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ChemicalBook >> CAS DataBase List >> FIIN-3

FIIN-3

FIIN-3 price.
  • $41 - $1800
  • Product name: FIIN-3
  • CAS: 1637735-84-2
  • MF: C34H36Cl2N8O4
  • MW: 691.61
  • EINECS:
  • MDL Number:MFCD28386554
  • Synonyms:FIIN-3;FIN-3;FIIN3; FIIN 3;FIIN3; FIIN 3; FIIN-3;CS-2331;2-Propenamide, N-[4-[[[[(2,6-dichloro-3,5-dimethoxyphenyl)amino]carbonyl][6-[[4-(4-methyl-1-piperazinyl)phenyl]amino]-4-pyrimidinyl]amino]methyl]phenyl]-;Inhibitor,FIIN 3,FIIN-3,HER1,FIIN3,ErbB-1,Epidermal growth factor receptor,inhibit,Fibroblast growth factor receptor,EGFR,FGFR;FIIN-3, 10 mM in DMSO
Price36 Properties Safety Information Description
36 prices
Selected condition：
Brand
  • aablocks
  • AK Scientific
  • Arctom
  • Biorbyt Ltd
  • Cayman Chemical
  • ChemScene
  • DC Chemicals
  • TRC
Package
  • 10mM*1mLinDMSO
  • 1mg
  • 2mg
  • 10mM*1mLinDMSO(Solution)
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 250mg
  • 1g
  • 100mg
  • 10mM*1mLinDMSO(Solid+Solvent)
  • Manufactureraablocks
  • Product numberAA001UAX
  • Product descriptionFIIN-3
  • Packaging1mg
  • Price$47
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA001UAX
  • Product descriptionFIIN-3
  • Packaging2mg
  • Price$57
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA001UAX
  • Product descriptionFIIN-3
  • Packaging5mg
  • Price$79
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA001UAX
  • Product descriptionFIIN-3
  • Packaging10mg
  • Price$116
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA001UAX
  • Product descriptionFIIN-3
  • Packaging25mg
  • Price$233
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA001UAX
  • Product descriptionFIIN-3
  • Packaging50mg
  • Price$335
  • Updated2026-05-28
  • Buy
  • ManufacturerAK Scientific
  • Product number7571DW
  • Product descriptionN-[4-[[(2,6-Dichloro-3,5-dimethoxyphenyl)carbamoyl-[6-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]amino]methyl]phenyl]prop-2-enamide
  • Packaging1mg
  • Price$139
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberHY-18603
  • Product descriptionFIIN-3 99.01%
  • Packaging5mg
  • Price$143
  • Updated2026-05-26
  • Buy
  • ManufacturerArctom
  • Product numberHY-18603
  • Product descriptionFIIN-3 99.01%
  • Packaging1mg
  • Price$67
  • Updated2026-05-26
  • Buy
  • ManufacturerArctom
  • Product numberHY-18603
  • Product descriptionFIIN-3 99.01%
  • Packaging10mg
  • Price$243
  • Updated2026-05-26
  • Buy
  • ManufacturerArctom
  • Product numberHY-18603
  • Product descriptionFIIN-3 99.01%
  • Packaging10mM*1mLinDMSO(Solid+Solvent)
  • Price$207
  • Updated2026-05-26
  • Buy
  • ManufacturerArctom
  • Product numberHY-18603
  • Product descriptionFIIN-3 99.01%
  • Packaging10mM*1mLinDMSO(Solution)
  • Price$217
  • Updated2026-05-26
  • Buy
  • ManufacturerArctom
  • Product numberHY-18603
  • Product descriptionFIIN-3 99.01%
  • Packaging25mg
  • Price$509
  • Updated2026-05-26
  • Buy
  • ManufacturerArctom
  • Product numberHY-18603
  • Product descriptionFIIN-3 99.01%
  • Packaging50mg
  • Price$817
  • Updated2026-05-26
  • Buy
  • ManufacturerArctom
  • Product numberHY-18603
  • Product descriptionFIIN-3 99.01%
  • Packaging100mg
  • Price$1226
  • Updated2026-05-26
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb1223253
  • Product descriptionFIIN-3 >98%(HPLC)
  • Packaging50mg
  • Price$870
  • Updated2026-05-06
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA001UAX FIIN-3 1mg $47 2026-05-28 Buy
aablocks AA001UAX FIIN-3 2mg $57 2026-05-28 Buy
aablocks AA001UAX FIIN-3 5mg $79 2026-05-28 Buy
aablocks AA001UAX FIIN-3 10mg $116 2026-05-28 Buy
aablocks AA001UAX FIIN-3 25mg $233 2026-05-28 Buy
aablocks AA001UAX FIIN-3 50mg $335 2026-05-28 Buy
AK Scientific 7571DW N-[4-[[(2,6-Dichloro-3,5-dimethoxyphenyl)carbamoyl-[6-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]amino]methyl]phenyl]prop-2-enamide 1mg $139 2021-12-16 Buy
Arctom HY-18603 FIIN-3 99.01% 5mg $143 2026-05-26 Buy
Arctom HY-18603 FIIN-3 99.01% 1mg $67 2026-05-26 Buy
Arctom HY-18603 FIIN-3 99.01% 10mg $243 2026-05-26 Buy
Arctom HY-18603 FIIN-3 99.01% 10mM*1mLinDMSO(Solid+Solvent) $207 2026-05-26 Buy
Arctom HY-18603 FIIN-3 99.01% 10mM*1mLinDMSO(Solution) $217 2026-05-26 Buy
Arctom HY-18603 FIIN-3 99.01% 25mg $509 2026-05-26 Buy
Arctom HY-18603 FIIN-3 99.01% 50mg $817 2026-05-26 Buy
Arctom HY-18603 FIIN-3 99.01% 100mg $1226 2026-05-26 Buy
Biorbyt Ltd orb1223253 FIIN-3 >98%(HPLC) 50mg $870 2026-05-06 Buy
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Properties

Boiling point :909.4±65.0 °C(Predicted)
Density :1.379±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :Acetonitrile: sparingly soluble; Methanol: sparingly soluble
form :A crystalline solid
pka :10.78±0.70(Predicted)
color :White to off-white

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

FIIN-3 is an inhibitor of FGF receptors (FGFRs; IC50s = 13, 21, 31, and 35 nM for recombinant FGFR1-4, respectively). It is selective for FGFRs over a panel of 456 kinases at a concentration of 1 μM, however, it does inhibit EGFR (IC50 = 204 nM). FIIN-3 inhibits growth of Ba/F3 cells that are dependent on the kinase activity of wild-type FGFR1-4 as well as gatekeeper mutant FGFR2 and FGFR3 (EC50s = <1-69 nM) and inhibits FGFR-dependent signaling in a concentration-dependent manner in FGFR2TEL/V564M-dependent Ba/F3 cells. FIIN-3 also inhibits growth in a panel of cancer cell lines (EC50s = 1.4-499 nM).

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Suppliers and manufacturers

Shanghai Boyle Chemical Co., Ltd. Haoyuan Chemexpress Co., Ltd. MedChemexpress LLC HangZhou YuHao Chemical Technology Co., Ltd. Shanghai Lollane Biological Technology Co.,Ltd. ShangHai Siyan Biological Technology Co., Ltd. Shanghai YuanYe Biotechnology Co., Ltd. Tianjin Kailiqi Biotechnology Co., Ltd. Medi-tech Bioscientific Co., Ltd. Shanghai Kangman Biological Technology Co., Ltd.