ChemicalBook >> CAS DataBase List >>EO 1428
EO 1428
- CAS No.
- 321351-00-2
- Chemical Name:
- EO 1428
- Synonyms
- EO 1428;p38 MAPK Inhibitor VIII;p38 MAP Kinase Inhibitor VIII;(2-Methylphenyl)-[4-[(2-amino-4-bromophenyl)amino]-2-chlorophenyl]methanone;Methanone, [4-[(2-amino-4-bromophenyl)amino]-2-chlorophenyl](2-methylphenyl)-
- CBNumber:
- CB12455755
- Molecular Formula:
- C20H16BrClN2O
- Molecular Weight:
- 415.71
- MDL Number:
- MFCD11100188
- MOL File:
- 321351-00-2.mol
Last updated:2023-06-30 15:45:59
| storage temp. | Store at +4°C |
|---|---|
| solubility | Soluble to 100 mM in DMSO and to 50 mM in ethanol |
| form | Powder |
| FDA UNII | MV2RHJ680O |
EO 1428 price More Price(11)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 21229 | p38 MAPK Inhibitor VIII ≥98% | 321351-00-2 | 1mg | $44 | 2024-03-01 | Buy |
| Cayman Chemical | 21229 | p38 MAPK Inhibitor VIII ≥98% | 321351-00-2 | 5mg | $118 | 2024-03-01 | Buy |
| Cayman Chemical | 21229 | p38 MAPK Inhibitor VIII ≥98% | 321351-00-2 | 10mg | $214 | 2024-03-01 | Buy |
| Tocris | 2908 | EO1428 ≥98%(HPLC) | 321351-00-2 | 10 | $225 | 2021-12-16 | Buy |
| Tocris | 2908 | EO1428 ≥98%(HPLC) | 321351-00-2 | 50 | $915 | 2021-12-16 | Buy |
EO 1428 Chemical Properties,Uses,Production
Uses
EO 1428 is a p38 MAP kinase inhibitor with high antiinflammatory activity.
Definition
ChEBI: [4-(2-amino-4-bromoanilino)-2-chlorophenyl]-(2-methylphenyl)methanone is a member of benzophenones.
Biological Activity
Selective inhibitor of p38 α and p38 β 2 that displays no activity at p38 γ , p38 δ , ERK1/2 and JNK1. Inhibits production of inflammatory cytokines including IL-8, TNF- α , IL-6, IL-1 β and IL-10 (IC 50 values are 4, 5, 17, 30 and 74 nM respectively). Displays anti-inflammatory activity in murine models of acute and chronic dermatitis.
storage
Store at +4°C
EO 1428 Preparation Products And Raw materials
Raw materials
Preparation Products
EO 1428 Suppliers
Global( 26)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | sales@molcore.com | China | 49739 | 58 |
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 52927 | 58 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 821-50328103-801 18930552037 | 3bsc@sina.com | China | 15848 | 69 |
| EMMX Biotechnology LLC | 888-539-0666 | info@emmx.com | United States | 8449 | 60 |
| MQ (shanghai) Pharmaceuticals Co., Ltd. | 13761635123 | 1014988033@qq.com | China | 4979 | 55 |
| MedBioPharmaceutical Technology Inc | 021-69568360 18916172912 | order@med-bio.cn | China | 8141 | 58 |
| TargetMol Chemicals Inc. | 4008200310 | marketing@tsbiochem.com | China | 24131 | 58 |
| Nantong QuanYi Biotechnology Co., Ltd | 0513-66337626 18051384581 | sales@chemhifuture.com | China | 4030 | 58 |
| Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | customer_service@efebio.com | China | 8740 | 58 |
321351-00-2(EO 1428)Related Search:
p38 MAP Kinase Inhibitor VIII
EO 1428
(2-Methylphenyl)-[4-[(2-amino-4-bromophenyl)amino]-2-chlorophenyl]methanone
p38 MAPK Inhibitor VIII
Methanone, [4-[(2-amino-4-bromophenyl)amino]-2-chlorophenyl](2-methylphenyl)-
321351-00-2
C20H16BrClN2O