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ChemicalBook >> CAS DataBase List >> Chlorzoxazone

Chlorzoxazone

Chlorzoxazone price.
  • $5 - $3507.4
  • Product name: Chlorzoxazone
  • CAS: 95-25-0
  • MF: C7H4ClNO2
  • MW: 169.57
  • EINECS:202-403-9
  • MDL Number:MFCD00005717
  • Synonyms:Biomioran;component of Parafon Forte;Escoflex;Miotran;Myoflexin;Myoflexine;Neoflex;parafonforte
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  • ManufacturerAHH
  • Product numberMT-06676
  • Product descriptionChlorzoxazone 97%
  • Packaging1000ml
  • Price$325
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberD608
  • Product descriptionChlorzoxazone
  • Packaging100g
  • Price$49
  • Updated2021-12-16
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  • ManufacturerAlfa Aesar
  • Product numberB24507
  • Product description5-Chloro-2(3H)-benzoxazolone, 99%
  • Packaging50g
  • Price$58.7
  • Updated2023-06-20
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberB24507
  • Product description5-Chloro-2(3H)-benzoxazolone, 99%
  • Packaging250g
  • Price$172
  • Updated2021-12-16
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  • ManufacturerAlfa Aesar
  • Product numberB24507
  • Product description5-Chloro-2(3H)-benzoxazolone, 99%
  • Packaging1000g
  • Price$468
  • Updated2021-12-16
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  • ManufacturerAlichem
  • Product number95250
  • Product description5-Chloro-2-hydroxybenzo[d]oxazole
  • Packaging10g
  • Price$3507.4
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA300568
  • Product description5-Chlorobenzo[d]oxazol-2(3H)-one 99+%
  • Packaging250mg
  • Price$5
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA300568
  • Product description5-Chlorobenzo[d]oxazol-2(3H)-one 99+%
  • Packaging5g
  • Price$6
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA300568
  • Product description5-Chlorobenzo[d]oxazol-2(3H)-one 99+%
  • Packaging10g
  • Price$8
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA300568
  • Product description5-Chlorobenzo[d]oxazol-2(3H)-one 99+%
  • Packaging25g
  • Price$13
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA300568
  • Product description5-Chlorobenzo[d]oxazol-2(3H)-one 99+%
  • Packaging100g
  • Price$34
  • Updated2021-12-16
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  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberCOR0003337
  • Product description2(3H)-BENZOXAZOLONE, 5-CHLORO- 95.00%
  • Packaging10MG
  • Price$402.66
  • Updated2021-12-16
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  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberCOR0003337
  • Product description2(3H)-BENZOXAZOLONE, 5-CHLORO- 95.00%
  • Packaging100MG
  • Price$426.6
  • Updated2021-12-16
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  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberCOR0003337
  • Product description2(3H)-BENZOXAZOLONE, 5-CHLORO- 95.00%
  • Packaging1G
  • Price$666
  • Updated2021-12-16
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  • ManufacturerArctom
  • Product numberAS512081
  • Product descriptionChlorzoxazone ≥99%
  • Packaging5g
  • Price$6
  • Updated2021-12-16
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  • ManufacturerArctom
  • Product numberAS512081
  • Product descriptionChlorzoxazone ≥99%
  • Packaging10g
  • Price$8
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AHH MT-06676 Chlorzoxazone 97% 1000ml $325 2021-12-16 Buy
AK Scientific D608 Chlorzoxazone 100g $49 2021-12-16 Buy
Alfa Aesar B24507 5-Chloro-2(3H)-benzoxazolone, 99% 50g $58.7 2023-06-20 Buy
Alfa Aesar B24507 5-Chloro-2(3H)-benzoxazolone, 99% 250g $172 2021-12-16 Buy
Alfa Aesar B24507 5-Chloro-2(3H)-benzoxazolone, 99% 1000g $468 2021-12-16 Buy
Alichem 95250 5-Chloro-2-hydroxybenzo[d]oxazole 10g $3507.4 2021-12-16 Buy
Ambeed A300568 5-Chlorobenzo[d]oxazol-2(3H)-one 99+% 250mg $5 2021-12-16 Buy
Ambeed A300568 5-Chlorobenzo[d]oxazol-2(3H)-one 99+% 5g $6 2021-12-16 Buy
Ambeed A300568 5-Chlorobenzo[d]oxazol-2(3H)-one 99+% 10g $8 2021-12-16 Buy
Ambeed A300568 5-Chlorobenzo[d]oxazol-2(3H)-one 99+% 25g $13 2021-12-16 Buy
Ambeed A300568 5-Chlorobenzo[d]oxazol-2(3H)-one 99+% 100g $34 2021-12-16 Buy
American Custom Chemicals Corporation COR0003337 2(3H)-BENZOXAZOLONE, 5-CHLORO- 95.00% 10MG $402.66 2021-12-16 Buy
American Custom Chemicals Corporation COR0003337 2(3H)-BENZOXAZOLONE, 5-CHLORO- 95.00% 100MG $426.6 2021-12-16 Buy
American Custom Chemicals Corporation COR0003337 2(3H)-BENZOXAZOLONE, 5-CHLORO- 95.00% 1G $666 2021-12-16 Buy
Arctom AS512081 Chlorzoxazone ≥99% 5g $6 2021-12-16 Buy
Arctom AS512081 Chlorzoxazone ≥99% 10g $8 2021-12-16 Buy

Properties

Melting point :191-192 °C (lit.)
Density :1.3771 (rough estimate)
refractive index :1.5557 (estimate)
storage temp. :room temp
solubility :DMSO: soluble50mg/mL, clear
pka :pKa 8.3 (Uncertain)
form :Powder
color :white to off-white
Water Solubility :0.1 g/100 mL
Merck :14,2194
LogP :1.816 (est)
CAS DataBase Reference :95-25-0(CAS DataBase Reference)
NIST Chemistry Reference :Chlorzoxazone(95-25-0)
EPA Substance Registry System :Chlorzoxazone (95-25-0)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Chlorzoxazone is a benzoxazolone derivative that causes skeletal muscle relaxation and blocks spasticity in clinical studies. Chlorzoxazone enhances small and intermediate conductance calcium-activated potassium channels (EC50s = 87 and 98 μM for KCa2.2 and KCa3.1, respectively). The cytochrome P450 isoform CYP2E1 converts chlorzoxazone to 6-hydroxy chlorzoxazone . The urinary excretion of this 6-hydroxy metabolite is often used as a probe of CYP2E1 activity in studies of hepatotoxicity.

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