EPTAPIRONE
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- $41 - $3600
- Product name: EPTAPIRONE
- CAS: 179756-58-2
- MF: C16H23N7O2
- MW: 345.4
- EINECS:
- MDL Number:MFCD08690608
- Synonyms:EPTAPIRONE;4-methyl-2-(4-(4-(pyrimidin-2-yl)piperazin-1-yl)butyl)-1,2,4-triazine-3,5(2H,4H)-dione;F 11440;4-Methyl-2-[4-[4-(2-pyrimidinyl)-1-piperazinyl]butyl]-1,2,4-triazine-3,5(2H,4H)-dione;F-11440;F11440;1,2,4-Triazine-3,5(2H,4H)-dione, 4-methyl-2-[4-[4-(2-pyrimidinyl)-1-piperazinyl]butyl]-;Eptapirone(F11440);Serotonin Receptor,5-HT Receptor,Eptapirone,inhibit,F-11440,5-hydroxytryptamine Receptor,Inhibitor,F11440
46 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- Ambeed
- American Custom Chemicals Corporation
- Arctom
- Biorbyt Ltd
- Biosynth
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- DC Chemicals
- TRC
Package
- 1mg
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 200mg
- 250MG
- 10mM*1mLinDMSO
- 1g
- 1mlx10mM(inDMSO)
- Manufactureraablocks
- Product numberAA00275L
- Product descriptionF 11440
- Packaging10mg
- Price$56
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00275L
- Product descriptionF 11440
- Packaging50mg
- Price$139
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00275L
- Product descriptionF 11440
- Packaging100mg
- Price$197
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00275L
- Product descriptionF 11440
- Packaging25mg
- Price$87
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberX210426
- Product description4-methyl-2-(4-(4-(pyrimidin-2-yl)piperazin-1-yl)butyl)-1,2,4-triazine-3,5(2H,4H)-dione 95%
- Packaging100MG
- Price$205
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberX210426
- Product description4-methyl-2-(4-(4-(pyrimidin-2-yl)piperazin-1-yl)butyl)-1,2,4-triazine-3,5(2H,4H)-dione 95%
- Packaging250MG
- Price$410
- Updated2026-05-27
- Buy
- ManufacturerAmbeed
- Product numberA113567
- Product descriptionF11440 98+%
- Packaging1g
- Price$3600
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA113567
- Product descriptionF11440 98+%
- Packaging5mg
- Price$68
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA113567
- Product descriptionF11440 98+%
- Packaging10mg
- Price$114
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA113567
- Product descriptionF11440 98+%
- Packaging25mg
- Price$193
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA113567
- Product descriptionF11440 98+%
- Packaging50mg
- Price$251
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0002409
- Product descriptionEPTAPIRONE 95.00%
- Packaging5MG
- Price$499.81
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS436283
- Product descriptionF11440 ≥98%
- Packaging25mg
- Price$191
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb1304455
- Product descriptionEptapirone 99.89%(Mayvarybetweenbatches)
- Packaging1mlx10mM(inDMSO)
- Price$70
- Updated2026-05-06
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb1225895
- Product descriptionF-11440 >98%(HPLC)
- Packaging5mg
- Price$140
- Updated2026-05-06
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb1225895
- Product descriptionF-11440 >98%(HPLC)
- Packaging10mg
- Price$220
- Updated2026-05-06
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA00275L | F 11440 | 10mg | $56 | 2026-05-28 | Buy |
| aablocks | AA00275L | F 11440 | 50mg | $139 | 2026-05-28 | Buy |
| aablocks | AA00275L | F 11440 | 100mg | $197 | 2026-05-28 | Buy |
| aablocks | AA00275L | F 11440 | 25mg | $87 | 2026-05-28 | Buy |
| ACHEMBLOCK | X210426 | 4-methyl-2-(4-(4-(pyrimidin-2-yl)piperazin-1-yl)butyl)-1,2,4-triazine-3,5(2H,4H)-dione 95% | 100MG | $205 | 2026-05-27 | Buy |
| ACHEMBLOCK | X210426 | 4-methyl-2-(4-(4-(pyrimidin-2-yl)piperazin-1-yl)butyl)-1,2,4-triazine-3,5(2H,4H)-dione 95% | 250MG | $410 | 2026-05-27 | Buy |
| Ambeed | A113567 | F11440 98+% | 1g | $3600 | 2021-12-16 | Buy |
| Ambeed | A113567 | F11440 98+% | 5mg | $68 | 2021-12-16 | Buy |
| Ambeed | A113567 | F11440 98+% | 10mg | $114 | 2021-12-16 | Buy |
| Ambeed | A113567 | F11440 98+% | 25mg | $193 | 2021-12-16 | Buy |
| Ambeed | A113567 | F11440 98+% | 50mg | $251 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | INB0002409 | EPTAPIRONE 95.00% | 5MG | $499.81 | 2021-12-16 | Buy |
| Arctom | AS436283 | F11440 ≥98% | 25mg | $191 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb1304455 | Eptapirone 99.89%(Mayvarybetweenbatches) | 1mlx10mM(inDMSO) | $70 | 2026-05-06 | Buy |
| Biorbyt Ltd | orb1225895 | F-11440 >98%(HPLC) | 5mg | $140 | 2026-05-06 | Buy |
| Biorbyt Ltd | orb1225895 | F-11440 >98%(HPLC) | 10mg | $220 | 2026-05-06 | Buy |
Properties
Boiling point :517.4±60.0 °C(Predicted)
Density :1.35±0.1 g/cm3(Predicted)
storage temp. :Inert atmosphere,Room Temperature
solubility :DMF:10.0(Max Conc. mg/mL);28.95(Max Conc. mM)
form :A crystalline solid
pka :7.72±0.10(Predicted)
color :White to off-white
Density :1.35±0.1 g/cm3(Predicted)
storage temp. :Inert atmosphere,Room Temperature
solubility :DMF:10.0(Max Conc. mg/mL);28.95(Max Conc. mM)
form :A crystalline solid
pka :7.72±0.10(Predicted)
color :White to off-white
Safety Information
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| Signal word: | Warning | |||||||||||||||||||||||||||||||||||
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Description
Eptapirone is a potent agonist of the serotonin (5-HT) receptor subtype 5-HT1A (Ki = 4.8 nM in a radioligand binding assay). It is selective for 5-HT1A over other 5-HT receptor subtypes, dopamine D2 receptors, α1-adrenergic receptors, and histamine H1 receptors (Kis = <10,000, 1,770, 691.8, and <10,000 nM, respectively). Eptapirone inhibits cAMP stimulation induced by forskolin in HA7 cells transfected with human 5-HT1A receptors (EC50 = 158 nM). In vivo, eptapirone increases extracellular 5-HT in the ventral hippocampus of rats (ED50 = 0.049 mg/kg) and serum corticosterone levels when administered p.o. or i.p. (ED50s = 0.16 and 0.057 mg/kg, respectively). It decreases immobility in rats in a forced swim test and increases punished responding in a pigeon conflict procedure, demonstrating antidepressant-like and anxiolytic activity. Eptapirone (2.5 mg/kg, p.o.) also attenuates hypertension and tachycardia induced by sibutramine in rats with no effect on sibutramine-induced hypophagia.More related product prices
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