Dexamethasone
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- $20 - $5210.5
- Product name: Dexamethasone
- CAS: 50-02-2
- MF: C22H29FO5
- MW: 392.47
- EINECS:200-003-9
- MDL Number:MFCD00064136
- Synonyms:DEXAMETHASONUM;DEXAMETHASONE;(11B,16A)-9-FLUORO-11,17,21-TRIHYDROXY-16-METHYL-PREGNA-1,4-DIENE-3,20-DIONE;1,4-PREGNADIEN-9ALPHA-FLUORO-16ALPHA-METHYL-11BETA, 17ALPHA, 21-TRIOL 3,20-DIONE;1,4-PREGNADIEN-9-ALPHA-FLUORO-16-ALPHA-METHYL-11-BETA, 17,21-TRIOL-3,20-DIONE;1,4-PREGNADIENE-3,20-DIONE-9ALPHA-FLUORO-16ALPHA METHYL-11BETA,17ALPHA,21-TRIOL;9ALPHA-FLUORO-16ALPHA-METHYL-11BETA,17ALPHA,21-TRIHYDROXY-1,4-PREGNADIENE-3,20-DIONE;9ALPHA-FLUORO-16ALPHA-METHYLPREDNISOLONE
160 prices
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Brand
- Adipogen Life Sciences
- AHH
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- Aronis compounds
- AvaChem
- Axon Medchem
- Biorbyt Ltd
- Biosynth
- Cayman Chemical
- Chemenu
- Chem-Impex
- ChemScene
- DC Chemicals
- Matrix Scientific
- Sigma-Aldrich
- TCI Chemical
- Thermo Scientific Chemicals
- Tocris
- TRC
- Usbiological
Package
- 10mM*1mLinDMSO
- 500μg
- 1mg
- 1mlx10mM(inDMSO)
- 2.5mg
- 5MG
- 10mg
- 100
- 20mg
- 25mg
- 50mg
- Y0001593
- Y0001177
- D0700000
- 10mM*1mLinDMSO(Solution)
- 100mg
- 125MG
- 250mg
- 500ul
- 500mg
- 1g
- 1000mg
- 1ml
- 5G
- 15 mg
- 20 mg
- 70 mg
- 10mM*1mLinDMSO(Solid+Solvent)
- 10g
- 0.1kg
- 10mM(in 1mL DMSO)
- 10mM(in1mLDMSO)
- 5000mg
- 0.01kg
- 25g
- 0.03kg
- 0.05kg
- 50g
- 100g
- 0.25kg
- ManufacturerAdipogen Life Sciences
- Product numberAG-CR1-3742-M050
- Product descriptionDexamethasone ≥98%(HPLC)
- Packaging50mg
- Price$20
- Updated2026-05-06
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberAG-CR1-3742-M500
- Product descriptionDexamethasone ≥98%(HPLC)
- Packaging500mg
- Price$35
- Updated2026-05-06
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberAG-CR1-3742-G001
- Product descriptionDexamethasone ≥98%(HPLC)
- Packaging1g
- Price$60
- Updated2026-05-06
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberAG-CR1-3742-G005
- Product descriptionDexamethasone ≥98%(HPLC)
- Packaging5G
- Price$210
- Updated2021-12-16
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberAG-CR1-3742-G005
- Product descriptionDexamethasone ≥98%(HPLC)
- Packaging5g
- Price$200
- Updated2026-05-06
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberCDX-D0359-G001
- Product descriptionDexamethasone ≥98%(HPLC)
- Packaging1g
- Price$213
- Updated2026-05-06
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberCDX-D0359-M500
- Product descriptionDexamethasone ≥98%(HPLC)
- Packaging500mg
- Price$156
- Updated2026-05-06
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberIAX-700-107-L001
- Product descriptionDexamethasone Sterile Solution ≥95%(HPLC)
- Packaging1ml
- Price$228
- Updated2026-05-06
- Buy
- ManufacturerAHH
- Product numberMT-07644
- Product descriptionDexamethasone 97%
- Packaging100g
- Price$366
- Updated2026-05-25
- Buy
- ManufacturerAHH
- Product numberMT-07644
- Product descriptionDexamethasone 97%
- Packaging100g
- Price$366
- Updated2026-05-26
- Buy
- ManufacturerAK Scientific
- Product numberF435
- Product descriptionDexamethasone
- Packaging25g
- Price$161
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberF435
- Product descriptionDexamethasone, meet USP specifications 97.0-103.0%
- Packaging1g
- Price$89
- Updated2026-06-04
- Buy
- ManufacturerAK Scientific
- Product numberJ10029
- Product descriptionDexamethasone 99%(HPLC)
- Packaging1g
- Price$85
- Updated2026-06-04
- Buy
- ManufacturerAK Scientific
- Product numberF435
- Product descriptionDexamethasone, meet USP specifications 97.0-103.0%
- Packaging100mg
- Price$45
- Updated2026-06-04
- Buy
- ManufacturerAK Scientific
- Product numberJ10029
- Product descriptionDexamethasone 99%(HPLC)
- Packaging100mg
- Price$39
- Updated2026-06-04
- Buy
- ManufacturerAK Scientific
- Product numberF435
- Product descriptionDexamethasone, meet USP specifications 97.0-103.0%
- Packaging5g
- Price$191
- Updated2026-06-04
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Adipogen Life Sciences | AG-CR1-3742-M050 | Dexamethasone ≥98%(HPLC) | 50mg | $20 | 2026-05-06 | Buy |
| Adipogen Life Sciences | AG-CR1-3742-M500 | Dexamethasone ≥98%(HPLC) | 500mg | $35 | 2026-05-06 | Buy |
| Adipogen Life Sciences | AG-CR1-3742-G001 | Dexamethasone ≥98%(HPLC) | 1g | $60 | 2026-05-06 | Buy |
| Adipogen Life Sciences | AG-CR1-3742-G005 | Dexamethasone ≥98%(HPLC) | 5G | $210 | 2021-12-16 | Buy |
| Adipogen Life Sciences | AG-CR1-3742-G005 | Dexamethasone ≥98%(HPLC) | 5g | $200 | 2026-05-06 | Buy |
| Adipogen Life Sciences | CDX-D0359-G001 | Dexamethasone ≥98%(HPLC) | 1g | $213 | 2026-05-06 | Buy |
| Adipogen Life Sciences | CDX-D0359-M500 | Dexamethasone ≥98%(HPLC) | 500mg | $156 | 2026-05-06 | Buy |
| Adipogen Life Sciences | IAX-700-107-L001 | Dexamethasone Sterile Solution ≥95%(HPLC) | 1ml | $228 | 2026-05-06 | Buy |
| AHH | MT-07644 | Dexamethasone 97% | 100g | $366 | 2026-05-25 | Buy |
| AHH | MT-07644 | Dexamethasone 97% | 100g | $366 | 2026-05-26 | Buy |
| AK Scientific | F435 | Dexamethasone | 25g | $161 | 2021-12-16 | Buy |
| AK Scientific | F435 | Dexamethasone, meet USP specifications 97.0-103.0% | 1g | $89 | 2026-06-04 | Buy |
| AK Scientific | J10029 | Dexamethasone 99%(HPLC) | 1g | $85 | 2026-06-04 | Buy |
| AK Scientific | F435 | Dexamethasone, meet USP specifications 97.0-103.0% | 100mg | $45 | 2026-06-04 | Buy |
| AK Scientific | J10029 | Dexamethasone 99%(HPLC) | 100mg | $39 | 2026-06-04 | Buy |
| AK Scientific | F435 | Dexamethasone, meet USP specifications 97.0-103.0% | 5g | $191 | 2026-06-04 | Buy |
Properties
Melting point :262-264 °C (lit.)
Boiling point :568.2±50.0 °C(Predicted)
alpha :75 º (c=1, dioxane)
Density :1.1283 (estimate)
refractive index :76 ° (C=1, Dioxane)
Flash point :9℃
storage temp. :2-8°C
solubility :ethanol: 1 mg/mL
form :powder
pka :12.13±0.70(Predicted)
color :off-white
biological source :synthetic (organic)
Water Solubility :10 mg/100 mL (25 ºC)
Sensitive :Light Sensitive
Merck :14,2943
BRN :2066651
Henry's Law Constant :1.4×102 mol/(m3Pa) at 25℃, HSDB (2015)
BCS Class :1 (CLogP), 3 (LogP)
Stability :Stable. Combustible. Incompatible with strong oxidizing agents, strong bases, acid anhydrides, acid chlorides. May be light sensitive.
InChIKey :UREBDLICKHMUKA-CXSFZGCWSA-N
SMILES :C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO
CAS DataBase Reference :50-02-2(CAS DataBase Reference)
NIST Chemistry Reference :Prednisolone, 9alpha-fluoro-16alpha-methyl-(50-02-2)
EPA Substance Registry System :Dexamethasone (50-02-2)
Boiling point :568.2±50.0 °C(Predicted)
alpha :75 º (c=1, dioxane)
Density :1.1283 (estimate)
refractive index :76 ° (C=1, Dioxane)
Flash point :9℃
storage temp. :2-8°C
solubility :ethanol: 1 mg/mL
form :powder
pka :12.13±0.70(Predicted)
color :off-white
biological source :synthetic (organic)
Water Solubility :10 mg/100 mL (25 ºC)
Sensitive :Light Sensitive
Merck :14,2943
BRN :2066651
Henry's Law Constant :1.4×102 mol/(m3Pa) at 25℃, HSDB (2015)
BCS Class :1 (CLogP), 3 (LogP)
Stability :Stable. Combustible. Incompatible with strong oxidizing agents, strong bases, acid anhydrides, acid chlorides. May be light sensitive.
InChIKey :UREBDLICKHMUKA-CXSFZGCWSA-N
SMILES :C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO
CAS DataBase Reference :50-02-2(CAS DataBase Reference)
NIST Chemistry Reference :Prednisolone, 9alpha-fluoro-16alpha-methyl-(50-02-2)
EPA Substance Registry System :Dexamethasone (50-02-2)
Safety Information
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| Signal word: | Danger | ||||||||||||
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Description
Dexamethasone is an Anti-inflammatory glucocorticoid that is used to treat inflammatory and autoimmune conditions such as rheumatoid arthritis and bronchospasm. It is useful to study apoptosis, cell signaling pathways and gene expression. It is associated with marbofloxacin and clotrimazole and finds application in veterinary medicine to treat difficult ear infections in dogs. It is also used to treat horses with swelling of of distal limbs and general bruising in combination with trichlormethiazide.Dexamethasone induces the production of phospholipase A2 inhibitory protein (lipocortin). It also inhibits induction of nitric oxide synthase (IC50=5 nM). Dexamethasone has been shown to cause reduction in cyclin A and Cd k2 activity, inhibition of G1/S transition in osteoblasts and inhibition of phosphorylation of Rb protein in vitro. Dexamethasone has been observed to induce apoptosis in human thymocytes and eosinophils, but inhibits apoptosis in neutrophils in vitro. Dexamethasone is an activator of IDO.
Dexamethasone Inhibits the expression of the inducible but not the constitutive nitric oxide synthase in vascular endothelial cells (IC50=5 nM). Dexamethasone regulates T cell survival, growth, and differentiation.Enhances active cation transport in aortic smooth muscle cells by stimulating the Na+-K+ pump. Has anti-inflammatory and anti-rheumatic properties. Induces apoptosis in human thymocytes. In general, 500-1000 nM of dexamethasone is sufficient to induce apoptosis following a 6-hour incubation at 37°C.
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