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ChemicalBook >> CAS DataBase List >> FGF-401

FGF-401

FGF-401 price.
  • $34 - $2400
  • Product name: FGF-401
  • CAS: 1708971-55-4
  • MF: C25H30N8O4
  • MW: 506.56
  • EINECS:-0
  • MDL Number:MFCD31381923
  • Synonyms:8-naphthyridine-1(2H)-carboxamide;0997;FGF-401;N-(5-cyano-4-((2-methoxyethyl)amino)pyridin-2-yl)-7-formyl-6-((4-methyl-2-oxopiperazin-1-yl)methyl)-3,4-dihydro-1,8-naphthyridine-1(2H)-carboxamide;N-[5-cyano-4-(2-methoxyethylamino)pyridin-2-yl]-7-formyl-6-[(4-methyl-2-oxopiperazin-1-yl)methyl]-3,4-dihydro-2~{H}-1,8-naphthyridine-1-carboxamide;Roblitinib（FGF-401）;FGF 401;FGF-401;N-[5-Cyano-4-[(2-methoxyethyl)amino]-2-pyridinyl]-7-formyl-3,4-dihydro-6-[(4-methyl-2-oxo-1-piperazinyl)methyl]-1,8-naphthyridine-1(2H)-carboxamide
Price41 Properties Safety Information Description
41 prices
Selected condition：
Brand
  • aablocks
  • AK Scientific
  • American Custom Chemicals Corporation
  • Arctom
  • Axon Medchem
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • DC Chemicals
Package
  • 10mM*1mLinDMSO
  • 1mg
  • 2mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 1g
  • Manufactureraablocks
  • Product numberAA003AON
  • Product descriptionN-[5-Cyano-4-[(2-methoxyethyl)amino]-2-pyridinyl]-7-formyl-3,4-dihydro-6-[(4-methyl-2-oxo-1-piperazinyl)methyl]-1,8-naphthyridine-1(2H)-carboxamide 98%
  • Packaging5mg
  • Price$50
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA003AON
  • Product descriptionN-[5-Cyano-4-[(2-methoxyethyl)amino]-2-pyridinyl]-7-formyl-3,4-dihydro-6-[(4-methyl-2-oxo-1-piperazinyl)methyl]-1,8-naphthyridine-1(2H)-carboxamide 98%
  • Packaging10mg
  • Price$74
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA003AON
  • Product descriptionN-[5-Cyano-4-[(2-methoxyethyl)amino]-2-pyridinyl]-7-formyl-3,4-dihydro-6-[(4-methyl-2-oxo-1-piperazinyl)methyl]-1,8-naphthyridine-1(2H)-carboxamide 98%
  • Packaging2mg
  • Price$34
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA003AON
  • Product descriptionN-[5-Cyano-4-[(2-methoxyethyl)amino]-2-pyridinyl]-7-formyl-3,4-dihydro-6-[(4-methyl-2-oxo-1-piperazinyl)methyl]-1,8-naphthyridine-1(2H)-carboxamide 98%
  • Packaging25mg
  • Price$125
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA003AON
  • Product descriptionN-[5-Cyano-4-[(2-methoxyethyl)amino]-2-pyridinyl]-7-formyl-3,4-dihydro-6-[(4-methyl-2-oxo-1-piperazinyl)methyl]-1,8-naphthyridine-1(2H)-carboxamide 98%
  • Packaging50mg
  • Price$192
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA003AON
  • Product descriptionN-[5-Cyano-4-[(2-methoxyethyl)amino]-2-pyridinyl]-7-formyl-3,4-dihydro-6-[(4-methyl-2-oxo-1-piperazinyl)methyl]-1,8-naphthyridine-1(2H)-carboxamide 98%
  • Packaging100mg
  • Price$315
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA003AON
  • Product descriptionN-[5-Cyano-4-[(2-methoxyethyl)amino]-2-pyridinyl]-7-formyl-3,4-dihydro-6-[(4-methyl-2-oxo-1-piperazinyl)methyl]-1,8-naphthyridine-1(2H)-carboxamide 95%
  • Packaging250mg
  • Price$555
  • Updated2026-05-28
  • Buy
  • ManufacturerAK Scientific
  • Product number2323EF
  • Product descriptionRoblitinib
  • Packaging1mg
  • Price$139
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0005698
  • Product descriptionN-(5-CYANO-4-((2-METHOXYETHYL)AMINO)PYRIDIN-2-YL)-7-FORMYL-6-((4-METHYL-2-OXOPIPERAZIN-1-YL)METHYL)-3,4-DIHYDRO-1,8-NAPHTHYRIDINE-1(2H)-CARBOXAMIDE 95.00%
  • Packaging5MG
  • Price$454.85
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberHY-101568
  • Product descriptionRoblitinib 99.67%
  • Packaging5mg
  • Price$124
  • Updated2026-05-26
  • Buy
  • ManufacturerArctom
  • Product numberHY-101568
  • Product descriptionRoblitinib 99.67%
  • Packaging50mg
  • Price$589
  • Updated2026-05-26
  • Buy
  • ManufacturerArctom
  • Product numberHY-101568
  • Product descriptionRoblitinib 99.67%
  • Packaging10mg
  • Price$200
  • Updated2026-05-26
  • Buy
  • ManufacturerArctom
  • Product numberHY-101568
  • Product descriptionRoblitinib 99.67%
  • Packaging2mg
  • Price$91
  • Updated2026-05-26
  • Buy
  • ManufacturerArctom
  • Product numberHY-101568
  • Product descriptionRoblitinib 99.67%
  • Packaging100mg
  • Price$903
  • Updated2026-05-26
  • Buy
  • ManufacturerArctom
  • Product numberHY-101568
  • Product descriptionRoblitinib 99.67%
  • Packaging25mg
  • Price$368
  • Updated2026-05-26
  • Buy
  • ManufacturerAxon Medchem
  • Product numberAxon2953
  • Product descriptionRoblitinib
  • Packaging5mg
  • Price$137.5
  • Updated2026-05-19
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA003AON N-[5-Cyano-4-[(2-methoxyethyl)amino]-2-pyridinyl]-7-formyl-3,4-dihydro-6-[(4-methyl-2-oxo-1-piperazinyl)methyl]-1,8-naphthyridine-1(2H)-carboxamide 98% 5mg $50 2026-05-28 Buy
aablocks AA003AON N-[5-Cyano-4-[(2-methoxyethyl)amino]-2-pyridinyl]-7-formyl-3,4-dihydro-6-[(4-methyl-2-oxo-1-piperazinyl)methyl]-1,8-naphthyridine-1(2H)-carboxamide 98% 10mg $74 2026-05-28 Buy
aablocks AA003AON N-[5-Cyano-4-[(2-methoxyethyl)amino]-2-pyridinyl]-7-formyl-3,4-dihydro-6-[(4-methyl-2-oxo-1-piperazinyl)methyl]-1,8-naphthyridine-1(2H)-carboxamide 98% 2mg $34 2026-05-28 Buy
aablocks AA003AON N-[5-Cyano-4-[(2-methoxyethyl)amino]-2-pyridinyl]-7-formyl-3,4-dihydro-6-[(4-methyl-2-oxo-1-piperazinyl)methyl]-1,8-naphthyridine-1(2H)-carboxamide 98% 25mg $125 2026-05-28 Buy
aablocks AA003AON N-[5-Cyano-4-[(2-methoxyethyl)amino]-2-pyridinyl]-7-formyl-3,4-dihydro-6-[(4-methyl-2-oxo-1-piperazinyl)methyl]-1,8-naphthyridine-1(2H)-carboxamide 98% 50mg $192 2026-05-28 Buy
aablocks AA003AON N-[5-Cyano-4-[(2-methoxyethyl)amino]-2-pyridinyl]-7-formyl-3,4-dihydro-6-[(4-methyl-2-oxo-1-piperazinyl)methyl]-1,8-naphthyridine-1(2H)-carboxamide 98% 100mg $315 2026-05-28 Buy
aablocks AA003AON N-[5-Cyano-4-[(2-methoxyethyl)amino]-2-pyridinyl]-7-formyl-3,4-dihydro-6-[(4-methyl-2-oxo-1-piperazinyl)methyl]-1,8-naphthyridine-1(2H)-carboxamide 95% 250mg $555 2026-05-28 Buy
AK Scientific 2323EF Roblitinib 1mg $139 2021-12-16 Buy
American Custom Chemicals Corporation INB0005698 N-(5-CYANO-4-((2-METHOXYETHYL)AMINO)PYRIDIN-2-YL)-7-FORMYL-6-((4-METHYL-2-OXOPIPERAZIN-1-YL)METHYL)-3,4-DIHYDRO-1,8-NAPHTHYRIDINE-1(2H)-CARBOXAMIDE 95.00% 5MG $454.85 2021-12-16 Buy
Arctom HY-101568 Roblitinib 99.67% 5mg $124 2026-05-26 Buy
Arctom HY-101568 Roblitinib 99.67% 50mg $589 2026-05-26 Buy
Arctom HY-101568 Roblitinib 99.67% 10mg $200 2026-05-26 Buy
Arctom HY-101568 Roblitinib 99.67% 2mg $91 2026-05-26 Buy
Arctom HY-101568 Roblitinib 99.67% 100mg $903 2026-05-26 Buy
Arctom HY-101568 Roblitinib 99.67% 25mg $368 2026-05-26 Buy
Axon Medchem Axon2953 Roblitinib 5mg $137.5 2026-05-19 Buy
Next Last

Properties

Boiling point :852.1±65.0 °C(Predicted)
Density :1.39±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMSO:5.4(Max Conc. mg/mL);10.66(Max Conc. mM)
Chloroform:30.0(Max Conc. mg/mL);59.22(Max Conc. mM) form :A crystalline solid
pka :11.40±0.20(Predicted)
color :White to off-white
InChIKey :BHKDKKZMPODMIQ-UHFFFAOYSA-N
SMILES :N1(C(NC2=NC=C(C#N)C(NCCOC)=C2)=O)C2C(=CC(CN3CCN(C)CC3=O)=C(C=O)N=2)CCC1

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312 Call a POISON CENTER or doctor/physician if you feel unwell.
P321 Specific treatment (see … on this label).
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P362 Take off contaminated clothing and wash before reuse.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

FGF401 is an inhibitor of FGF receptor 4 (FGFR4; IC50 = 1.9 nM). It inhibits proliferation of Huh7 carcinoma cells with an IC50 value of 12 nM. FGF401 induces bile acid synthesis in dogs, increasing plasma and fecal levels of bile acids when administered at a dose of 45 mg/kg per day for four weeks. It also decreases serum cholesterol when administered at doses ranging from 5 to 45 mg/kg per day.

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