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ChemicalBook >> CAS DataBase List >> Erlotinib

Erlotinib

Erlotinib price.
  • $25 - $350
  • Product name: Erlotinib
  • CAS: 183321-74-6
  • MF: C22H23N3O4
  • MW: 393.44
  • EINECS:689-196-2
  • MDL Number:MFCD07781272
  • Synonyms:ERLOTINIB;ERLOTINIB HCL;ERLOTINIB HCL SALT;4-[(3-ethynylphenyl)amino]-6,7-bis(2-methoxyethoxy)quinazoline;n-(3-ethynylphenyl)[6,7-bis(2-methoxyethoxy)quinazolin-4-yl]amine;Erlotinib Hydrochloirde;OSI 744;R 1415
4 prices
Selected condition:

Brand

  • Cayman Chemical

Package

  • 250mg
  • 500mg
  • 1g
  • 5g
  • ManufacturerCayman Chemical
  • Product number10483
  • Product descriptionErlotinib ≥98%
  • Packaging250mg
  • Price$25
  • Updated2018-11-13
  • Buy
  • ManufacturerCayman Chemical
  • Product number10483
  • Product descriptionErlotinib ≥98%
  • Packaging500mg
  • Price$45
  • Updated2018-11-13
  • Buy
  • ManufacturerCayman Chemical
  • Product number10483
  • Product descriptionErlotinib ≥98%
  • Packaging1g
  • Price$80
  • Updated2018-11-13
  • Buy
  • ManufacturerCayman Chemical
  • Product number10483
  • Product descriptionErlotinib ≥98%
  • Packaging5g
  • Price$350
  • Updated2018-11-13
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Cayman Chemical 10483 Erlotinib ≥98% 250mg $25 2018-11-13 Buy
Cayman Chemical 10483 Erlotinib ≥98% 500mg $45 2018-11-13 Buy
Cayman Chemical 10483 Erlotinib ≥98% 1g $80 2018-11-13 Buy
Cayman Chemical 10483 Erlotinib ≥98% 5g $350 2018-11-13 Buy

Properties

Density  :1.24
CAS DataBase Reference :183321-74-6(CAS DataBase Reference)

Safety Information

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Description

Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity (IC50 = 2.5 μM). This inhibits tumor growth in human head and neck carcinoma (HN5) tumor xenografts in mice with an ED50 value of 9 mg/kg. Erlotinib also suppresses cyclin-dependent kinase 2 (Cdk2) activity in breast cancer cells (IC50 = 4.6 μM) and JAK2 mutant JAK2V617F (IC50 = 5 μM), which is associated with polycythemia vera, idiopathic myelofibrosis, and essential thrombocythemia. The drug form of Erlotinib, Tarceva?, is used to treat certain forms of cancer, including non-small cell lung cancer.

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