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ChemicalBook >> CAS DataBase List >> CUCURBITACIN B

CUCURBITACIN B

CUCURBITACIN B price.
  • $37 - $1339.8
  • Product name: CUCURBITACIN B
  • CAS: 6199-67-3
  • MF: C32H46O8
  • MW: 558.7
  • EINECS:
  • MDL Number:MFCD07778083
  • Synonyms:(2beta,9beta,10alpha,16alpha,23e)-thyl ;19-nor-9-beta,10-alpha-lanosta-5,23-diene-3,11,22-trione,2-beta,16-alpha,20,25 ;19-nor-9beta,10alpha-lanosta-5,23-diene-3,11,22-trione,2beta,16alpha,20,25-tet ;19-norlanosta-5,23-diene-3,11,22-trione,25-(acetyloxy)-2,16,20-trihydroxy-9-me ;25-(acetyloxy)-2,16,20-trihydroxy-9-methyl-19-norlanosta-5,23-diene-3,11,22-tr ;Cucurbitacin B hydrate;cucurbitacineb ;AMARINE
36 prices
Selected condition:
Brand
  • Adipogen Life Sciences
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Arctom
  • AvaChem
  • Biorbyt Ltd
  • Biosynth Carbosynth
  • Cayman Chemical
  • Chem-Impex
  • ChemScene
  • DC Chemicals
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • TCI Chemical
  • TRC
  • Usbiological
Package
  • 1mg
  • 5mg
  • 10MG
  • 20mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • ManufacturerAdipogen Life Sciences
  • Product numberAG-CN2-0472-M025
  • Product descriptionCucurbitacin B ≥98%(HPLC)
  • Packaging25mg
  • Price$560
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberSHG0000914
  • Product description1,2-DIHYDRO-ALPHA-ELATERIN 98.00%
  • Packaging10MG
  • Price$1339.8
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberN2787
  • Product descriptionCucurbitacin B
  • Packaging20mg
  • Price$300
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberCFN99129
  • Product descriptionCucurbitacin B ≥98%
  • Packaging20mg
  • Price$100
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberSY076516
  • Product descriptionCucurbitacinB,98%,fromCucumismelo ≥97%
  • Packaging10mg
  • Price$150
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS021048
  • Product descriptionCucurbitacin B
  • Packaging10mg
  • Price$321
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number2359
  • Product descriptionCucurbitacin B
  • Packaging5mg
  • Price$90
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number2359
  • Product descriptionCucurbitacin B
  • Packaging10mg
  • Price$135
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number2359
  • Product descriptionCucurbitacin B
  • Packaging20mg
  • Price$205
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number2359
  • Product descriptionCucurbitacin B
  • Packaging100mg
  • Price$745
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb593851
  • Product descriptionCucurbitacin B
  • Packaging100mg
  • Price$472.6
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFC66008
  • Product descriptionCucurbitacin B
  • Packaging5mg
  • Price$95
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFC66008
  • Product descriptionCucurbitacin B
  • Packaging10mg
  • Price$160
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFC66008
  • Product descriptionCucurbitacin B
  • Packaging25mg
  • Price$350
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFC66008
  • Product descriptionCucurbitacin B
  • Packaging50mg
  • Price$600
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFC66008
  • Product descriptionCucurbitacin B
  • Packaging100mg
  • Price$1000
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Adipogen Life Sciences AG-CN2-0472-M025 Cucurbitacin B ≥98%(HPLC) 25mg $560 2021-12-16 Buy
American Custom Chemicals Corporation SHG0000914 1,2-DIHYDRO-ALPHA-ELATERIN 98.00% 10MG $1339.8 2021-12-16 Buy
ApexBio Technology N2787 Cucurbitacin B 20mg $300 2021-12-16 Buy
Arctom CFN99129 Cucurbitacin B ≥98% 20mg $100 2021-12-16 Buy
Arctom SY076516 CucurbitacinB,98%,fromCucumismelo ≥97% 10mg $150 2021-12-16 Buy
Arctom AS021048 Cucurbitacin B 10mg $321 2021-12-16 Buy
AvaChem 2359 Cucurbitacin B 5mg $90 2021-12-16 Buy
AvaChem 2359 Cucurbitacin B 10mg $135 2021-12-16 Buy
AvaChem 2359 Cucurbitacin B 20mg $205 2021-12-16 Buy
AvaChem 2359 Cucurbitacin B 100mg $745 2021-12-16 Buy
Biorbyt Ltd orb593851 Cucurbitacin B 100mg $472.6 2021-12-16 Buy
Biosynth Carbosynth FC66008 Cucurbitacin B 5mg $95 2021-12-16 Buy
Biosynth Carbosynth FC66008 Cucurbitacin B 10mg $160 2021-12-16 Buy
Biosynth Carbosynth FC66008 Cucurbitacin B 25mg $350 2021-12-16 Buy
Biosynth Carbosynth FC66008 Cucurbitacin B 50mg $600 2021-12-16 Buy
Biosynth Carbosynth FC66008 Cucurbitacin B 100mg $1000 2021-12-16 Buy

Properties

Melting point :184-186°
alpha :D25 +88° (c = 1.55 in ethanol)
Boiling point :546.74°C (rough estimate)
Density :1.0953 (rough estimate)
refractive index :1.4900 (estimate)
storage temp. :Keep in dark place,Sealed in dry,2-8°C
solubility :DMSO: soluble10mg/mL, clear
form :powder
pka :12.60±0.29(Predicted)
color :white to beige
λmax :290nm(EtOH)(lit.)
Merck :14,2614
Stability :Hygroscopic
InChIKey :IXQKXEUSCPEQRD-ALLWXVAWSA-N

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H300 Fatal if swallowed Acute toxicity,oral Category 1, 2 Danger GHS hazard pictograms P264, P270, P301+P310, P321, P330,P405, P501
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

Cucurbitacin B is a plant-derived triterpene that has the classic four-ring structure of mammalian steroids. It has diverse effects on mammalian cells, most notably inducing cell cycle arrest or apoptosis in a range of cancer cell lines. Cucurbitacin B inhibits the growth of several breast cancer cell lines (IC50s = 18-50 nM). It suppresses the growth of tumors developed from MDA-MB-231 and 4T-1 breast cancer cells in mice. Cucurbitacin B blocks the inflammatory response of macrophages treated with lipopolysaccharide. In Drosophila, it serves as an ecdysteroid receptor antagonist (Kd = 5 μM).

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