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ChemicalBook >> CAS DataBase List >> FIIN-2

FIIN-2

FIIN-2 price.
  • $34 - $1800
  • Product name: FIIN-2
  • CAS: 1633044-56-0
  • MF: C35H38N8O4
  • MW: 634.73
  • EINECS:
  • MDL Number:MFCD28386553
  • Synonyms:FIN-2;N-[4-[[3-(3,5-Dimethoxyphenyl)-3,4-dihydro-7-[[4-(4-methyl-1-piperazinyl)phenyl]amino]-2-oxopyrimido[4,5-d]pyrimidin-1(2H)-yl]methyl]phenyl]-2-propenamide;FIIN-2;2-Propenamide, N-[4-[[3-(3,5-dimethoxyphenyl)-3,4-dihydro-7-[[4-(4-methyl-1-piperazinyl)phenyl]amino]-2-oxopyrimido[4,5-d]pyrimidin-1(2H)-yl]methyl]phenyl]-;CS-1618;FIIN2;FIIN-2;FIIN 2;inhibit,FGFR,FIIN2,FIIN 2,Fibroblast growth factor receptor,Inhibitor,FIIN-2;FIIN-2, 10 mM in DMSO
Price43 Properties Safety Information Description
43 prices
Selected condition：
Brand
  • aablocks
  • ACHEMBLOCK
  • AK Scientific
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Arctom
  • Biorbyt Ltd
  • Biosynth
  • Cayman Chemical
  • ChemScene
  • DC Chemicals
  • TRC
Package
  • 10mM*1mLinDMSO(Solid+Solvent)
  • 10mM*1mLinDMSO(Solution)
  • 2mg
  • 10mM(in1mLDMSO)
  • 1g
  • 10mM*1mLinDMSO
  • 250mg
  • 1mg
  • 5mg
  • 10mg
  • 100MG
  • 25mg
  • 50mg
  • 10mM(in 1mL DMSO)
  • Manufactureraablocks
  • Product numberAA00ABMX
  • Product descriptionN-[4-[[3-(3,5-Dimethoxyphenyl)-3,4-dihydro-7-[[4-(4-methyl-1-piperazinyl)phenyl]amino]-2-oxopyrimido[4,5-d]pyrimidin-1(2H)-yl]methyl]phenyl]-2-propenamide 99%
  • Packaging1mg
  • Price$34
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00ABMX
  • Product descriptionN-[4-[[3-(3,5-Dimethoxyphenyl)-3,4-dihydro-7-[[4-(4-methyl-1-piperazinyl)phenyl]amino]-2-oxopyrimido[4,5-d]pyrimidin-1(2H)-yl]methyl]phenyl]-2-propenamide 99%
  • Packaging5mg
  • Price$47
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00ABMX
  • Product descriptionN-[4-[[3-(3,5-Dimethoxyphenyl)-3,4-dihydro-7-[[4-(4-methyl-1-piperazinyl)phenyl]amino]-2-oxopyrimido[4,5-d]pyrimidin-1(2H)-yl]methyl]phenyl]-2-propenamide 99%
  • Packaging10mg
  • Price$75
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00ABMX
  • Product descriptionN-[4-[[3-(3,5-Dimethoxyphenyl)-3,4-dihydro-7-[[4-(4-methyl-1-piperazinyl)phenyl]amino]-2-oxopyrimido[4,5-d]pyrimidin-1(2H)-yl]methyl]phenyl]-2-propenamide 99%
  • Packaging25mg
  • Price$149
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00ABMX
  • Product descriptionN-[4-[[3-(3,5-Dimethoxyphenyl)-3,4-dihydro-7-[[4-(4-methyl-1-piperazinyl)phenyl]amino]-2-oxopyrimido[4,5-d]pyrimidin-1(2H)-yl]methyl]phenyl]-2-propenamide 99%
  • Packaging50mg
  • Price$224
  • Updated2026-05-28
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberM15646
  • Product descriptionFIIN-2 98%
  • Packaging25MG
  • Price$250
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberM15646
  • Product descriptionFIIN-2 98%
  • Packaging100MG
  • Price$935
  • Updated2026-05-27
  • Buy
  • ManufacturerAK Scientific
  • Product number2833EC
  • Product descriptionN-[4-[[3-(3,5-Dimethoxyphenyl)-7-[4-(4-methylpiperazin-1-yl)anilino]-2-oxo-4H-pyrimido[4,5-d]pyrimidin-1-yl]methyl]phenyl]prop-2-enamide
  • Packaging1mg
  • Price$147
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0004690
  • Product descriptionFIIN-2 95.00%
  • Packaging5MG
  • Price$499.51
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8696
  • Product descriptionFIIN-2
  • Packaging25mg
  • Price$345
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8696
  • Product descriptionFIIN-2
  • Packaging10mM(in 1mL DMSO)
  • Price$142
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8696
  • Product descriptionFIIN-2
  • Packaging10mM(in1mLDMSO)
  • Price$121
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8696
  • Product descriptionFIIN-2
  • Packaging5mg
  • Price$102
  • Updated2026-05-06
  • Buy
  • ManufacturerArctom
  • Product numberHY-18602
  • Product descriptionFIIN-2 99.32%
  • Packaging5mg
  • Price$113
  • Updated2026-05-26
  • Buy
  • ManufacturerArctom
  • Product numberHY-18602
  • Product descriptionFIIN-2 99.32%
  • Packaging1mg
  • Price$56
  • Updated2026-05-26
  • Buy
  • ManufacturerArctom
  • Product numberHY-18602
  • Product descriptionFIIN-2 99.32%
  • Packaging10mM*1mLinDMSO(Solid+Solvent)
  • Price$150
  • Updated2026-05-26
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA00ABMX N-[4-[[3-(3,5-Dimethoxyphenyl)-3,4-dihydro-7-[[4-(4-methyl-1-piperazinyl)phenyl]amino]-2-oxopyrimido[4,5-d]pyrimidin-1(2H)-yl]methyl]phenyl]-2-propenamide 99% 1mg $34 2026-05-28 Buy
aablocks AA00ABMX N-[4-[[3-(3,5-Dimethoxyphenyl)-3,4-dihydro-7-[[4-(4-methyl-1-piperazinyl)phenyl]amino]-2-oxopyrimido[4,5-d]pyrimidin-1(2H)-yl]methyl]phenyl]-2-propenamide 99% 5mg $47 2026-05-28 Buy
aablocks AA00ABMX N-[4-[[3-(3,5-Dimethoxyphenyl)-3,4-dihydro-7-[[4-(4-methyl-1-piperazinyl)phenyl]amino]-2-oxopyrimido[4,5-d]pyrimidin-1(2H)-yl]methyl]phenyl]-2-propenamide 99% 10mg $75 2026-05-28 Buy
aablocks AA00ABMX N-[4-[[3-(3,5-Dimethoxyphenyl)-3,4-dihydro-7-[[4-(4-methyl-1-piperazinyl)phenyl]amino]-2-oxopyrimido[4,5-d]pyrimidin-1(2H)-yl]methyl]phenyl]-2-propenamide 99% 25mg $149 2026-05-28 Buy
aablocks AA00ABMX N-[4-[[3-(3,5-Dimethoxyphenyl)-3,4-dihydro-7-[[4-(4-methyl-1-piperazinyl)phenyl]amino]-2-oxopyrimido[4,5-d]pyrimidin-1(2H)-yl]methyl]phenyl]-2-propenamide 99% 50mg $224 2026-05-28 Buy
ACHEMBLOCK M15646 FIIN-2 98% 25MG $250 2026-05-27 Buy
ACHEMBLOCK M15646 FIIN-2 98% 100MG $935 2026-05-27 Buy
AK Scientific 2833EC N-[4-[[3-(3,5-Dimethoxyphenyl)-7-[4-(4-methylpiperazin-1-yl)anilino]-2-oxo-4H-pyrimido[4,5-d]pyrimidin-1-yl]methyl]phenyl]prop-2-enamide 1mg $147 2021-12-16 Buy
American Custom Chemicals Corporation INB0004690 FIIN-2 95.00% 5MG $499.51 2021-12-16 Buy
ApexBio Technology A8696 FIIN-2 25mg $345 2026-05-06 Buy
ApexBio Technology A8696 FIIN-2 10mM(in 1mL DMSO) $142 2021-12-16 Buy
ApexBio Technology A8696 FIIN-2 10mM(in1mLDMSO) $121 2026-05-06 Buy
ApexBio Technology A8696 FIIN-2 5mg $102 2026-05-06 Buy
Arctom HY-18602 FIIN-2 99.32% 5mg $113 2026-05-26 Buy
Arctom HY-18602 FIIN-2 99.32% 1mg $56 2026-05-26 Buy
Arctom HY-18602 FIIN-2 99.32% 10mM*1mLinDMSO(Solid+Solvent) $150 2026-05-26 Buy
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Properties

Density :1.306±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :≥31.75 mg/mL in DMSO; insoluble in H2O; ≥3.39 mg/mL in EtOH with gentle warming
form :solid
pka :13.51±0.70(Predicted)
color :White to off-white

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

FIIN-2 is an irreversible FGFR inhibitor with IC50 values of 3.09, 4.3, 27, and 45.3 nM for FGFR1, FGFR2, FGFR3, and FGFR4, respectively. It has been shown to inhibit cell proliferation of transformed Ba/F3 cell lines and demonstrates antiproliferative activity in cells dependent upon the gatekeeper mutants of FGFR1 or FGFR2. By inhibiting FGFR in a zebrafish developmental model, FIIN-2 caused mild to severe alterations in tail morphogenesis similar to the phenotypes reported following genetic knockdown of FGFR.

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Suppliers and manufacturers

Shanghai Boyle Chemical Co., Ltd. Dalian Meilun Biotech Co., Ltd. Haoyuan Chemexpress Co., Ltd. MedChemexpress LLC Bide Pharmatech Ltd. AdooQ Bioscience CHINA Shanghai Lollane Biological Technology Co.,Ltd. ShangHai Siyan Biological Technology Co., Ltd. Shanghai EFE Biological Technology Co., Ltd. Shanghai YuanYe Biotechnology Co., Ltd.