FIPI
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- $44 - $2691.1
- Product name: FIPI
- CAS: 939055-18-2
- MF: C23H24FN5O2
- MW: 421.47
- EINECS:
- MDL Number:MFCD18382115
- Synonyms:FIPI;FIPI HYDROCHLORIDE;5-Fluoro-2-Indolyl des-Chlorohalopemide;N-[2-[4-(2,3-Dihydro-2-oxo-1H-benzimidazol-1-yl)-1-piperidinyl]ethyl]-5-fluoro-1H-indole-2-carboxamide;N-[2-[4-(2,3-Dihydro-2-oxo-1H-benzimidazol-1-yl)-1-piperidinyl]ethy]-5-fluoro-1H-indole-2-carboxamide hydrochloride;CS-1511; 5-fluoro-N-[2-[4-(2-oxo-3H-benzimidazol-1-yl)piperidin-1-yl]ethyl]-1H-indole-2-carboxamide;1H-Indole-2-carboxamide, N-[2-[4-(2,3-dihydro-2-oxo-1H-benzimidazol-1-yl)-1-piperidinyl]ethyl]-5-fluoro-
22 prices
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Brand
- American Custom Chemicals Corporation
- ApexBio Technology
- Biorbyt Ltd
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- DC Chemicals
- Sigma-Aldrich
- Tocris
- TRC
- Usbiological
Package
- 5MG
- 10mg
- 10
- 1mg
- 50
- 25mg
- 50mg
- 100mg
- 250mg
- 1000mg
- 5 mg
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberHCH0105888
- Product descriptionN-(2-(4-(2,3-DIHYDRO-2-OXO-1H-BENZIMIDAZOL-1-YL)-1-PIPERIDINYL)ETHYL)-5-FLUORO-1H-INDOLE-2-CARBOXAMIDE 95.00%
- Packaging5MG
- Price$498.97
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB7440
- Product descriptionFIPI
- Packaging5mg
- Price$146
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb181391
- Product descriptionFIPI >98%
- Packaging100mg
- Price$690.2
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb181391
- Product descriptionFIPI >98%
- Packaging250mg
- Price$1356.6
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb181391
- Product descriptionFIPI >98%
- Packaging1000mg
- Price$2691.1
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number13563
- Product descriptionFIPI ≥98%
- Packaging1mg
- Price$44
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number13563
- Product descriptionFIPI ≥98%
- Packaging5mg
- Price$130
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number13563
- Product descriptionFIPI ≥98%
- Packaging10mg
- Price$235
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number13563
- Product descriptionFIPI ≥98%
- Packaging25mg
- Price$533
- Updated2024-03-01
- Buy
- ManufacturerChemenu
- Product numberCM148885
- Product description5-fluoro-N-(2-(4-(2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)piperidin-1-yl)ethyl)-1H-indole-2-carboxamide 98%
- Packaging100mg
- Price$491
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-4183
- Product descriptionFIPI 99.49%
- Packaging5mg
- Price$84
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-4183
- Product descriptionFIPI 99.49%
- Packaging10mg
- Price$132
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-4183
- Product descriptionFIPI 99.49%
- Packaging50mg
- Price$480
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-4183
- Product descriptionFIPI 99.49%
- Packaging100mg
- Price$900
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD31000164
- Product descriptionFIPI 98+%
- Packaging50mg
- Price$455
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD31000164
- Product descriptionFIPI 98+%
- Packaging100mg
- Price$851
- Updated2021-12-16
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
American Custom Chemicals Corporation | HCH0105888 | N-(2-(4-(2,3-DIHYDRO-2-OXO-1H-BENZIMIDAZOL-1-YL)-1-PIPERIDINYL)ETHYL)-5-FLUORO-1H-INDOLE-2-CARBOXAMIDE 95.00% | 5MG | $498.97 | 2021-12-16 | Buy |
ApexBio Technology | B7440 | FIPI | 5mg | $146 | 2021-12-16 | Buy |
Biorbyt Ltd | orb181391 | FIPI >98% | 100mg | $690.2 | 2021-12-16 | Buy |
Biorbyt Ltd | orb181391 | FIPI >98% | 250mg | $1356.6 | 2021-12-16 | Buy |
Biorbyt Ltd | orb181391 | FIPI >98% | 1000mg | $2691.1 | 2021-12-16 | Buy |
Cayman Chemical | 13563 | FIPI ≥98% | 1mg | $44 | 2024-03-01 | Buy |
Cayman Chemical | 13563 | FIPI ≥98% | 5mg | $130 | 2024-03-01 | Buy |
Cayman Chemical | 13563 | FIPI ≥98% | 10mg | $235 | 2024-03-01 | Buy |
Cayman Chemical | 13563 | FIPI ≥98% | 25mg | $533 | 2024-03-01 | Buy |
Chemenu | CM148885 | 5-fluoro-N-(2-(4-(2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)piperidin-1-yl)ethyl)-1H-indole-2-carboxamide 98% | 100mg | $491 | 2021-12-16 | Buy |
ChemScene | CS-4183 | FIPI 99.49% | 5mg | $84 | 2021-12-16 | Buy |
ChemScene | CS-4183 | FIPI 99.49% | 10mg | $132 | 2021-12-16 | Buy |
ChemScene | CS-4183 | FIPI 99.49% | 50mg | $480 | 2021-12-16 | Buy |
ChemScene | CS-4183 | FIPI 99.49% | 100mg | $900 | 2021-12-16 | Buy |
Crysdot | CD31000164 | FIPI 98+% | 50mg | $455 | 2021-12-16 | Buy |
Crysdot | CD31000164 | FIPI 98+% | 100mg | $851 | 2021-12-16 | Buy |
Properties
Density :1.349±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMSO : 14.67 mg/mL (34.81 mM; Need ultrasonic and warming)
form :Powder
pka :12.04±0.30(Predicted)
color :Light yellow to khaki
storage temp. :Store at -20°C
solubility :DMSO : 14.67 mg/mL (34.81 mM; Need ultrasonic and warming)
form :Powder
pka :12.04±0.30(Predicted)
color :Light yellow to khaki
Safety Information
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Description
Isoforms of phospholipase D (PLD) cleave the head group from phospholipids, releasing the second messenger phosphatidic acid (PA), which can produce changes in Ras activation, cell spreading, stress fiber formation, chemotaxis, and membrane vesicle trafficking. FIPI is a derivative of halopemide which potently inhibits both PLD1 (IC50 = 25 nM) and PLD2 (IC50 = 20 nM). It also prevents PLD regulation of F-actin cytoskeleton reorganization, cell spreading, and chemotaxis. FIPI has good pharmacokinetic parameters in rats, with a half-life greater than five hours, a Cmax that, at 363 nM, is greater than 10-fold the IC50 versus PLD2, and bioavailability of 18%.Suppliers and manufacturers
career henan chemical co
ATK CHEMICAL COMPANY LIMITED
BOC Sciences
Zhejiang J&C Biological Technology Co.,Limited
InvivoChem
TargetMol Chemicals Inc.
ShenZhen Trendseen Biological Technology Co.,Ltd.
Wuhan Topule Biopharmaceutical Co., Ltd
Aladdin Scientific
$1.00 /1KG
5-fluoro-N-[2-[4-(2-oxo-3H-benzimidazol-1-yl)piperidin-1-yl]ethyl]-1H-indole-2-carboxamide CAS:939055-18-2
5-fluoro-N-[2-[4-(2-oxo-3H-benzimidazol-1-yl)piperidin-1-yl]ethyl]-1H-indole-2-carboxamide CAS:939055-18-2