Epothilone B

Melting point :95-97°C
alpha :D21 -35° (c = 0.7 in methanol)
Boiling point :680.2±55.0 °C(Predicted)
Density :1.136
storage temp. :Store at -20°C
solubility :Soluble in DMSO (up to 40 mg/ml) or in Ethanol (up to 35 mg/ml).
form :White to off-white solid
pka :13.57±0.70(Predicted)
color :colorless
optical activity :-35.021 (methanol)
biological source :Sorangium cellulosum
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month.
InChIKey :QXRSDHAAWVKZLJ-PVYNADRNSA-N
SMILES :[C@]12([H])[C@](C)(O1)CCC[C@H](C)[C@H](O)[C@@H](C)C(=O)C(C)(C)[C@@H](O)CC(=O)O[C@H](/C(/C)=C/C1=CSC(C)=N1)C2
CAS DataBase Reference :152044-54-7

Symbol(GHS):
Signal word:	Danger
Hazard statements:	Code Hazard statements Hazard class Category Signal word Pictogram P-Codes H300 Fatal if swallowed Acute toxicity,oral Category 1, 2 Danger P264, P270, P301+P310, P321, P330,P405, P501 H310 Fatal in contact with skin Acute toxicity,dermal Category 1, 2 Danger P262, P264, P270, P280, P302+P350,P310, P322, P361, P363, P405, P501 H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362 H317 May cause an allergic skin reaction Sensitisation, Skin Category 1 Warning P261, P272, P280, P302+P352,P333+P313, P321, P363, P501 H341 Suspected of causing genetic defects Germ cell mutagenicity Category 2 Warning P201,P202, P281, P308+P313, P405,P501 H360 May damage fertility or the unborn child Reproductive toxicity Category 1A, 1B Danger H372 Causes damage to organs through prolonged or repeated exposure Specific target organ toxicity, repeated exposure Category 1 Danger P260, P264, P270, P314, P501 H410 Very toxic to aquatic life with long lasting effects Hazardous to the aquatic environment, long-term hazard Category 1 Warning P273, P391, P501
Precautionary statements:	P201 Obtain special instructions before use. P202 Do not handle until all safety precautions have been read and understood. P260 Do not breathe dust/fume/gas/mist/vapours/spray. P261 Avoid breathing dust/fume/gas/mist/vapours/spray. P262 Do not get in eyes, on skin, or on clothing. P264 Wash hands thoroughly after handling. P264 Wash skin thouroughly after handling. P270 Do not eat, drink or smoke when using this product. P272 Contaminated work clothing should not be allowed out of the workplace. P273 Avoid release to the environment. P280 Wear protective gloves/protective clothing/eye protection/face protection. P281 Use personal protective equipment as required. P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. P302+P350 IF ON SKIN: Gently wash with plenty of soap and water. P302+P352 IF ON SKIN: wash with plenty of soap and water. P308+P313 IF exposed or concerned: Get medical advice/attention. P310 Immediately call a POISON CENTER or doctor/physician. P314 Get medical advice/attention if you feel unwell. P321 Specific treatment (see … on this label). P322 Specific measures (see …on this label). P330 Rinse mouth. P332+P313 IF SKIN irritation occurs: Get medical advice/attention. P333+P313 IF SKIN irritation or rash occurs: Get medical advice/attention. P361 Remove/Take off immediately all contaminated clothing. P362 Take off contaminated clothing and wash before reuse. P363 Wash contaminated clothing before reuse. P391 Collect spillage. Hazardous to the aquatic environment P405 Store locked up. P501 Dispose of contents/container to..…