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ChemicalBook >> CAS DataBase List >> Erlotinib

Erlotinib

Erlotinib price.
  • $5 - $2776
  • Product name: Erlotinib
  • CAS: 183321-74-6
  • MF: C22H23N3O4
  • MW: 393.44
  • EINECS:689-196-2
  • MDL Number:MFCD02089651
  • Synonyms:ERLOTINIB;ERLOTINIB HCL SALT;4-[(3-ethynylphenyl)amino]-6,7-bis(2-methoxyethoxy)quinazoline;n-(3-ethynylphenyl)[6,7-bis(2-methoxyethoxy)quinazolin-4-yl]amine;Erlotinib Hydrochloirde;4-Quinazolinamine, N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)-;ERLOTININ;N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine
Price85 Properties Safety Information Description
85 prices
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  • aablocks
  • AccelPharmtech
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  • Activate Scientific
  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Apolloscientific
  • Arctom
  • AvaChem
  • Biorbyt Ltd
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  • Cayman Chemical
  • Chemenu
  • ChemScene
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  • DC Chemicals
  • Matrix Scientific
  • TCI Chemical
  • Usbiological
Package
  • 10mM*1mLinDMSO(Solid+Solvent)
  • 10mM*1mLinDMSO(Solution)
  • 5mg
  • 50mg
  • 10mM(in1mLDMSO)
  • 10mg
  • 1.00g
  • 2g
  • 5.00g
  • 10g
  • 50g
  • 1mg
  • 25mg
  • 100mg
  • 250mg
  • 1g
  • 500mg
  • 10mM(in 1mL DMSO)
  • 25g
  • 100g
  • 5g
  • 001
  • Manufactureraablocks
  • Product numberAA0027F6
  • Product descriptionN-(3-Ethynylphenyl)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine ≥98%
  • Packaging100mg
  • Price$10
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA0027F6
  • Product descriptionN-(3-Ethynylphenyl)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine 95%
  • Packaging1mg
  • Price$10
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA0027F6
  • Product descriptionN-(3-Ethynylphenyl)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine 95%
  • Packaging250mg
  • Price$13
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA0027F6
  • Product descriptionN-(3-Ethynylphenyl)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine ≥98%
  • Packaging500mg
  • Price$15
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA0027F6
  • Product descriptionN-(3-Ethynylphenyl)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine 95%
  • Packaging1g
  • Price$19
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA0027F6
  • Product descriptionN-(3-Ethynylphenyl)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine ≥95%
  • Packaging5g
  • Price$40
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA0027F6
  • Product descriptionN-(3-Ethynylphenyl)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine 98%
  • Packaging25g
  • Price$185
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA0027F6
  • Product descriptionN-(3-Ethynylphenyl)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine 98%
  • Packaging100g
  • Price$540
  • Updated2026-05-28
  • Buy
  • ManufacturerAccelPharmtech
  • Product numberAT7548
  • Product descriptionErlotinib 99%
  • Packaging25G
  • Price$180
  • Updated2026-05-21
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  • ManufacturerAccelPharmtech
  • Product number093333
  • Product descriptionErlotinib 99%
  • Packaging001
  • Price$40
  • Updated2026-05-21
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  • ManufacturerACHEMBLOCK
  • Product numberP50974
  • Product descriptionerlotinib 98%
  • Packaging5G
  • Price$40
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberP50974
  • Product descriptionerlotinib 98%
  • Packaging100MG
  • Price$10
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberP50974
  • Product descriptionerlotinib 98%
  • Packaging1G
  • Price$15
  • Updated2026-05-27
  • Buy
  • ManufacturerActivate Scientific
  • Product numberAS59585
  • Product descriptionErlotinib 95%
  • Packaging1g
  • Price$42
  • Updated2021-12-16
  • Buy
  • ManufacturerActivate Scientific
  • Product numberAS59585
  • Product descriptionErlotinib 95%
  • Packaging5G
  • Price$155
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberP443
  • Product descriptionErlotinib
  • Packaging1g
  • Price$27
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA0027F6 N-(3-Ethynylphenyl)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine ≥98% 100mg $10 2026-05-28 Buy
aablocks AA0027F6 N-(3-Ethynylphenyl)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine 95% 1mg $10 2026-05-28 Buy
aablocks AA0027F6 N-(3-Ethynylphenyl)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine 95% 250mg $13 2026-05-28 Buy
aablocks AA0027F6 N-(3-Ethynylphenyl)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine ≥98% 500mg $15 2026-05-28 Buy
aablocks AA0027F6 N-(3-Ethynylphenyl)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine 95% 1g $19 2026-05-28 Buy
aablocks AA0027F6 N-(3-Ethynylphenyl)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine ≥95% 5g $40 2026-05-28 Buy
aablocks AA0027F6 N-(3-Ethynylphenyl)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine 98% 25g $185 2026-05-28 Buy
aablocks AA0027F6 N-(3-Ethynylphenyl)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine 98% 100g $540 2026-05-28 Buy
AccelPharmtech AT7548 Erlotinib 99% 25G $180 2026-05-21 Buy
AccelPharmtech 093333 Erlotinib 99% 001 $40 2026-05-21 Buy
ACHEMBLOCK P50974 erlotinib 98% 5G $40 2026-05-27 Buy
ACHEMBLOCK P50974 erlotinib 98% 100MG $10 2026-05-27 Buy
ACHEMBLOCK P50974 erlotinib 98% 1G $15 2026-05-27 Buy
Activate Scientific AS59585 Erlotinib 95% 1g $42 2021-12-16 Buy
Activate Scientific AS59585 Erlotinib 95% 5G $155 2021-12-16 Buy
AK Scientific P443 Erlotinib 1g $27 2021-12-16 Buy
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Properties

Melting point :159-160 °C
Boiling point :553.6±50.0 °C(Predicted)
Density :1.24
storage temp. :Keep in dark place,Sealed in dry,Store in freezer, under -20°C
solubility :Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
form :Solid
pka :5.32±0.30(Predicted)
color :White
InChI :InChI=1S/C22H23N3O4/c1-4-16-6-5-7-17(12-16)25-22-18-13-20(28-10-8-26-2)21(29-11-9-27-3)14-19(18)23-15-24-22/h1,5-7,12-15H,8-11H2,2-3H3,(H,23,24,25)
InChIKey :AAKJLRGGTJKAMG-UHFFFAOYSA-N
SMILES :N1=C2C(C=C(OCCOC)C(OCCOC)=C2)=C(NC2=CC=CC(C#C)=C2)N=C1
CAS DataBase Reference :183321-74-6(CAS DataBase Reference)

Safety Information

Symbol(GHS): Health Hazard (GHS08)
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H227 Combustible liquid Flammable liquids Category 4 Warning P210, P280, P370+P378, P403+P235,P501
H304 May be fatal if swallowed and enters airways Aspiration hazard Category 1 Danger
H350 May cause cancer Carcinogenicity Category 1A, 1B Danger
Precautionary statements:
P201 Obtain special instructions before use.
P202 Do not handle until all safety precautions have been read and understood.
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P308+P313 IF exposed or concerned: Get medical advice/attention.
P331 Do NOT induce vomiting.
P370+P378 In case of fire: Use … for extinction.
P403+P235 Store in a well-ventilated place. Keep cool.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity (IC50 = 2.5 μM). This inhibits tumor growth in human head and neck carcinoma (HN5) tumor xenografts in mice with an ED50 value of 9 mg/kg. Erlotinib also suppresses cyclin-dependent kinase 2 (Cdk2) activity in breast cancer cells (IC50 = 4.6 μM) and JAK2 mutant JAK2V617F (IC50 = 5 μM), which is associated with polycythemia vera, idiopathic myelofibrosis, and essential thrombocythemia. The drug form of Erlotinib, Tarceva?, is used to treat certain forms of cancer, including non-small cell lung cancer.

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Suppliers and manufacturers

Guangzhou Isun Pharmaceutical Co., Ltd Guangzhou Tomums Life Science Co., Ltd. Shanghai Boyle Chemical Co., Ltd. J & K SCIENTIFIC LTD. INTATRADE GmbH future industrial shanghai co., ltd Chembest Research Laboratories Limited Energy Chemical Beijing Ouhe Technology Co., Ltd JinYan Chemicals(ShangHai) Co.,Ltd.