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ChemicalBook >> CAS DataBase List >> E-7820

E-7820

E-7820 price.
  • $37 - $1900
  • Product name: E-7820
  • CAS: 289483-69-8
  • MF: C17H12N4O2S
  • MW: 336.37
  • EINECS:
  • MDL Number:MFCD09833234
  • Synonyms:E-7820;ER 68203-00;3-cyano-N-(3-cyano-4-methyl-1H-indol-7-yl)benzenesulfonamide;N-(3-cyano-4-methyl-1H-indol-7-yl)-3-cyanobenzene-sulfonamide;E 7820; E-7820;CS-2701;ER68203-00;E7820;E-7820;E 7820;289483-69-8;Benzenesulfonamide, 3-cyano-N-(3-cyano-4-methyl-1H-indol-7-yl)-
Price19 Properties Safety Information Description
19 prices
Selected condition：
Brand
  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • Cayman Chemical
  • ChemScene
  • DC Chemicals
  • Tocris
Package
  • 10
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 1g
  • ManufacturerAK Scientific
  • Product number2475CB
  • Product descriptionN-(3-Cyano-4-methyl-1H-indol-7-yl)-3-cyanobenzene-sulfonamide
  • Packaging5mg
  • Price$139
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA950982
  • Product descriptionE-7820 98+%
  • Packaging1mg
  • Price$37
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA950982
  • Product descriptionE-7820 98+%
  • Packaging5mg
  • Price$74
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA950982
  • Product descriptionE-7820 98+%
  • Packaging10mg
  • Price$117
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA950982
  • Product descriptionE-7820 98+%
  • Packaging25mg
  • Price$171
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA950982
  • Product descriptionE-7820 98+%
  • Packaging50mg
  • Price$222
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA950982
  • Product descriptionE-7820 98+%
  • Packaging100mg
  • Price$288
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0005185
  • Product descriptionE-7820 95.00%
  • Packaging5MG
  • Price$502.29
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number25502
  • Product descriptionE7820 ≥98%
  • Packaging5mg
  • Price$37
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number25502
  • Product descriptionE7820 ≥98%
  • Packaging10mg
  • Price$68
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number25502
  • Product descriptionE7820 ≥98%
  • Packaging50mg
  • Price$283
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number25502
  • Product descriptionE7820 ≥98%
  • Packaging100mg
  • Price$530
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-6075
  • Product descriptionE7820 99.36%
  • Packaging5mg
  • Price$88
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-6075
  • Product descriptionE7820 99.36%
  • Packaging10mg
  • Price$140
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-6075
  • Product descriptionE7820 99.36%
  • Packaging25mg
  • Price$315
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-6075
  • Product descriptionE7820 99.36%
  • Packaging50mg
  • Price$450
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 2475CB N-(3-Cyano-4-methyl-1H-indol-7-yl)-3-cyanobenzene-sulfonamide 5mg $139 2021-12-16 Buy
Ambeed A950982 E-7820 98+% 1mg $37 2021-12-16 Buy
Ambeed A950982 E-7820 98+% 5mg $74 2021-12-16 Buy
Ambeed A950982 E-7820 98+% 10mg $117 2021-12-16 Buy
Ambeed A950982 E-7820 98+% 25mg $171 2021-12-16 Buy
Ambeed A950982 E-7820 98+% 50mg $222 2021-12-16 Buy
Ambeed A950982 E-7820 98+% 100mg $288 2021-12-16 Buy
American Custom Chemicals Corporation API0005185 E-7820 95.00% 5MG $502.29 2021-12-16 Buy
Cayman Chemical 25502 E7820 ≥98% 5mg $37 2024-03-01 Buy
Cayman Chemical 25502 E7820 ≥98% 10mg $68 2024-03-01 Buy
Cayman Chemical 25502 E7820 ≥98% 50mg $283 2024-03-01 Buy
Cayman Chemical 25502 E7820 ≥98% 100mg $530 2024-03-01 Buy
ChemScene CS-6075 E7820 99.36% 5mg $88 2021-12-16 Buy
ChemScene CS-6075 E7820 99.36% 10mg $140 2021-12-16 Buy
ChemScene CS-6075 E7820 99.36% 25mg $315 2021-12-16 Buy
ChemScene CS-6075 E7820 99.36% 50mg $450 2021-12-16 Buy
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Properties

Boiling point :626.2±65.0 °C(Predicted)
Density :1.48±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMSO:67.0(Max Conc. mg/mL);199.19(Max Conc. mM)
form :A crystalline solid
pka :8.17±0.30(Predicted)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

E7820 is a sulfonamide derivative and an angiogenesis inhibitor that inhibits bFGF- and VEGF-stimulated human umbilical vein endothelial cell (HUVEC) proliferation (IC50s = 0.1 and 0.081 μg/ml, respectively). It inhibits bFGF- and VEGF-stimulated tube formation of HUVECs in a concentration-dependent manner (IC50s = 0.2 and 0.24 μg/ml, respectively). E7820 selectively decreases the surface expression and mRNA levels of integrin α2 over CD31 and VE-cadherin in HUVECs. In vivo, E7820 (200 and 400 mg/kg) reduces tumor growth and inhibits angiogenesis in a WiDr colorectal cancer mouse xenograft model. It also reduces tumor weight in a panel of seven human colon, breast, pancreas, and kidney cancer mouse xenograft models, completely inhibits tumor growth in KP-1 pancreatic and LoVo colon cancer mouse xenograft models, and inhibits tumor growth in KP-1 and COLO 320DM mouse orthotopic transplantation models.

Suppliers and manufacturers

ATK CHEMICAL COMPANY LIMITED
Career Henan Chemica Co
InvivoChem
TargetMol Chemicals Inc.
Wuhan Topule Biopharmaceutical Co., Ltd
Aladdin Scientific
Amadis Chemical Company Limited Shanghai Dongyang Biotechnology Co., Ltd. Shanghai Boyle Chemical Co., Ltd. MedChemexpress LLC