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ChemicalBook >> CAS DataBase List >> Daminozide

Daminozide

Daminozide price.
  • $16.8 - $804.71
  • Product name: Daminozide
  • CAS: 1596-84-5
  • MF: C6H12N2O3
  • MW: 160.17
  • EINECS:216-485-9
  • MDL Number:MFCD00002787
  • Synonyms:4-(2,2-diMethylhydrazinyl)-4-oxobutanoic acid;DAMINOZIDE, 1GM, NEAT;DAMINOZID PESTANAL (SUCCINIC ACID MONO-(;SUCCINIC ACID 2,2-DIMETHYLHYDRAZIDE*PLAN T CELL CULT;Alar(B-9)Gr-(Daminozide)(SuccinicAcid2,2-DimethylHydrazide);Daminozide(B9);Alar(B-9)Gr;N-(DIMETHYLAMINO)SUCCINAMIC ACID
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  • AK Scientific
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  • 10mM(in1mLDMSO)
  • 10mM*1mLinDMSO(Solution)
  • 100g
  • 10mM(in 1mL DMSO)
  • 10mM*1mLinDMSO(Solid+Solvent)
  • ManufacturerAK Scientific
  • Product numberJ99573
  • Product description3-(N',N'-dimethylhydrazinecarbonyl)propanoicacid
  • Packaging100g
  • Price$80
  • Updated2021-12-16
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  • ManufacturerAK Scientific
  • Product numberS346
  • Product description3-(N',N'-dimethylhydrazinecarbonyl)propanoicacid
  • Packaging100g
  • Price$107
  • Updated2021-12-16
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  • ManufacturerAK Scientific
  • Product numberJ99573
  • Product description3-(N',N'-dimethylhydrazinecarbonyl)propanoicacid
  • Packaging1kg
  • Price$480
  • Updated2021-12-16
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  • ManufacturerApexBio Technology
  • Product numberA3348
  • Product descriptionDaminozide
  • Packaging50g
  • Price$99
  • Updated2021-12-16
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  • ManufacturerApexBio Technology
  • Product numberA3348
  • Product descriptionDaminozide
  • Packaging50g
  • Price$109
  • Updated2026-05-06
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  • ManufacturerApexBio Technology
  • Product numberA3348
  • Product descriptionDaminozide
  • Packaging25g
  • Price$72
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA3348
  • Product descriptionDaminozide
  • Packaging10mM(in1mLDMSO)
  • Price$77
  • Updated2026-05-06
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  • ManufacturerApexBio Technology
  • Product numberA3348
  • Product descriptionDaminozide
  • Packaging25g
  • Price$65
  • Updated2021-12-16
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  • ManufacturerApexBio Technology
  • Product numberA3348
  • Product descriptionDaminozide
  • Packaging10mM(in 1mL DMSO)
  • Price$50
  • Updated2021-12-16
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  • ManufacturerArctom
  • Product numberHY-13643
  • Product descriptionDaminozide 99.79%
  • Packaging10mM*1mLinDMSO(Solid+Solvent)
  • Price$50
  • Updated2026-05-26
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  • ManufacturerArctom
  • Product numberHY-13643R
  • Product descriptionDaminozide (Standard) 99.69%
  • Packaging50mg
  • Price$52
  • Updated2026-05-26
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  • ManufacturerArctom
  • Product numberHY-13643
  • Product descriptionDaminozide 99.79%
  • Packaging10mM*1mLinDMSO(Solution)
  • Price$53
  • Updated2026-05-26
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  • ManufacturerArctom
  • Product numberHY-13643
  • Product descriptionDaminozide 99.79%
  • Packaging1g
  • Price$57
  • Updated2026-05-26
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  • ManufacturerArctom
  • Product numberCS-1288
  • Product descriptionDaminozide ≥98.0%
  • Packaging500mg
  • Price$38
  • Updated2026-05-25
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  • ManufacturerArctom
  • Product numberCS-1288
  • Product descriptionDaminozide ≥98.0%
  • Packaging500mg
  • Price$38
  • Updated2026-05-26
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  • ManufacturerArctom
  • Product numberCS-1288
  • Product descriptionDaminozide ≥98.0%
  • Packaging1g
  • Price$45
  • Updated2026-05-25
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Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific J99573 3-(N',N'-dimethylhydrazinecarbonyl)propanoicacid 100g $80 2021-12-16 Buy
AK Scientific S346 3-(N',N'-dimethylhydrazinecarbonyl)propanoicacid 100g $107 2021-12-16 Buy
AK Scientific J99573 3-(N',N'-dimethylhydrazinecarbonyl)propanoicacid 1kg $480 2021-12-16 Buy
ApexBio Technology A3348 Daminozide 50g $99 2021-12-16 Buy
ApexBio Technology A3348 Daminozide 50g $109 2026-05-06 Buy
ApexBio Technology A3348 Daminozide 25g $72 2026-05-06 Buy
ApexBio Technology A3348 Daminozide 10mM(in1mLDMSO) $77 2026-05-06 Buy
ApexBio Technology A3348 Daminozide 25g $65 2021-12-16 Buy
ApexBio Technology A3348 Daminozide 10mM(in 1mL DMSO) $50 2021-12-16 Buy
Arctom HY-13643 Daminozide 99.79% 10mM*1mLinDMSO(Solid+Solvent) $50 2026-05-26 Buy
Arctom HY-13643R Daminozide (Standard) 99.69% 50mg $52 2026-05-26 Buy
Arctom HY-13643 Daminozide 99.79% 10mM*1mLinDMSO(Solution) $53 2026-05-26 Buy
Arctom HY-13643 Daminozide 99.79% 1g $57 2026-05-26 Buy
Arctom CS-1288 Daminozide ≥98.0% 500mg $38 2026-05-25 Buy
Arctom CS-1288 Daminozide ≥98.0% 500mg $38 2026-05-26 Buy
Arctom CS-1288 Daminozide ≥98.0% 1g $45 2026-05-25 Buy

Properties

Melting point :162-164 °C(lit.)
Boiling point :286.06°C (rough estimate)
Density :1.2751 (rough estimate)
refractive index :1.4500 (estimate)
storage temp. :Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility :Soluble in DMSO (up to 50 mg/ml), or in Water (up to 20 mg/ml with warming).
pka :5.59±0.10(Predicted)
form :White powder
color :White crystalline
Water Solubility :100 g/L
Merck :14,2810
BRN :1863230
Henry's Law Constant :2.3×104 mol/(m3Pa) at 25℃, Duchowicz et al. (2020)
Stability :Stable. Combustible. Incompatible with strong oxidizing agents, strong bases, strong acids, wetting agents, oils, copper-containing compounds.
Major Application :agriculture
cleaning products
cosmetics
environmental
food and beverages
personal care InChI :1S/C6H12N2O3/c1-8(2)7-5(9)3-4-6(10)11/h3-4H2,1-2H3,(H,7,9)(H,10,11)
InChIKey :NOQGZXFMHARMLW-UHFFFAOYSA-N
SMILES :CN(C)NC(=O)CCC(O)=O
CAS DataBase Reference :1596-84-5(CAS DataBase Reference)
NIST Chemistry Reference :Butanedioic acid, mono(2,2-dimethylhydrazide)(1596-84-5)
EPA Substance Registry System :Daminozide (1596-84-5)

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P337+P313 IF eye irritation persists: Get medical advice/attention.

Description

Daminozide is a highly selective inhibitor of the human 2-oxoglutarate (JmjC) histone demethylases KDM2A, PHF8, and KDM7A with IC50 values of 1.5, 0.55, and 2.1 μM, respectively. When tested for inhibition of other demethylase subfamily members (KDM3, KDM4, KDM5, KDM6) and other 2OG oxygenases (FIH, PHD2, BBOX1), daminozide was considerably less potent (IC50s > 100 μM). Daminozide is known to retard plant growth and was widely used in the 1960s for agricultural and horticultural applications to control plant size and fruit ripening before it was withdrawn because of carcinogenicity concerns.

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