 | CD-437 98+% | 100mg | $584 | 2021-12-16 | Buy |
| Ambeed | A570556 | CD-437 98+% | 10mg | $156 | 2021-12-16 | Buy |
| Ambeed | A570556 | CD-437 98+% | 25mg | $265 | 2021-12-16 | Buy |
| Ambeed | A570556 | CD-437 98+% | 5mg | $112 | 2021-12-16 | Buy |
Properties
Melting point :271.6-276 °C
Boiling point :595.0±50.0 °C(Predicted)
Density :1.290
storage temp. :-20°C
solubility :DMSO: 26 mg/mL
form :solid
pka :4.17±0.30(Predicted)
color :yellow
InChI :1S/C27H26O3/c28-25-6-5-22(20-1-2-21-11-23(26(29)30)4-3-19(21)10-20)12-24(25)27-13-16-7-17(14-27)9-18(8-16)15-27/h1-6,10-12,16-18,28H,7-9,13-15H2,(H,29,30)
InChIKey :LDGIHZJOIQSHPB-UHFFFAOYSA-N
SMILES :OC(=O)c1ccc2cc(ccc2c1)-c3ccc(O)c(c3)C45CC6CC(CC(C6)C4)C5
Boiling point :595.0±50.0 °C(Predicted)
Density :1.290
storage temp. :-20°C
solubility :DMSO: 26 mg/mL
form :solid
pka :4.17±0.30(Predicted)
color :yellow
InChI :1S/C27H26O3/c28-25-6-5-22(20-1-2-21-11-23(26(29)30)4-3-19(21)10-20)12-24(25)27-13-16-7-17(14-27)9-18(8-16)15-27/h1-6,10-12,16-18,28H,7-9,13-15H2,(H,29,30)
InChIKey :LDGIHZJOIQSHPB-UHFFFAOYSA-N
SMILES :OC(=O)c1ccc2cc(ccc2c1)-c3ccc(O)c(c3)C45CC6CC(CC(C6)C4)C5
Safety Information
| Symbol(GHS): |
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| Signal word: | Warning | ||||||||||||||
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| Precautionary statements: |
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Description
CD437 is the prototypical adamantyl arotinoid of the retinoid-related molecule family that acts as a selective agonist of retinoic acid receptor (RAR)γ (Kds = 6.5 μM, 2.5 μM, and 77 nM for RARα, β, and γ, respectively). CD437 is cytotoxic to the acute myeloid leukemia cell line NB4 (EC50 = 0.17 μM), inducing DNA damage by producing DNA double strand breaks. CD437 also induces cell cycle arrest and apoptosis in various other cancer cells including melanoma, breast, non-small lung, and prostate cancer cells through RAR-dependent and -independent signaling pathways.More related product prices
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