FIIN-2
|
- $44 - $1800
- Product name: FIIN-2
- CAS: 1633044-56-0
- MF: C35H38N8O4
- MW: 634.73
- EINECS:
- MDL Number:MFCD28386553
- Synonyms:FIN-2;N-[4-[[3-(3,5-Dimethoxyphenyl)-3,4-dihydro-7-[[4-(4-methyl-1-piperazinyl)phenyl]amino]-2-oxopyrimido[4,5-d]pyrimidin-1(2H)-yl]methyl]phenyl]-2-propenamide;FIIN-2;2-Propenamide, N-[4-[[3-(3,5-dimethoxyphenyl)-3,4-dihydro-7-[[4-(4-methyl-1-piperazinyl)phenyl]amino]-2-oxopyrimido[4,5-d]pyrimidin-1(2H)-yl]methyl]phenyl]-;CS-1618;FIIN2;FIIN-2;FIIN 2;inhibit,FGFR,FIIN2,FIIN 2,Fibroblast growth factor receptor,Inhibitor,FIIN-2
12 prices
Selected condition：
Brand
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Cayman Chemical
- ChemScene
- DC Chemicals
- TRC
Package
- 1mg
- 5MG
- 10mg
- 25mg
- 50mg
- 100mg
- 1g
- 10mM(in 1mL DMSO)
- ManufacturerAK Scientific
- Product number2833EC
- Product descriptionN-[4-[[3-(3,5-Dimethoxyphenyl)-7-[4-(4-methylpiperazin-1-yl)anilino]-2-oxo-4H-pyrimido[4,5-d]pyrimidin-1-yl]methyl]phenyl]prop-2-enamide
- Packaging1mg
- Price$147
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0004690
- Product descriptionFIIN-2 95.00%
- Packaging5MG
- Price$499.51
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8696
- Product descriptionFIIN-2
- Packaging10mM(in 1mL DMSO)
- Price$142
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number19837
- Product descriptionFIIN-2 ≥98%
- Packaging1mg
- Price$44
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number19837
- Product descriptionFIIN-2 ≥98%
- Packaging5mg
- Price$151
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number19837
- Product descriptionFIIN-2 ≥98%
- Packaging10mg
- Price$278
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number19837
- Product descriptionFIIN-2 ≥98%
- Packaging25mg
- Price$533
- Updated2024-03-01
- Buy
- ManufacturerChemScene
- Product numberCS-5343
- Product descriptionFIIN-2 99.95%
- Packaging5mg
- Price$122
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-5343
- Product descriptionFIIN-2 99.95%
- Packaging50mg
- Price$660
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC8330
- Product descriptionFIIN-2 >98%
- Packaging100mg
- Price$500
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC8330
- Product descriptionFIIN-2 >98%
- Packaging1g
- Price$1800
- Updated2021-12-16
- Buy
- ManufacturerTRC
- Product numberF336505
- Product descriptionFIIN2
- Packaging5mg
- Price$275
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 2833EC | N-[4-[[3-(3,5-Dimethoxyphenyl)-7-[4-(4-methylpiperazin-1-yl)anilino]-2-oxo-4H-pyrimido[4,5-d]pyrimidin-1-yl]methyl]phenyl]prop-2-enamide | 1mg | $147 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | INB0004690 | FIIN-2 95.00% | 5MG | $499.51 | 2021-12-16 | Buy |
| ApexBio Technology | A8696 | FIIN-2 | 10mM(in 1mL DMSO) | $142 | 2021-12-16 | Buy |
| Cayman Chemical | 19837 | FIIN-2 ≥98% | 1mg | $44 | 2024-03-01 | Buy |
| Cayman Chemical | 19837 | FIIN-2 ≥98% | 5mg | $151 | 2024-03-01 | Buy |
| Cayman Chemical | 19837 | FIIN-2 ≥98% | 10mg | $278 | 2024-03-01 | Buy |
| Cayman Chemical | 19837 | FIIN-2 ≥98% | 25mg | $533 | 2024-03-01 | Buy |
| ChemScene | CS-5343 | FIIN-2 99.95% | 5mg | $122 | 2021-12-16 | Buy |
| ChemScene | CS-5343 | FIIN-2 99.95% | 50mg | $660 | 2021-12-16 | Buy |
| DC Chemicals | DC8330 | FIIN-2 >98% | 100mg | $500 | 2021-12-16 | Buy |
| DC Chemicals | DC8330 | FIIN-2 >98% | 1g | $1800 | 2021-12-16 | Buy |
| TRC | F336505 | FIIN2 | 5mg | $275 | 2021-12-16 | Buy |
Properties
Density :1.306±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :≥31.75 mg/mL in DMSO; insoluble in H2O; ≥3.39 mg/mL in EtOH with gentle warming
form :solid
pka :13.51±0.70(Predicted)
storage temp. :Store at -20°C
solubility :≥31.75 mg/mL in DMSO; insoluble in H2O; ≥3.39 mg/mL in EtOH with gentle warming
form :solid
pka :13.51±0.70(Predicted)
Safety Information
| Symbol(GHS): |
|
|||||||||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Signal word: | Warning | |||||||||||||||||||||||||||||||||||
| Hazard statements: |
|
|||||||||||||||||||||||||||||||||||
| Precautionary statements: |
|
Description
FIIN-2 is an irreversible FGFR inhibitor with IC50 values of 3.09, 4.3, 27, and 45.3 nM for FGFR1, FGFR2, FGFR3, and FGFR4, respectively. It has been shown to inhibit cell proliferation of transformed Ba/F3 cell lines and demonstrates antiproliferative activity in cells dependent upon the gatekeeper mutants of FGFR1 or FGFR2. By inhibiting FGFR in a zebrafish developmental model, FIIN-2 caused mild to severe alterations in tail morphogenesis similar to the phenotypes reported following genetic knockdown of FGFR.Suppliers and manufacturers
Career Henan Chemica Co
InvivoChem
Nantong HI-FUTURE Biology Co., Ltd.
TargetMol Chemicals Inc.
ShenZhen Trendseen Biological Technology Co.,Ltd.
Wuhan Topule Biopharmaceutical Co., Ltd
Aladdin Scientific
Amadis Chemical Company Limited
Shanghai Boyle Chemical Co., Ltd.
Dalian Meilun Biotech Co., Ltd.