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ChemicalBook >> CAS DataBase List >> Cantharidin

Cantharidin

Cantharidin price.
  • $18.78 - $681.45
  • Product name: Cantharidin
  • CAS: 56-25-7
  • MF: C10H12O4
  • MW: 196.2
  • EINECS:200-263-3
  • MDL Number:MFCD00134968
  • Synonyms:(1r,2s,3r,6s)-1,2-dimethyl-3,6-epoxycyclohexane-1,2-dicarboxylic anhydride;CANTHARIDIN;dimethyl-3,6-epoxyperhydrophthalic anhydride;HEXAHYDRO-3A,7A-DIMETHYL-4,7-EPOXYISOBENZO-FURAN-1,3-DIONE;4,7-epoxyisobenzofuran-1,3-dione,hexahydro-3a,7a-dimethyl-,(3a-alpha,4-beta ;4,7-epoxyisobenzofuran-1,3-dione,hexahydro-3a,7a-dimethyl-,(3aalpha,4beta,7 ;4,7-epoxyisobenzofuran-1,3-dione,hexahydro-3a,7a-dimethyl-,(3aalpha,4beta,7be ;7aalpha)-bet
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  • Adipogen Life Sciences
  • AHH
  • AK Scientific
  • Alfa Aesar
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Arctom
  • Biorbyt Ltd
  • Biosynth Carbosynth
  • Cayman Chemical
  • Chem-Impex
  • DC Chemicals
  • Sigma-Aldrich
  • TCI Chemical
  • Tocris
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Package
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  • 100mg
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  • 1G
  • 1ml
  • ManufacturerAdipogen Life Sciences
  • Product numberCDX-C0643-M100
  • Product descriptionCantharidin ≥98%(HPLC)
  • Packaging100mg
  • Price$106
  • Updated2021-12-16
  • Buy
  • ManufacturerAdipogen Life Sciences
  • Product numberCDX-C0643-M500
  • Product descriptionCantharidin ≥98%(HPLC)
  • Packaging500mg
  • Price$424
  • Updated2021-12-16
  • Buy
  • ManufacturerAHH
  • Product numberMT-04372
  • Product descriptionCantharidin 98%
  • Packaging0.5g
  • Price$658
  • Updated2021-12-16
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  • ManufacturerAK Scientific
  • Product numberX1105
  • Product descriptionCantharidin
  • Packaging25mg
  • Price$73
  • Updated2021-12-16
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  • ManufacturerAlfa Aesar
  • Product numberJ61801
  • Product descriptionCantharidin, 98%
  • Packaging100mg
  • Price$284
  • Updated2024-03-01
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  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0001832
  • Product descriptionCANTHARIDIN 95.00%
  • Packaging25MG
  • Price$149.1
  • Updated2021-12-16
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  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0001832
  • Product descriptionCANTHARIDIN 95.00%
  • Packaging50MG
  • Price$653.68
  • Updated2021-12-16
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  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0001832
  • Product descriptionCANTHARIDIN 95.00%
  • Packaging1G
  • Price$681.45
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberN1686
  • Product descriptionCantharidin
  • Packaging20mg
  • Price$35
  • Updated2021-12-16
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  • ManufacturerArctom
  • Product numberCFN99790
  • Product descriptionCantharidin ≥98%
  • Packaging20mg
  • Price$40
  • Updated2021-12-16
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  • ManufacturerBiorbyt Ltd
  • Product numberorb545798
  • Product descriptionCantharidin >98%
  • Packaging20mg
  • Price$136
  • Updated2021-12-16
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  • ManufacturerBiorbyt Ltd
  • Product numberorb593805
  • Product descriptionCantharidin
  • Packaging20mg
  • Price$207.4
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb593805
  • Product descriptionCantharidin
  • Packaging100mg
  • Price$289
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb545798
  • Product descriptionCantharidin >98%
  • Packaging100mg
  • Price$323
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFC29633
  • Product descriptionCantharidin
  • Packaging25mg
  • Price$62.5
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFC29633
  • Product descriptionCantharidin
  • Packaging50mg
  • Price$100
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Adipogen Life Sciences CDX-C0643-M100 Cantharidin ≥98%(HPLC) 100mg $106 2021-12-16 Buy
Adipogen Life Sciences CDX-C0643-M500 Cantharidin ≥98%(HPLC) 500mg $424 2021-12-16 Buy
AHH MT-04372 Cantharidin 98% 0.5g $658 2021-12-16 Buy
AK Scientific X1105 Cantharidin 25mg $73 2021-12-16 Buy
Alfa Aesar J61801 Cantharidin, 98% 100mg $284 2024-03-01 Buy
American Custom Chemicals Corporation API0001832 CANTHARIDIN 95.00% 25MG $149.1 2021-12-16 Buy
American Custom Chemicals Corporation API0001832 CANTHARIDIN 95.00% 50MG $653.68 2021-12-16 Buy
American Custom Chemicals Corporation API0001832 CANTHARIDIN 95.00% 1G $681.45 2021-12-16 Buy
ApexBio Technology N1686 Cantharidin 20mg $35 2021-12-16 Buy
Arctom CFN99790 Cantharidin ≥98% 20mg $40 2021-12-16 Buy
Biorbyt Ltd orb545798 Cantharidin >98% 20mg $136 2021-12-16 Buy
Biorbyt Ltd orb593805 Cantharidin 20mg $207.4 2021-12-16 Buy
Biorbyt Ltd orb593805 Cantharidin 100mg $289 2021-12-16 Buy
Biorbyt Ltd orb545798 Cantharidin >98% 100mg $323 2021-12-16 Buy
Biosynth Carbosynth FC29633 Cantharidin 25mg $62.5 2021-12-16 Buy
Biosynth Carbosynth FC29633 Cantharidin 50mg $100 2021-12-16 Buy

Properties

Melting point :215-217 °C (lit.)
Boiling point :253.08°C (rough estimate)
Density :1.0357 (rough estimate)
refractive index :1.4699 (estimate)
storage temp. :2-8°C
solubility :Soluble in DMSO (25 mg/ml warm), acetone (8 mg/ml), ethanol (8 mg/ml warm), chloroform (1:65), ether (1:560), and ethyl acetate (1:150).
form :solution
color :white
Water Solubility :30mg/L(20 ºC)
Merck :14,1752
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 2 weeks.
InChIKey :DHZBEENLJMYSHQ-XCVPVQRUSA-N
LogP :-0.409 (est)
CAS DataBase Reference :56-25-7(CAS DataBase Reference)
IARC :3 (Vol. 10, Sup 7) 1987
NIST Chemistry Reference :Cantharidin(56-25-7)
EPA Substance Registry System :Cantharidin (56-25-7)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H300 Fatal if swallowed Acute toxicity,oral Category 1, 2 Danger GHS hazard pictograms P264, P270, P301+P310, P321, P330,P405, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Cantharidin is a natural toxicant of blister beetles. Cantharidin has been used as a medicinal agent for over 2000 years and is listed as a drug under the name of Mylabris in the medical monograph Materia Medica published in 77 AD. Some of the most ancient Chinese prescriptions (306–168 BC) refer to the use of Mylabris for the treatment of furuncles and piles.
Cantharidin can be used for topically (0.7%) treatment of warts, in which the skin under the wart blisters, thereby, lifting the wart off the skin. It is used to treat molluscum contagiosum. Cantharidin is a strong inhibitor of protein phosphatases types 1 (PP1) and 2A (PP2A), which are potentially novel targets for anticancer therapies. Thus, cantharidin is exploited as anticancer drugs. Cantharidin is shown to be cytotoxic to cancer cells and stimulatory on the bone marrow. The renal toxicity of this drug has prevented its use in mainstream oncology.

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