CYM-5478
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- $86 - $2400
- Product name: CYM-5478
- CAS: 870762-83-7
- MF: C21H19F3N2O2
- MW: 388.38
- EINECS:
- MDL Number:MFCD07342414
- Synonyms:CYM-5478;2(1H)-Pyridinone, 1-[2-[2,5-dimethyl-1-(phenylmethyl)-1H-pyrrol-3-yl]-2-oxoethyl]-5-(trifluoromethyl)-;1-[2-[2,5-dimethyl-1-(phenylmethyl)-1H-pyrrol-3-yl]-2-oxoethyl]-5-(trifluoromethyl)-2(1H)-pyridinone;1-[2-(1-benzyl-2,5-dimethyl-1H-pyrrol-3-yl)-2-oxoethyl]-5-(trifluoromethyl)-1,2-dihydropyridin-2-one;1-[2-(1-Benzyl-2,5-dimethylpyrrol-3-yl)-2-oxoethyl]-5-(trifluoromethyl) pyridin-2-one
23 prices
Selected condition:
Brand
- aablocks
- AK Scientific
- Arctom
- Cayman Chemical
- ChemScene
- DC Chemicals
Package
- 1mg
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 250mg
- 1g
- Manufactureraablocks
- Product numberAA01LIVA
- Product description1-[2-[2,5-Dimethyl-1-(phenylmethyl)-1H-pyrrol-3-yl]-2-oxoethyl]-5-(trifluoromethyl)-2(1H)-pyridinone ≥98%
- Packaging1mg
- Price$103
- Updated2026-05-30
- Buy
- Manufactureraablocks
- Product numberAA01LIVA
- Product description1-[2-[2,5-Dimethyl-1-(phenylmethyl)-1H-pyrrol-3-yl]-2-oxoethyl]-5-(trifluoromethyl)-2(1H)-pyridinone 98%byHPLC
- Packaging10mg
- Price$389
- Updated2026-05-30
- Buy
- Manufactureraablocks
- Product numberAA01LIVA
- Product description1-[2-[2,5-Dimethyl-1-(phenylmethyl)-1H-pyrrol-3-yl]-2-oxoethyl]-5-(trifluoromethyl)-2(1H)-pyridinone 98%byHPLC
- Packaging5mg
- Price$248
- Updated2026-05-30
- Buy
- Manufactureraablocks
- Product numberAA01LIVA
- Product description1-[2-[2,5-Dimethyl-1-(phenylmethyl)-1H-pyrrol-3-yl]-2-oxoethyl]-5-(trifluoromethyl)-2(1H)-pyridinone 98%byHPLC
- Packaging25mg
- Price$774
- Updated2026-05-30
- Buy
- Manufactureraablocks
- Product numberAA01LIVA
- Product description1-[2-[2,5-Dimethyl-1-(phenylmethyl)-1H-pyrrol-3-yl]-2-oxoethyl]-5-(trifluoromethyl)-2(1H)-pyridinone 98%byHPLC
- Packaging50mg
- Price$1287
- Updated2026-05-30
- Buy
- ManufacturerAK Scientific
- Product number8735CQ
- Product description1-[2-(1-Benzyl-2,5-dimethylpyrrol-3-yl)-2-oxoethyl]-5-(trifluoromethyl)pyridin-2-one
- Packaging1mg
- Price$201
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberHY-111253
- Product descriptionCYM-5478 99.44%
- Packaging1mg
- Price$86
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-111253
- Product descriptionCYM-5478 99.44%
- Packaging10mg
- Price$453
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-111253
- Product descriptionCYM-5478 99.44%
- Packaging50mg
- Price$1140
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-111253
- Product descriptionCYM-5478 99.44%
- Packaging25mg
- Price$814
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-111253
- Product descriptionCYM-5478 99.44%
- Packaging5mg
- Price$323
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-111253
- Product descriptionCYM-5478 99.44%
- Packaging100mg
- Price$1615
- Updated2026-05-26
- Buy
- ManufacturerCayman Chemical
- Product number29024
- Product descriptionCYM 5478 ≥98%
- Packaging1mg
- Price$103
- Updated2026-04-30
- Buy
- ManufacturerCayman Chemical
- Product number29024
- Product descriptionCYM 5478 ≥98%
- Packaging5mg
- Price$454
- Updated2026-04-30
- Buy
- ManufacturerChemScene
- Product numberCS-0034768
- Product descriptionCYM-5478 99.44%
- Packaging10mg
- Price$516
- Updated2026-06-04
- Buy
- ManufacturerChemScene
- Product numberCS-0034768
- Product descriptionCYM-5478 99.44%
- Packaging1mg
- Price$97
- Updated2026-06-04
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA01LIVA | 1-[2-[2,5-Dimethyl-1-(phenylmethyl)-1H-pyrrol-3-yl]-2-oxoethyl]-5-(trifluoromethyl)-2(1H)-pyridinone ≥98% | 1mg | $103 | 2026-05-30 | Buy |
| aablocks | AA01LIVA | 1-[2-[2,5-Dimethyl-1-(phenylmethyl)-1H-pyrrol-3-yl]-2-oxoethyl]-5-(trifluoromethyl)-2(1H)-pyridinone 98%byHPLC | 10mg | $389 | 2026-05-30 | Buy |
| aablocks | AA01LIVA | 1-[2-[2,5-Dimethyl-1-(phenylmethyl)-1H-pyrrol-3-yl]-2-oxoethyl]-5-(trifluoromethyl)-2(1H)-pyridinone 98%byHPLC | 5mg | $248 | 2026-05-30 | Buy |
| aablocks | AA01LIVA | 1-[2-[2,5-Dimethyl-1-(phenylmethyl)-1H-pyrrol-3-yl]-2-oxoethyl]-5-(trifluoromethyl)-2(1H)-pyridinone 98%byHPLC | 25mg | $774 | 2026-05-30 | Buy |
| aablocks | AA01LIVA | 1-[2-[2,5-Dimethyl-1-(phenylmethyl)-1H-pyrrol-3-yl]-2-oxoethyl]-5-(trifluoromethyl)-2(1H)-pyridinone 98%byHPLC | 50mg | $1287 | 2026-05-30 | Buy |
| AK Scientific | 8735CQ | 1-[2-(1-Benzyl-2,5-dimethylpyrrol-3-yl)-2-oxoethyl]-5-(trifluoromethyl)pyridin-2-one | 1mg | $201 | 2021-12-16 | Buy |
| Arctom | HY-111253 | CYM-5478 99.44% | 1mg | $86 | 2026-05-26 | Buy |
| Arctom | HY-111253 | CYM-5478 99.44% | 10mg | $453 | 2026-05-26 | Buy |
| Arctom | HY-111253 | CYM-5478 99.44% | 50mg | $1140 | 2026-05-26 | Buy |
| Arctom | HY-111253 | CYM-5478 99.44% | 25mg | $814 | 2026-05-26 | Buy |
| Arctom | HY-111253 | CYM-5478 99.44% | 5mg | $323 | 2026-05-26 | Buy |
| Arctom | HY-111253 | CYM-5478 99.44% | 100mg | $1615 | 2026-05-26 | Buy |
| Cayman Chemical | 29024 | CYM 5478 ≥98% | 1mg | $103 | 2026-04-30 | Buy |
| Cayman Chemical | 29024 | CYM 5478 ≥98% | 5mg | $454 | 2026-04-30 | Buy |
| ChemScene | CS-0034768 | CYM-5478 99.44% | 10mg | $516 | 2026-06-04 | Buy |
| ChemScene | CS-0034768 | CYM-5478 99.44% | 1mg | $97 | 2026-06-04 | Buy |
Properties
Boiling point :527.1±50.0 °C(Predicted)
Density :1.23±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMSO: soluble
form :A crystalline solid
pka :-2.22±0.70(Predicted)
color :White to off-white
Density :1.23±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMSO: soluble
form :A crystalline solid
pka :-2.22±0.70(Predicted)
color :White to off-white
Safety Information
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Description
CYM 5478 is a sphingosine-1-phosphate receptor 2 (S1P2) agonist (EC50 = 0.78 μM in a reporter assay). It is selective for S1P2 over S1P1 and S1P3-5 in a TGFα-shedding assay (EC50s = 119, 1,690, 1,950, >10,000, and >10,000 nM, respectively). CYM 5478 (0.1-10 μM) reduces serum starvation-induced decreases in C6 rat glioma cell viability. It also reduces accumulation of reactive oxygen species (ROS) and apoptosis induced by cisplatin in C6 cells when used at a concentration of 10 μM.Related product price
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