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ChemicalBook >> CAS DataBase List >> COMBRETASTATIN A-4

COMBRETASTATIN A-4

$10 - $2880
Product name: COMBRETASTATIN A-4
CAS: 117048-59-6
MF: C18H20O5
MW: 316.35
EINECS:
MDL Number:MFCD03453309
Synonyms:(Z)-2-Methoxy-5-[2-(3,4,5-trimethoxyphenyl)ethenyl]phenol,3,4,5-Trimethoxy-3hydroxy-4methoxy-(Z)-stilbene,CS-A4;Combrestatin A4( 2-Methoxy-5-[2-(3,4,5-trimethoxy-phenyl)-vinyl]-phenol );(Z)-2-Methoxy-5-(3,4,5-trimethoxystyryl)phenol ,98%;2-Methoxy-5-[(Z)-2-(3,4,5-trimethoxyphenyl)ethenyl]phenol;3-[(Z)-2-(3,4,5-Trimethoxyphenyl)ethenyl]-6-methoxyphenol;5-[(Z)-2-(3,4,5-Trimethoxyphenyl)ethenyl]-2-methoxyphenol;(Z)-CombretastatinA4;2-Methoxy-5-[(1Z)-2-(3,4,5-trimethoxyphenyl)ethenyl]phenol

Price91 Properties Safety Information Description

91 prices

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Brand

aablocks
ACHEMBLOCK
Adipogen Life Sciences
AK Scientific
Ambeed
American Custom Chemicals Corporation
ApexBio Technology
Arctom
Axon Medchem
Biorbyt Ltd
Biosynth
Cayman Chemical
Chem-Impex
ChemScene
Crysdot
DC Chemicals
Matrix Scientific
Sigma-Aldrich
TCI Chemical
TRC
Usbiological

Package

50ug
10mM*1mLinDMSO(Solution)
10μg
100ug
1mg
2mg
5mg
10mg
20mg
25mg
50ul
50mg
100ul
100mg
100.00mg
200ul
250.00mg
250mg
10mM*1mLinDMSO(Solid+Solvent)
1g
1.00g
5G
10g

Manufactureraablocks
Product numberAA000DJW
Product descriptionCombretastatin A4 98%
Packaging25mg
Price$31
Updated2026-05-25
Buy

Manufactureraablocks
Product numberAA000DJW
Product descriptionCombretastatin A4 98%
Packaging100mg
Price$82
Updated2026-05-25
Buy

Manufactureraablocks
Product numberAA000DJW
Product descriptionCombretastatin A4 98%
Packaging250mg
Price$147
Updated2026-05-25
Buy

Manufactureraablocks
Product numberAA000DJW
Product descriptionCombretastatin A4 98%
Packaging1g
Price$381
Updated2026-05-25
Buy

Manufactureraablocks
Product numberAA000DJW
Product descriptionCombretastatin A4 98%
Packaging10mg
Price$20
Updated2026-05-25
Buy

Manufactureraablocks
Product numberAA000DJW
Product descriptionCombretastatin A4 98%
Packaging5mg
Price$15
Updated2026-05-25
Buy

Manufactureraablocks
Product numberAA000DJW
Product descriptionCombretastatin A4 98%
Packaging1mg
Price$10
Updated2026-05-25
Buy

ManufacturerACHEMBLOCK
Product numberR16018
Product descriptionCombretastatin A4 99%
Packaging100MG
Price$56
Updated2026-05-27
Buy

ManufacturerACHEMBLOCK
Product numberR16018
Product descriptionCombretastatin A4 99%
Packaging1G
Price$236
Updated2026-05-27
Buy

ManufacturerACHEMBLOCK
Product numberR16018
Product descriptionCombretastatin A4 99%
Packaging5G
Price$840
Updated2026-05-27
Buy

ManufacturerAdipogen Life Sciences
Product numberCDX-C0706-M050
Product descriptionCombretastatin A4 ≥98%(HPLC)
Packaging50mg
Price$480
Updated2026-05-06
Buy

ManufacturerAdipogen Life Sciences
Product numberCDX-C0706-M010
Product descriptionCombretastatin A4 ≥98%(HPLC)
Packaging10mg
Price$111
Updated2026-05-06
Buy

ManufacturerAK Scientific
Product numberY0443
Product descriptionCombretastatin A4
Packaging1g
Price$593
Updated2021-12-16
Buy

ManufacturerAmbeed
Product numberA300403
Product description(Z)-2-Methoxy-5-(3,4,5-trimethoxystyryl)phenol 98%
Packaging5g
Price$1056
Updated2021-12-16
Buy

ManufacturerAmbeed
Product numberA300403
Product description(Z)-2-Methoxy-5-(3,4,5-trimethoxystyryl)phenol 98%
Packaging1g
Price$310
Updated2021-12-16
Buy

ManufacturerAmbeed
Product numberA300403
Product description(Z)-2-Methoxy-5-(3,4,5-trimethoxystyryl)phenol 98%
Packaging100mg
Price$67
Updated2021-12-16
Buy

Manufacturer	Product number	Product description	Packaging	Price	Updated	Buy
aablocks	AA000DJW	Combretastatin A4 98%	25mg	$31	2026-05-25	Buy
aablocks	AA000DJW	Combretastatin A4 98%	100mg	$82	2026-05-25	Buy
aablocks	AA000DJW	Combretastatin A4 98%	250mg	$147	2026-05-25	Buy
aablocks	AA000DJW	Combretastatin A4 98%	1g	$381	2026-05-25	Buy
aablocks	AA000DJW	Combretastatin A4 98%	10mg	$20	2026-05-25	Buy
aablocks	AA000DJW	Combretastatin A4 98%	5mg	$15	2026-05-25	Buy
aablocks	AA000DJW	Combretastatin A4 98%	1mg	$10	2026-05-25	Buy
ACHEMBLOCK	R16018	Combretastatin A4 99%	100MG	$56	2026-05-27	Buy
ACHEMBLOCK	R16018	Combretastatin A4 99%	1G	$236	2026-05-27	Buy
ACHEMBLOCK	R16018	Combretastatin A4 99%	5G	$840	2026-05-27	Buy
Adipogen Life Sciences	CDX-C0706-M050	Combretastatin A4 ≥98%(HPLC)	50mg	$480	2026-05-06	Buy
Adipogen Life Sciences	CDX-C0706-M010	Combretastatin A4 ≥98%(HPLC)	10mg	$111	2026-05-06	Buy
AK Scientific	Y0443	Combretastatin A4	1g	$593	2021-12-16	Buy
Ambeed	A300403	(Z)-2-Methoxy-5-(3,4,5-trimethoxystyryl)phenol 98%	5g	$1056	2021-12-16	Buy
Ambeed	A300403	(Z)-2-Methoxy-5-(3,4,5-trimethoxystyryl)phenol 98%	1g	$310	2021-12-16	Buy
Ambeed	A300403	(Z)-2-Methoxy-5-(3,4,5-trimethoxystyryl)phenol 98%	100mg	$67	2021-12-16	Buy

Next Last

Properties

Melting point :84.5-85.5°C
Boiling point :490.3±45.0 °C(Predicted)
Density :1.184±0.06 g/cm3(Predicted)
storage temp. :-20°C
solubility :DMSO: >10mg/mL
pka :9.65±0.10(Predicted)
form :powder
color :off-white
Merck :14,2494
InChI :InChI=1S/C18H20O5/c1-20-15-8-7-12(9-14(15)19)5-6-13-10-16(21-2)18(23-4)17(11-13)22-3/h5-11,19H,1-4H3/b6-5-
InChIKey :HVXBOLULGPECHP-WAYWQWQTSA-N
SMILES :C1(O)=CC(/C=C\C2=CC(OC)=C(OC)C(OC)=C2)=CC=C1OC

Safety Information

Symbol(GHS):

Signal word:

Danger

Hazard statements:

Code	Hazard statements	Hazard class	Category	Signal word	Pictogram	P-Codes
H318	Causes serious eye damage	Serious eye damage/eye irritation	Category 1	Danger		P280, P305+P351+P338, P310

Precautionary statements:

P261	Avoid breathing dust/fume/gas/mist/vapours/spray.
P280	Wear protective gloves/protective clothing/eye protection/face protection.
P301+P310	IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P305+P351+P338	IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Combrestatin A4 (CA4) is a potent inhibitor of tubulin polymerization and displays strong inhibitory activity on tumor cell growth. CA4 was shown to impede tumor growth in several cell lines including IMR32 (neuroblastoma), Hs746T (gastric carcinoma), CFPAC-1 (pancreatic carcinoma), and MCF-7 (breast cancer) with IC50 values of 2.16, 5.20, 3.46, and 18.47 nM, respectively. CA4 inhibits tubulin polymerization with an IC₅₀ value of 2.2 μM. Combrestatin A4 is an inhibitor of β Tubulin.

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Suppliers and manufacturers

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COMBRETASTATIN A-4

Properties

Safety Information

Description

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