Efavirenz
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- $25 - $2400
- Product name: Efavirenz
- CAS: 154598-52-4
- MF: C14H9ClF3NO2
- MW: 315.67
- EINECS:620-492-6
- MDL Number:MFCD05662344
- Synonyms:(S)-6-Chloro-4-(cyclopropylethynyl)-1，4-dihydro-4-(trifluoromethyl) 2H-3，1-benzoxazin-2-one;(4S)-6-chloro-4-(2-cyclopropylethynyl)-4-(trifluoromethyl)-1H-3,1-benzoxazin-2-one;Efavirenz (200 mg);(4S)-6-chloro-4-(2-cyclopropylethynyl)-4-(trifluoroMethyl)-2,4-dihydro-1H-3,1-benzoxazin-2-one;2H-3,1-Benzoxazin-2-one, 6-chloro-4-(2-cyclopropylethynyl)-1,4-dihydro-4-(trifluoroMethyl)-, (4S)-;efavuirenz;Efavirenz solution;(S)-6-CHLORO-4-(CYCLOPROPYLETHYNYL)-4-(TRIFLUOROMETHYL)-1H-BENZO[D][1,3]OXAZIN-2(4H)-ONE
78 prices
Selected condition：
Brand
- ACHEMBLOCK
- Adipogen Life Sciences
- AHH
- AK Scientific
- ApexBio Technology
- Arctom
- Axon Medchem
- Biorbyt Ltd
- Biosynth
- Cayman Chemical
- Chem-Impex
- ChemScene
- Chemtos
- Crysdot
- CSNpharm
- DC Chemicals
- Medical Isotopes, Inc.
- Sigma-Aldrich
- TCI Chemical
- TRC
- Usbiological
Package
- 10mM(1mLinDMSO)
- 20mg
- 25mg
- 100mg
- 200mg
- 500mg
- 2g
- 5G
- 100G
- 250G
- 5mg
- 10mg
- 50mg
- 0.1g
- 250mg
- 1ml
- 25G
- 1g
- 10mM(in 1mL DMSO)
- 10mM(in1mLDMSO)
- ManufacturerACHEMBLOCK
- Product numberX191305
- Product description(S)-6-Chloro-4-(2-cyclopropylethynyl)-4-(trifluoromethyl)-2,4-dihydro-1H-3,1-benzoxazin-2-one 95.00%
- Packaging5G
- Price$170
- Updated2026-05-25
- Buy
- ManufacturerACHEMBLOCK
- Product numberX191305
- Product description(S)-6-Chloro-4-(2-cyclopropylethynyl)-4-(trifluoromethyl)-2,4-dihydro-1H-3,1-benzoxazin-2-one 95.00%
- Packaging5G
- Price$170
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberX191305
- Product description(S)-6-Chloro-4-(2-cyclopropylethynyl)-4-(trifluoromethyl)-2,4-dihydro-1H-3,1-benzoxazin-2-one 95.00%
- Packaging25G
- Price$660
- Updated2026-05-25
- Buy
- ManufacturerACHEMBLOCK
- Product numberX191305
- Product description(S)-6-Chloro-4-(2-cyclopropylethynyl)-4-(trifluoromethyl)-2,4-dihydro-1H-3,1-benzoxazin-2-one 95.00%
- Packaging25G
- Price$660
- Updated2026-05-27
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberAG-CR1-3751-M250
- Product descriptionEfavirenz ≥98%(HPLC)
- Packaging250mg
- Price$250
- Updated2026-05-06
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberAG-CR1-3751-M050
- Product descriptionEfavirenz ≥98%(HPLC)
- Packaging50mg
- Price$90
- Updated2026-05-06
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberAG-CR1-3751-M050
- Product descriptionEfavirenz ≥98%(HPLC)
- Packaging50mg
- Price$110
- Updated2021-12-16
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberAG-CR1-3751-M010
- Product descriptionEfavirenz ≥98%(HPLC)
- Packaging10mg
- Price$40
- Updated2026-05-06
- Buy
- ManufacturerAHH
- Product numberAPI-1192
- Product descriptionEfavirenz 98%
- Packaging0.1g
- Price$630
- Updated2021-12-16
- Buy
- ManufacturerAHH
- Product numberAPI-1192
- Product descriptionEfavirenz 97%
- Packaging0.1g
- Price$630
- Updated2026-05-25
- Buy
- ManufacturerAHH
- Product numberAPI-1192
- Product descriptionEfavirenz 97%
- Packaging0.1g
- Price$630
- Updated2026-05-26
- Buy
- ManufacturerAK Scientific
- Product numberJ95133
- Product descriptionEfavirenz
- Packaging1g
- Price$25
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB1119
- Product descriptionEfavirenz
- Packaging5mg
- Price$50
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberB1119
- Product descriptionEfavirenz
- Packaging10mM(in 1mL DMSO)
- Price$55
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB1119
- Product descriptionEfavirenz
- Packaging10mM(in1mLDMSO)
- Price$61
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberB1119
- Product descriptionEfavirenz
- Packaging10mg
- Price$76
- Updated2026-05-06
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| ACHEMBLOCK | X191305 | (S)-6-Chloro-4-(2-cyclopropylethynyl)-4-(trifluoromethyl)-2,4-dihydro-1H-3,1-benzoxazin-2-one 95.00% | 5G | $170 | 2026-05-25 | Buy |
| ACHEMBLOCK | X191305 | (S)-6-Chloro-4-(2-cyclopropylethynyl)-4-(trifluoromethyl)-2,4-dihydro-1H-3,1-benzoxazin-2-one 95.00% | 5G | $170 | 2026-05-27 | Buy |
| ACHEMBLOCK | X191305 | (S)-6-Chloro-4-(2-cyclopropylethynyl)-4-(trifluoromethyl)-2,4-dihydro-1H-3,1-benzoxazin-2-one 95.00% | 25G | $660 | 2026-05-25 | Buy |
| ACHEMBLOCK | X191305 | (S)-6-Chloro-4-(2-cyclopropylethynyl)-4-(trifluoromethyl)-2,4-dihydro-1H-3,1-benzoxazin-2-one 95.00% | 25G | $660 | 2026-05-27 | Buy |
| Adipogen Life Sciences | AG-CR1-3751-M250 | Efavirenz ≥98%(HPLC) | 250mg | $250 | 2026-05-06 | Buy |
| Adipogen Life Sciences | AG-CR1-3751-M050 | Efavirenz ≥98%(HPLC) | 50mg | $90 | 2026-05-06 | Buy |
| Adipogen Life Sciences | AG-CR1-3751-M050 | Efavirenz ≥98%(HPLC) | 50mg | $110 | 2021-12-16 | Buy |
| Adipogen Life Sciences | AG-CR1-3751-M010 | Efavirenz ≥98%(HPLC) | 10mg | $40 | 2026-05-06 | Buy |
| AHH | API-1192 | Efavirenz 98% | 0.1g | $630 | 2021-12-16 | Buy |
| AHH | API-1192 | Efavirenz 97% | 0.1g | $630 | 2026-05-25 | Buy |
| AHH | API-1192 | Efavirenz 97% | 0.1g | $630 | 2026-05-26 | Buy |
| AK Scientific | J95133 | Efavirenz | 1g | $25 | 2021-12-16 | Buy |
| ApexBio Technology | B1119 | Efavirenz | 5mg | $50 | 2026-05-06 | Buy |
| ApexBio Technology | B1119 | Efavirenz | 10mM(in 1mL DMSO) | $55 | 2021-12-16 | Buy |
| ApexBio Technology | B1119 | Efavirenz | 10mM(in1mLDMSO) | $61 | 2026-05-06 | Buy |
| ApexBio Technology | B1119 | Efavirenz | 10mg | $76 | 2026-05-06 | Buy |
Properties
Melting point :139-141°C
alpha :D20 -84.7° (c = 0.005 g/ml in CH3Cl); D25 -94.1° (c = 0.300 in methanol)
Boiling point :340.6±42.0 °C(Predicted)
Density :1.53±0.1 g/cm3(Predicted)
Flash point :2℃
storage temp. :-20°C
solubility :DMSO: soluble15mg/mL, clear
pka :10.2(at 25℃)
form :powder or crystals
color :white to beige
optical activity :[α]/D -90 to -100°, c = 1 in methanol
Water Solubility :8mg/L(temperature not stated)
λmax :247nm(MeOH)(lit.)
Merck :14,3521
Henry's Law Constant :1.4×103 mol/(m3Pa) at 25℃, HSDB (2015)
BCS Class :4
InChI :1S/C14H9ClF3NO2/c15-9-3-4-11-10(7-9)13(14(16,17)18,21-12(20)19-11)6-5-8-1-2-8/h3-4,7-8H,1-2H2,(H,19,20)/t13-/m0/s1
InChIKey :XPOQHMRABVBWPR-ZDUSSCGKSA-N
SMILES :ClC1=CC=C2C([C@@](C#CC3CC3)(C(F)(F)F)OC(N2)=O)=C1
EPA Substance Registry System :2H-3,1-Benzoxazin-2-one, 6-chloro-4-(2-cyclopropylethynyl)-1,4-dihydro-4-(trifluoromethyl)-, (4S)- (154598-52-4)
alpha :D20 -84.7° (c = 0.005 g/ml in CH3Cl); D25 -94.1° (c = 0.300 in methanol)
Boiling point :340.6±42.0 °C(Predicted)
Density :1.53±0.1 g/cm3(Predicted)
Flash point :2℃
storage temp. :-20°C
solubility :DMSO: soluble15mg/mL, clear
pka :10.2(at 25℃)
form :powder or crystals
color :white to beige
optical activity :[α]/D -90 to -100°, c = 1 in methanol
Water Solubility :8mg/L(temperature not stated)
λmax :247nm(MeOH)(lit.)
Merck :14,3521
Henry's Law Constant :1.4×103 mol/(m3Pa) at 25℃, HSDB (2015)
BCS Class :4
InChI :1S/C14H9ClF3NO2/c15-9-3-4-11-10(7-9)13(14(16,17)18,21-12(20)19-11)6-5-8-1-2-8/h3-4,7-8H,1-2H2,(H,19,20)/t13-/m0/s1
InChIKey :XPOQHMRABVBWPR-ZDUSSCGKSA-N
SMILES :ClC1=CC=C2C([C@@](C#CC3CC3)(C(F)(F)F)OC(N2)=O)=C1
EPA Substance Registry System :2H-3,1-Benzoxazin-2-one, 6-chloro-4-(2-cyclopropylethynyl)-1,4-dihydro-4-(trifluoromethyl)-, (4S)- (154598-52-4)
Safety Information
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Description
Non-nucleoside reverse transcriptase inhibitors (NNRTIs) are highly specific and potent allosteric inhibitors of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase. Efavirenz is an NNRTI that prevents RNA plus-strand initiation with an IC50 value of 17 nM. Efavirenz also inhibits the late stages of HIV-1 replication by interfering with HIV-1 Gag-Pol polyprotein processing. It has been used in combination therapy with drugs directed at the treatment of opportunistic infections such as HIV and cancer.More related product prices
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$9-1433.6 - Poly(vinyl alcohol)
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$10-1070
Suppliers and manufacturers
Henan Tianfu Chemical Co.,Ltd.
Shaanxi Yikanglong Biotechnology Co., Ltd.
Biochempartner
Shenzhen Nexconn Pharmatechs Ltd
Shanghai Longyu Biotechnology Co., Ltd.
