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ChemicalBook >> CAS DataBase List >> Cetilistat

Cetilistat

Cetilistat price.
  • $5 - $750
  • Product name: Cetilistat
  • CAS: 282526-98-1
  • MF: C25H39NO3
  • MW: 401.58
  • EINECS:1308068-626-2
  • MDL Number:MFCD09839697
  • Synonyms:cetilistat;Cetilistat(Alt-962);Cetilstat;2-(Hexadecycloxy)-6-methyl-4H-3,1-benzoxazin-4-one;4H-3,1-Benzoxazin-4-one,2-(hexadecyloxy)-6-Methyl-;Xinli orlistat;2-hexadecoxy-6-methyl-3,1-benzoxazin-4-one;Cetilistat (ATL-962)
29 prices
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Brand
  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Arctom
  • Biosynth Carbosynth
  • Chem-Impex
  • Crysdot
  • CSNpharm
  • Labseeker
  • TCI Chemical
  • TRC
  • Usbiological
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  • 1kg
  • ManufacturerAK Scientific
  • Product numberJ51544
  • Product descriptionCitilistat
  • Packaging5g
  • Price$25
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA117014
  • Product descriptionCetilistat 98+%
  • Packaging1g
  • Price$13
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA117014
  • Product descriptionCetilistat 98+%
  • Packaging5g
  • Price$23
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA117014
  • Product descriptionCetilistat 98+%
  • Packaging10g
  • Price$37
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA117014
  • Product descriptionCetilistat 98+%
  • Packaging25g
  • Price$69
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0002040
  • Product descriptionCITILISTAT 95.00%
  • Packaging1G
  • Price$178.5
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC7022
  • Product descriptionCetilistat
  • Packaging200mg
  • Price$45
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC7022
  • Product descriptionCetilistat
  • Packaging500mg
  • Price$65
  • Updated2021-12-16
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  • ManufacturerArctom
  • Product numberAS437583
  • Product descriptionCetilistat ≥98%
  • Packaging250mg
  • Price$5
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS437583
  • Product descriptionCetilistat ≥98%
  • Packaging1g
  • Price$13
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS437583
  • Product descriptionCetilistat ≥98%
  • Packaging5g
  • Price$23
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS437583
  • Product descriptionCetilistat ≥98%
  • Packaging10g
  • Price$37
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS437583
  • Product descriptionCetilistat ≥98%
  • Packaging25g
  • Price$68
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFH16224
  • Product descriptionCetilistat
  • Packaging10g
  • Price$45
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberBC166233
  • Product descriptionCetilistat
  • Packaging100mg
  • Price$50
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFH16224
  • Product descriptionCetilistat
  • Packaging25g
  • Price$70
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific J51544 Citilistat 5g $25 2021-12-16 Buy
Ambeed A117014 Cetilistat 98+% 1g $13 2021-12-16 Buy
Ambeed A117014 Cetilistat 98+% 5g $23 2021-12-16 Buy
Ambeed A117014 Cetilistat 98+% 10g $37 2021-12-16 Buy
Ambeed A117014 Cetilistat 98+% 25g $69 2021-12-16 Buy
American Custom Chemicals Corporation API0002040 CITILISTAT 95.00% 1G $178.5 2021-12-16 Buy
ApexBio Technology C7022 Cetilistat 200mg $45 2021-12-16 Buy
ApexBio Technology C7022 Cetilistat 500mg $65 2021-12-16 Buy
Arctom AS437583 Cetilistat ≥98% 250mg $5 2021-12-16 Buy
Arctom AS437583 Cetilistat ≥98% 1g $13 2021-12-16 Buy
Arctom AS437583 Cetilistat ≥98% 5g $23 2021-12-16 Buy
Arctom AS437583 Cetilistat ≥98% 10g $37 2021-12-16 Buy
Arctom AS437583 Cetilistat ≥98% 25g $68 2021-12-16 Buy
Biosynth Carbosynth FH16224 Cetilistat 10g $45 2021-12-16 Buy
Biosynth Carbosynth BC166233 Cetilistat 100mg $50 2021-12-16 Buy
Biosynth Carbosynth FH16224 Cetilistat 25g $70 2021-12-16 Buy

Properties

Melting point :72.0 to 76.0 °C
Boiling point :509.7±43.0 °C(Predicted)
Density :1.02
storage temp. :2-8°C
solubility :Chloroform (Slightly), Ethyl Acetate (Slightly)
form :Solid
pka :2.96±0.20(Predicted)
color :White to Off-White
InChI :InChI=1S/C25H39NO3/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-19-28-25-26-23-18-17-21(2)20-22(23)24(27)29-25/h17-18,20H,3-16,19H2,1-2H3
InChIKey :MVCQKIKWYUURMU-UHFFFAOYSA-N
SMILES :N1C2=CC=C(C)C=C2C(=O)OC=1OCCCCCCCCCCCCCCCC
CAS DataBase Reference :282526-98-1(CAS DataBase Reference)

Safety Information

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Description

Cetilistat (also known as ATL-962) was approved in September 2013 by the Japanese Ministry of Health, Labor and Welfare for the treatment of obesity, limited to patients with both type 2 diabetes mellitus (T2DM) and dyslipidemia, and with a body mass index (BMI)25 kg/m2 in spite of dietary treatment and/or exercise therapy. As with orlistat, cetilistat works via inhibition of pancreatic lipases in the gut to inhibit fat absorption and thereby reduce caloric uptake from diet. The medicinal chemistry program has not been described in the scientific literature, but the patent describing cetilistat also describes the synthesis of analogs with varied aryl substituents and lipophilic tails. The synthesis of cetilistat involves condensation of a hexadecylcarbonochloridate with 2-amino-5-methylbenzoic acid; other analogs were synthesized by varying the carbonochloridate and 2-aminobenzoic acid components. Cetilistat is a potent inhibitor of human and rat pancreatic lipase with IC50s of 15 and 136 nM, respectively, with little inhibition of trypsin or chymotrypsin.

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