Erlotinib
|
- $5 - $1900
- Product name: Erlotinib
- CAS: 183321-74-6
- MF: C22H23N3O4
- MW: 393.44
- EINECS:689-196-2
- MDL Number:MFCD02089651
- Synonyms:ERLOTINIB;ERLOTINIB HCL SALT;4-[(3-ethynylphenyl)amino]-6,7-bis(2-methoxyethoxy)quinazoline;n-(3-ethynylphenyl)[6,7-bis(2-methoxyethoxy)quinazolin-4-yl]amine;Erlotinib Hydrochloirde;4-Quinazolinamine, N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)-;ERLOTININ;N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine
47 prices
Selected condition:
Brand
- AccelPharmtech
- Activate Scientific
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- AvaChem
- Biorbyt Ltd
- Biosynth Carbosynth
- Cayman Chemical
- Chemenu
- ChemScene
- Chemtos
- Crysdot
- DC Chemicals
Package
- 25mg
- 50mg
- 1mg
- 10mM(in 1mL DMSO)
- 001
- 100MG
- 250mg
- 500MG
- 1g
- 2g
- 5G
- 10g
- 25G
- ManufacturerAccelPharmtech
- Product number093333
- Product descriptionErlotinib 99%
- Packaging001
- Price$40
- Updated2021-12-16
- Buy
- ManufacturerAccelPharmtech
- Product numberAT7548
- Product descriptionErlotinib 99%
- Packaging25G
- Price$180
- Updated2021-12-16
- Buy
- ManufacturerActivate Scientific
- Product numberAS59585
- Product descriptionErlotinib 95%
- Packaging1g
- Price$42
- Updated2021-12-16
- Buy
- ManufacturerActivate Scientific
- Product numberAS59585
- Product descriptionErlotinib 95%
- Packaging5G
- Price$155
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberP443
- Product descriptionErlotinib
- Packaging1g
- Price$27
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA121900
- Product description4-[(3-Ethynylphenyl)amino]-6,7-bis(2-methoxyethoxy)quinazoline 95+%
- Packaging25mg
- Price$5
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA121900
- Product description4-[(3-Ethynylphenyl)amino]-6,7-bis(2-methoxyethoxy)quinazoline 95+%
- Packaging250mg
- Price$7
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA121900
- Product description4-[(3-Ethynylphenyl)amino]-6,7-bis(2-methoxyethoxy)quinazoline 95+%
- Packaging1g
- Price$14
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA121900
- Product description4-[(3-Ethynylphenyl)amino]-6,7-bis(2-methoxyethoxy)quinazoline 95+%
- Packaging5g
- Price$55
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA121900
- Product description4-[(3-Ethynylphenyl)amino]-6,7-bis(2-methoxyethoxy)quinazoline 95+%
- Packaging25g
- Price$235
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0024668
- Product descriptionERLOTINIB 95.00%
- Packaging100MG
- Price$179.55
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0024668
- Product descriptionERLOTINIB 95.00%
- Packaging500MG
- Price$701.2
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0024668
- Product descriptionERLOTINIB 95.00%
- Packaging1G
- Price$752.14
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0024668
- Product descriptionERLOTINIB 95.00%
- Packaging5G
- Price$1325.59
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA3397
- Product descriptionErlotinib
- Packaging1g
- Price$50
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA3397
- Product descriptionErlotinib
- Packaging10mM(in 1mL DMSO)
- Price$55
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AccelPharmtech | 093333 | Erlotinib 99% | 001 | $40 | 2021-12-16 | Buy |
| AccelPharmtech | AT7548 | Erlotinib 99% | 25G | $180 | 2021-12-16 | Buy |
| Activate Scientific | AS59585 | Erlotinib 95% | 1g | $42 | 2021-12-16 | Buy |
| Activate Scientific | AS59585 | Erlotinib 95% | 5G | $155 | 2021-12-16 | Buy |
| AK Scientific | P443 | Erlotinib | 1g | $27 | 2021-12-16 | Buy |
| Ambeed | A121900 | 4-[(3-Ethynylphenyl)amino]-6,7-bis(2-methoxyethoxy)quinazoline 95+% | 25mg | $5 | 2021-12-16 | Buy |
| Ambeed | A121900 | 4-[(3-Ethynylphenyl)amino]-6,7-bis(2-methoxyethoxy)quinazoline 95+% | 250mg | $7 | 2021-12-16 | Buy |
| Ambeed | A121900 | 4-[(3-Ethynylphenyl)amino]-6,7-bis(2-methoxyethoxy)quinazoline 95+% | 1g | $14 | 2021-12-16 | Buy |
| Ambeed | A121900 | 4-[(3-Ethynylphenyl)amino]-6,7-bis(2-methoxyethoxy)quinazoline 95+% | 5g | $55 | 2021-12-16 | Buy |
| Ambeed | A121900 | 4-[(3-Ethynylphenyl)amino]-6,7-bis(2-methoxyethoxy)quinazoline 95+% | 25g | $235 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0024668 | ERLOTINIB 95.00% | 100MG | $179.55 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0024668 | ERLOTINIB 95.00% | 500MG | $701.2 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0024668 | ERLOTINIB 95.00% | 1G | $752.14 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0024668 | ERLOTINIB 95.00% | 5G | $1325.59 | 2021-12-16 | Buy |
| ApexBio Technology | A3397 | Erlotinib | 1g | $50 | 2021-12-16 | Buy |
| ApexBio Technology | A3397 | Erlotinib | 10mM(in 1mL DMSO) | $55 | 2021-12-16 | Buy |
Properties
Melting point :159-160 °C
Boiling point :553.6±50.0 °C(Predicted)
Density :1.24
storage temp. :Keep in dark place,Sealed in dry,Store in freezer, under -20°C
solubility :Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
form :Solid
pka :5.32±0.30(Predicted)
color :White
InChI :InChI=1S/C22H23N3O4/c1-4-16-6-5-7-17(12-16)25-22-18-13-20(28-10-8-26-2)21(29-11-9-27-3)14-19(18)23-15-24-22/h1,5-7,12-15H,8-11H2,2-3H3,(H,23,24,25)
InChIKey :AAKJLRGGTJKAMG-UHFFFAOYSA-N
SMILES :N1=C2C(C=C(OCCOC)C(OCCOC)=C2)=C(NC2=CC=CC(C#C)=C2)N=C1
CAS DataBase Reference :183321-74-6(CAS DataBase Reference)
Boiling point :553.6±50.0 °C(Predicted)
Density :1.24
storage temp. :Keep in dark place,Sealed in dry,Store in freezer, under -20°C
solubility :Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
form :Solid
pka :5.32±0.30(Predicted)
color :White
InChI :InChI=1S/C22H23N3O4/c1-4-16-6-5-7-17(12-16)25-22-18-13-20(28-10-8-26-2)21(29-11-9-27-3)14-19(18)23-15-24-22/h1,5-7,12-15H,8-11H2,2-3H3,(H,23,24,25)
InChIKey :AAKJLRGGTJKAMG-UHFFFAOYSA-N
SMILES :N1=C2C(C=C(OCCOC)C(OCCOC)=C2)=C(NC2=CC=CC(C#C)=C2)N=C1
CAS DataBase Reference :183321-74-6(CAS DataBase Reference)
Safety Information
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| Signal word: | Danger | ||||||||||||||||||||||||||||
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Description
Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity (IC50 = 2.5 μM). This inhibits tumor growth in human head and neck carcinoma (HN5) tumor xenografts in mice with an ED50 value of 9 mg/kg. Erlotinib also suppresses cyclin-dependent kinase 2 (Cdk2) activity in breast cancer cells (IC50 = 4.6 μM) and JAK2 mutant JAK2V617F (IC50 = 5 μM), which is associated with polycythemia vera, idiopathic myelofibrosis, and essential thrombocythemia. The drug form of Erlotinib, Tarceva?, is used to treat certain forms of cancer, including non-small cell lung cancer.Related product price
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Suppliers and manufacturers
Capot Chemical Co.,Ltd.
Beijing Cooperate Pharmaceutical Co.,Ltd
Henan Tianfu Chemical Co.,Ltd.
Nanjing ChemLin Chemical Industry Co., Ltd.
Shanghai Yingrui Biopharma Co., Ltd.
ATK CHEMICAL COMPANY LIMITED
Anqing Chico Pharmaceutical Co., Ltd.




