EO 1428
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- $49 - $1385
- Product name: EO 1428
- CAS: 321351-00-2
- MF: C20H16BrClN2O
- MW: 415.71
- EINECS:
- MDL Number:MFCD11100188
- Synonyms:p38 MAP Kinase Inhibitor VIII;EO 1428;(2-Methylphenyl)-[4-[(2-amino-4-bromophenyl)amino]-2-chlorophenyl]methanone;p38 MAPK Inhibitor VIII;Methanone, [4-[(2-amino-4-bromophenyl)amino]-2-chlorophenyl](2-methylphenyl)-
21 prices
Selected condition:
Brand
- aablocks
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Cayman Chemical
- ChemScene
- Sigma-Aldrich
- Tocris
- TRC
- Usbiological
Package
- 50
- 10
- 1mg
- 2.5mg
- 5mg
- 10mg
- 50mg
- 5 mg
- Manufactureraablocks
- Product numberAA00CHKM
- Product descriptionp38 MAPK Inhibitor VIII ≥98%
- Packaging1mg
- Price$49
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00CHKM
- Product descriptionp38 MAPK Inhibitor VIII ≥98%
- Packaging5mg
- Price$130
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00CHKM
- Product descriptionp38 MAPK Inhibitor VIII ≥98%
- Packaging10mg
- Price$236
- Updated2026-05-28
- Buy
- ManufacturerAK Scientific
- Product number3107CR
- Product description(4-((2-Amino-4-bromophenyl)amino)-2-chlorophenyl)(2-methylphenyl)methanone
- Packaging1mg
- Price$147
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0001223
- Product descriptionEO 1428 95.00%
- Packaging5MG
- Price$500.02
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB7215
- Product descriptionEO 1428
- Packaging10mg
- Price$295
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberB7215
- Product descriptionEO 1428
- Packaging5mg
- Price$165
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberB7215
- Product descriptionEO 1428
- Packaging1mg
- Price$65
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberB7215
- Product descriptionEO 1428
- Packaging50mg
- Price$1385
- Updated2026-05-06
- Buy
- ManufacturerCayman Chemical
- Product number21229
- Product descriptionp38 MAPK Inhibitor VIII ≥98%
- Packaging10mg
- Price$236
- Updated2026-04-30
- Buy
- ManufacturerCayman Chemical
- Product number21229
- Product descriptionp38 MAPK Inhibitor VIII ≥98%
- Packaging1mg
- Price$49
- Updated2026-04-30
- Buy
- ManufacturerCayman Chemical
- Product number21229
- Product descriptionp38 MAPK Inhibitor VIII ≥98%
- Packaging5mg
- Price$130
- Updated2026-04-30
- Buy
- ManufacturerChemScene
- Product numberCS-0029384
- Product descriptionEO 1428 99.65%
- Packaging1mg
- Price$70
- Updated2026-06-04
- Buy
- ManufacturerChemScene
- Product numberCS-0029384
- Product descriptionEO 1428 99.65%
- Packaging5mg
- Price$174
- Updated2026-06-04
- Buy
- ManufacturerChemScene
- Product numberCS-0029384
- Product descriptionEO 1428 99.65%
- Packaging10mg
- Price$278
- Updated2026-06-04
- Buy
- ManufacturerSigma-Aldrich
- Product number506163
- Product descriptionp38 MAP Kinase Inhibitor VIII The p38 MAP Kinase Inhibitor VIII, also referenced under CAS 321351-00-2, controls the biological activity of p38 MAP Kinase. This small molecule/inhibitor is primarily used for Phosphorylation &
- Packaging5 mg
- Price$285
- Updated2026-04-30
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA00CHKM | p38 MAPK Inhibitor VIII ≥98% | 1mg | $49 | 2026-05-28 | Buy |
| aablocks | AA00CHKM | p38 MAPK Inhibitor VIII ≥98% | 5mg | $130 | 2026-05-28 | Buy |
| aablocks | AA00CHKM | p38 MAPK Inhibitor VIII ≥98% | 10mg | $236 | 2026-05-28 | Buy |
| AK Scientific | 3107CR | (4-((2-Amino-4-bromophenyl)amino)-2-chlorophenyl)(2-methylphenyl)methanone | 1mg | $147 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | INB0001223 | EO 1428 95.00% | 5MG | $500.02 | 2021-12-16 | Buy |
| ApexBio Technology | B7215 | EO 1428 | 10mg | $295 | 2026-05-06 | Buy |
| ApexBio Technology | B7215 | EO 1428 | 5mg | $165 | 2026-05-06 | Buy |
| ApexBio Technology | B7215 | EO 1428 | 1mg | $65 | 2026-05-06 | Buy |
| ApexBio Technology | B7215 | EO 1428 | 50mg | $1385 | 2026-05-06 | Buy |
| Cayman Chemical | 21229 | p38 MAPK Inhibitor VIII ≥98% | 10mg | $236 | 2026-04-30 | Buy |
| Cayman Chemical | 21229 | p38 MAPK Inhibitor VIII ≥98% | 1mg | $49 | 2026-04-30 | Buy |
| Cayman Chemical | 21229 | p38 MAPK Inhibitor VIII ≥98% | 5mg | $130 | 2026-04-30 | Buy |
| ChemScene | CS-0029384 | EO 1428 99.65% | 1mg | $70 | 2026-06-04 | Buy |
| ChemScene | CS-0029384 | EO 1428 99.65% | 5mg | $174 | 2026-06-04 | Buy |
| ChemScene | CS-0029384 | EO 1428 99.65% | 10mg | $278 | 2026-06-04 | Buy |
| Sigma-Aldrich | 506163 | p38 MAP Kinase Inhibitor VIII The p38 MAP Kinase Inhibitor VIII, also referenced under CAS 321351-00-2, controls the biological activity of p38 MAP Kinase. This small molecule/inhibitor is primarily used for Phosphorylation & | 5 mg | $285 | 2026-04-30 | Buy |
Properties
storage temp. :Store at +4°C
solubility :Soluble to 100 mM in DMSO and to 50 mM in ethanol
form :Powder
color :yellow
InChI :1S/C20H16BrClN2O/c1-12-4-2-3-5-15(12)20(25)16-8-7-14(11-17(16)22)24-19-9-6-13(21)10-18(19)23/h2-11,24H,23H2,1H3
InChIKey :HDCLCHNAEZNGNV-UHFFFAOYSA-N
SMILES :Brc1cc(c(cc1)Nc2cc(c(cc2)C(=O)c3c(cccc3)C)Cl)N
solubility :Soluble to 100 mM in DMSO and to 50 mM in ethanol
form :Powder
color :yellow
InChI :1S/C20H16BrClN2O/c1-12-4-2-3-5-15(12)20(25)16-8-7-14(11-17(16)22)24-19-9-6-13(21)10-18(19)23/h2-11,24H,23H2,1H3
InChIKey :HDCLCHNAEZNGNV-UHFFFAOYSA-N
SMILES :Brc1cc(c(cc1)Nc2cc(c(cc2)C(=O)c3c(cccc3)C)Cl)N
Safety Information
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Description
p38 MAP Kinase Inhibitor VIII is a synthetic 4-aminobenzophenone small molecule identified in an optimization study for inhibitors of p38 MAP kinase. p38 MAP Kinase Inhibitor VIII is described to inhibit the p38α and p38β isoforms of the kinase by occupying the ATP-binding cleft. This inhibition is described to potently block the release of TNF-α (IC50 = 5 nM) and the proinflammatory interleukins IL-1β, IL-6, IL-8, and IL-10 (IC50s = 30, 17, 4, 74 nM).More related product prices
1638-41-1 p38 MAP Kinase Inhibitor III 2-(4-CHLOROPHENYL)-4-(4-FLUOROPHENYL)-5-PYRIDIN-4-YL-1,2-DIHYDROPYRAZOL-3-ONERelated product price
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