Everolimus
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- $8 - $3165
- Product name: Everolimus
- CAS: 159351-69-6
- MF: C53H83NO14
- MW: 958.22
- EINECS:621-003-9
- MDL Number:MFCD00929329
- Synonyms:Rapamycin, 42-O-(2-hydroxyethyl)-;Everolimus;Certican;CERTICAN(R);EveroliMus(RAD-001);(1R,9S,12S,15R,16Z,18R,19R,21R,23S,24Z,26Z,28Z,30S,32S,35R)-1,18-dihydroxy-12-[(2R)-1-[(1S,3R,4R)-4-(2-hydroxyethoxy)-3-Methoxycyclohexyl]propan-2-yl]-19,30-diMethoxy-15,17,21,23,29,35-hexaMethyl-11,36-dioxa-4-azatricyclo[30.3.1.0^{4,9}]hexatriaconta-16,2;EveroliMus API;23,27-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclohentriacontine, rapamycin deriv
156 prices
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Brand
- aablocks
- ACHEMBLOCK
- Adipogen Life Sciences
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- AvaChem
- Biorbyt Ltd
- Biosynth
- Cayman Chemical
- ChemScene
- Crysdot
- CSNpharm
- DC Chemicals
- IsoSciences
- Labseeker
- Matrix Scientific
- Medical Isotopes, Inc.
- Sigma-Aldrich
- Thermo Scientific Chemicals
- Tocris
- TRC
- Usbiological
Package
- 1mg
- Y0002063
- Y0002061
- 1unit
- 5mg
- 10mg
- 10mM*1mLinDMSO
- 20mg
- 25mg
- 50mg
- 0.05g
- 0.1g
- 100mg
- 200mg
- 0.25g
- 10
- Y0002048
- 250.00mg
- 250mg
- 1.00g
- EvaluationSample
- 1ml
- 1g
- 10g
- 10 mg
- 70 mg
- 300mg
- 500mg
- 0.5g
- 10mM(in1mLDMSO)
- 50 mg
- 10mM(1mLinDMSO)
- 10mM(in 1mL DMSO)
- Manufactureraablocks
- Product numberAA001QJO
- Product description40-O-(2-Hydroxyethyl)rapamycin ≥98%
- Packaging5mg
- Price$16
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA001QJO
- Product description40-O-(2-Hydroxyethyl)rapamycin ≥98%
- Packaging25mg
- Price$40
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA001QJO
- Product description40-O-(2-Hydroxyethyl)rapamycin 98%
- Packaging50mg
- Price$54
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA001QJO
- Product description40-O-(2-Hydroxyethyl)rapamycin 98%
- Packaging100mg
- Price$76
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA001QJO
- Product description40-O-(2-Hydroxyethyl)rapamycin 98%
- Packaging250mg
- Price$123
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA001QJO
- Product description40-O-(2-Hydroxyethyl)rapamycin 98%
- Packaging1g
- Price$324
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA001QJO
- Product description40-O-(2-Hydroxyethyl)rapamycin 95%
- Packaging10g
- Price$3165
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product number10532
- Product descriptionEverolimus 98%
- Packaging1G
- Price$450
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product number10532
- Product descriptionEverolimus 98%
- Packaging100MG
- Price$90
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product number10532
- Product descriptionEverolimus 98%
- Packaging25MG
- Price$35
- Updated2026-05-27
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberAG-CN2-0520-M001
- Product descriptionEverolimus ≥97%(HPLC)
- Packaging1mg
- Price$30
- Updated2026-05-06
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberAG-CN2-0520-M005
- Product descriptionEverolimus ≥97%(HPLC)
- Packaging5mg
- Price$50
- Updated2026-05-06
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberAG-CN2-0520-M025
- Product descriptionEverolimus ≥97%(HPLC)
- Packaging25mg
- Price$110
- Updated2026-05-06
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberCDX-E0074-M100
- Product descriptionEverolimus ≥99%(HPLC)
- Packaging100mg
- Price$514
- Updated2026-05-06
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberCDX-E0074-M250
- Product descriptionEverolimus ≥99%(HPLC)
- Packaging250mg
- Price$882
- Updated2021-12-16
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberCDX-E0074-M250
- Product descriptionEverolimus ≥99%(HPLC)
- Packaging250mg
- Price$986
- Updated2026-05-06
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA001QJO | 40-O-(2-Hydroxyethyl)rapamycin ≥98% | 5mg | $16 | 2026-05-28 | Buy |
| aablocks | AA001QJO | 40-O-(2-Hydroxyethyl)rapamycin ≥98% | 25mg | $40 | 2026-05-28 | Buy |
| aablocks | AA001QJO | 40-O-(2-Hydroxyethyl)rapamycin 98% | 50mg | $54 | 2026-05-28 | Buy |
| aablocks | AA001QJO | 40-O-(2-Hydroxyethyl)rapamycin 98% | 100mg | $76 | 2026-05-28 | Buy |
| aablocks | AA001QJO | 40-O-(2-Hydroxyethyl)rapamycin 98% | 250mg | $123 | 2026-05-28 | Buy |
| aablocks | AA001QJO | 40-O-(2-Hydroxyethyl)rapamycin 98% | 1g | $324 | 2026-05-28 | Buy |
| aablocks | AA001QJO | 40-O-(2-Hydroxyethyl)rapamycin 95% | 10g | $3165 | 2026-05-28 | Buy |
| ACHEMBLOCK | 10532 | Everolimus 98% | 1G | $450 | 2026-05-27 | Buy |
| ACHEMBLOCK | 10532 | Everolimus 98% | 100MG | $90 | 2026-05-27 | Buy |
| ACHEMBLOCK | 10532 | Everolimus 98% | 25MG | $35 | 2026-05-27 | Buy |
| Adipogen Life Sciences | AG-CN2-0520-M001 | Everolimus ≥97%(HPLC) | 1mg | $30 | 2026-05-06 | Buy |
| Adipogen Life Sciences | AG-CN2-0520-M005 | Everolimus ≥97%(HPLC) | 5mg | $50 | 2026-05-06 | Buy |
| Adipogen Life Sciences | AG-CN2-0520-M025 | Everolimus ≥97%(HPLC) | 25mg | $110 | 2026-05-06 | Buy |
| Adipogen Life Sciences | CDX-E0074-M100 | Everolimus ≥99%(HPLC) | 100mg | $514 | 2026-05-06 | Buy |
| Adipogen Life Sciences | CDX-E0074-M250 | Everolimus ≥99%(HPLC) | 250mg | $882 | 2021-12-16 | Buy |
| Adipogen Life Sciences | CDX-E0074-M250 | Everolimus ≥99%(HPLC) | 250mg | $986 | 2026-05-06 | Buy |
Properties
Melting point :NA
Boiling point :998.7±75.0 °C(Predicted)
Density :1.18±0.1 g/cm3(Predicted)
Flash point :2℃
storage temp. :-20°C
solubility :Soluble in DMSO (up to 100 mg/ml) or in Ethanol (up to 100 mg/ml).
form :solid
pka :10.40±0.70(Predicted)
color :White
Water Solubility :Soluble in dimethysulfoxide,ethanol and chloroform. Slightly soluble in water.
Stability :Hygroscopic
Major Application :pharmaceutical
InChIKey :HKVAMNSJSFKALM-GKUWKFKPSA-N
Boiling point :998.7±75.0 °C(Predicted)
Density :1.18±0.1 g/cm3(Predicted)
Flash point :2℃
storage temp. :-20°C
solubility :Soluble in DMSO (up to 100 mg/ml) or in Ethanol (up to 100 mg/ml).
form :solid
pka :10.40±0.70(Predicted)
color :White
Water Solubility :Soluble in dimethysulfoxide,ethanol and chloroform. Slightly soluble in water.
Stability :Hygroscopic
Major Application :pharmaceutical
InChIKey :HKVAMNSJSFKALM-GKUWKFKPSA-N
Safety Information
| Symbol(GHS): |
 
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| Signal word: | Warning | ||||||||||||||||||||||||||||
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Description
Everolimus is a Kinase Inhibitor. It’s brand name is Afinitor. Everolimus is a derivative of the natural macrocyclic lactone sirolimus with immunosuppressant and anti-angiogenic properties.The mechanism of action of everolimus is as a Protein Kinase Inhibitor, and Cytochrome P450 3A4 Inhibitor, and P-Glycoprotein Inhibitor, and Cytochrome P450 2D6 Inhibitor.In cells, everolimus binds to the immunophilin FK Binding Protein-12 (FKBP-12) to generate an immunosuppressive complex that binds to and inhibits the activation of the mammalian Target of Rapamycin (mTOR), a key regulatory kinase. Inhibition of mTOR activation results in the inhibition of T lymphocyte activation and proliferation associated with antigen and cytokine (IL-2, IL-4, and IL-15) stimulation and the inhibition of antibody production.
Everolimus is a biological therapy treatment for
Advanced breast cancer if you have been through the menopause (post menopausal). You take it with the hormone therapy drug exemestane
Advanced kidney cancer that has come back either during or after treatment.
Neuroendocrine tumours of the pancreas that can't be removed with surgery or have spread (metastatic disease).
Researchers are also looking at everolimus as a treatment for head and neck cancer and cancer of the food pipe (oesophageal cancer).
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Suppliers and manufacturers
Shaanxi Haibo Biotechnology Co., Ltd
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BEIJING SJAR TECHNOLOGY DEVELOPMENT CO., LTD.
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Xi an Biohorlden Industry Trade Co Ltd
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Wuhan JiyunZen Tech Co., Ltd.
AFINE CHEMICALS LIMITED
Seasons Biotechnology Co., Ltd.
Capot Chemical Co.,Ltd.
Beijing Cooperate Pharmaceutical Co.,Ltd
Henan Tianfu Chemical Co.,Ltd.
Everolimus
CAS:159351-69-6