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ChemicalBook >> CAS DataBase List >> FIPI

FIPI

FIPI price.
  • $44 - $2691.1
  • Product name: FIPI
  • CAS: 939055-18-2
  • MF: C23H24FN5O2
  • MW: 421.47
  • EINECS:
  • MDL Number:MFCD18382115
  • Synonyms:FIPI;FIPI HYDROCHLORIDE;5-Fluoro-2-Indolyl des-Chlorohalopemide;N-[2-[4-(2,3-Dihydro-2-oxo-1H-benzimidazol-1-yl)-1-piperidinyl]ethyl]-5-fluoro-1H-indole-2-carboxamide;N-[2-[4-(2,3-Dihydro-2-oxo-1H-benzimidazol-1-yl)-1-piperidinyl]ethy]-5-fluoro-1H-indole-2-carboxamide hydrochloride;CS-1511; 5-fluoro-N-[2-[4-(2-oxo-3H-benzimidazol-1-yl)piperidin-1-yl]ethyl]-1H-indole-2-carboxamide;1H-Indole-2-carboxamide, N-[2-[4-(2,3-dihydro-2-oxo-1H-benzimidazol-1-yl)-1-piperidinyl]ethyl]-5-fluoro-
22 prices
Selected condition:
Brand
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Biorbyt Ltd
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Sigma-Aldrich
  • Tocris
  • TRC
  • Usbiological
Package
  • 5MG
  • 10mg
  • 10
  • 1mg
  • 50
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 1000mg
  • 5 mg
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberHCH0105888
  • Product descriptionN-(2-(4-(2,3-DIHYDRO-2-OXO-1H-BENZIMIDAZOL-1-YL)-1-PIPERIDINYL)ETHYL)-5-FLUORO-1H-INDOLE-2-CARBOXAMIDE 95.00%
  • Packaging5MG
  • Price$498.97
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB7440
  • Product descriptionFIPI
  • Packaging5mg
  • Price$146
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb181391
  • Product descriptionFIPI >98%
  • Packaging100mg
  • Price$690.2
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb181391
  • Product descriptionFIPI >98%
  • Packaging250mg
  • Price$1356.6
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb181391
  • Product descriptionFIPI >98%
  • Packaging1000mg
  • Price$2691.1
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number13563
  • Product descriptionFIPI ≥98%
  • Packaging1mg
  • Price$44
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number13563
  • Product descriptionFIPI ≥98%
  • Packaging5mg
  • Price$130
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number13563
  • Product descriptionFIPI ≥98%
  • Packaging10mg
  • Price$235
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number13563
  • Product descriptionFIPI ≥98%
  • Packaging25mg
  • Price$533
  • Updated2024-03-01
  • Buy
  • ManufacturerChemenu
  • Product numberCM148885
  • Product description5-fluoro-N-(2-(4-(2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)piperidin-1-yl)ethyl)-1H-indole-2-carboxamide 98%
  • Packaging100mg
  • Price$491
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-4183
  • Product descriptionFIPI 99.49%
  • Packaging5mg
  • Price$84
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-4183
  • Product descriptionFIPI 99.49%
  • Packaging10mg
  • Price$132
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-4183
  • Product descriptionFIPI 99.49%
  • Packaging50mg
  • Price$480
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-4183
  • Product descriptionFIPI 99.49%
  • Packaging100mg
  • Price$900
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31000164
  • Product descriptionFIPI 98+%
  • Packaging50mg
  • Price$455
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31000164
  • Product descriptionFIPI 98+%
  • Packaging100mg
  • Price$851
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
American Custom Chemicals Corporation HCH0105888 N-(2-(4-(2,3-DIHYDRO-2-OXO-1H-BENZIMIDAZOL-1-YL)-1-PIPERIDINYL)ETHYL)-5-FLUORO-1H-INDOLE-2-CARBOXAMIDE 95.00% 5MG $498.97 2021-12-16 Buy
ApexBio Technology B7440 FIPI 5mg $146 2021-12-16 Buy
Biorbyt Ltd orb181391 FIPI >98% 100mg $690.2 2021-12-16 Buy
Biorbyt Ltd orb181391 FIPI >98% 250mg $1356.6 2021-12-16 Buy
Biorbyt Ltd orb181391 FIPI >98% 1000mg $2691.1 2021-12-16 Buy
Cayman Chemical 13563 FIPI ≥98% 1mg $44 2024-03-01 Buy
Cayman Chemical 13563 FIPI ≥98% 5mg $130 2024-03-01 Buy
Cayman Chemical 13563 FIPI ≥98% 10mg $235 2024-03-01 Buy
Cayman Chemical 13563 FIPI ≥98% 25mg $533 2024-03-01 Buy
Chemenu CM148885 5-fluoro-N-(2-(4-(2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)piperidin-1-yl)ethyl)-1H-indole-2-carboxamide 98% 100mg $491 2021-12-16 Buy
ChemScene CS-4183 FIPI 99.49% 5mg $84 2021-12-16 Buy
ChemScene CS-4183 FIPI 99.49% 10mg $132 2021-12-16 Buy
ChemScene CS-4183 FIPI 99.49% 50mg $480 2021-12-16 Buy
ChemScene CS-4183 FIPI 99.49% 100mg $900 2021-12-16 Buy
Crysdot CD31000164 FIPI 98+% 50mg $455 2021-12-16 Buy
Crysdot CD31000164 FIPI 98+% 100mg $851 2021-12-16 Buy

Properties

Density :1.349±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMSO : 14.67 mg/mL (34.81 mM; Need ultrasonic and warming)
form :Powder
pka :12.04±0.30(Predicted)
color :Light yellow to khaki

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

Isoforms of phospholipase D (PLD) cleave the head group from phospholipids, releasing the second messenger phosphatidic acid (PA), which can produce changes in Ras activation, cell spreading, stress fiber formation, chemotaxis, and membrane vesicle trafficking. FIPI is a derivative of halopemide which potently inhibits both PLD1 (IC50 = 25 nM) and PLD2 (IC50 = 20 nM). It also prevents PLD regulation of F-actin cytoskeleton reorganization, cell spreading, and chemotaxis. FIPI has good pharmacokinetic parameters in rats, with a half-life greater than five hours, a Cmax that, at 363 nM, is greater than 10-fold the IC50 versus PLD2, and bioavailability of 18%.