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ChemicalBook >> CAS DataBase List >> Flibanserin

Flibanserin

Flibanserin price.
  • $13 - $1000
  • Product name: Flibanserin
  • CAS: 167933-07-5
  • MF: C20H21F3N4O
  • MW: 390.4
  • EINECS:643-002-2
  • MDL Number:MFCD00918402
  • Synonyms:Flibanserin,Bimt 17, Bimt-17-BS,Girosa;Flibanserin;Bimt 17;3-[2-[4-[4-(Trifluoromethyl)phenyl]piperazin-1-yl]ethyl]-1H-benzimidazol-2-one;Flibanerins;BIMT 17BS;2H-Benzimidazol-2-one,1,3-dihydro-1-[2-[4-[3-(trifluoromethyl)phenyl]-1-piperazinyl]ethyl]-;Flibanserin(BIMT17)
32 prices
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Brand
  • Adipogen Life Sciences
  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Arctom
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Sigma-Aldrich
  • TRC
Package
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 1g
  • 5g
  • ManufacturerAdipogen Life Sciences
  • Product numberCDX-F0337-M005
  • Product descriptionFlibanserin ≥98%(HPLC)
  • Packaging5mg
  • Price$47
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number3427BB
  • Product descriptionFlibanserin
  • Packaging25mg
  • Price$66
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number3427BB
  • Product descriptionFlibanserin
  • Packaging5g
  • Price$116
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA101358
  • Product descriptionFlibanserin 98+%
  • Packaging5mg
  • Price$13
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA101358
  • Product descriptionFlibanserin 98+%
  • Packaging10mg
  • Price$22
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA101358
  • Product descriptionFlibanserin 98+%
  • Packaging25mg
  • Price$36
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA101358
  • Product descriptionFlibanserin 98+%
  • Packaging50mg
  • Price$71
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA101358
  • Product descriptionFlibanserin 98+%
  • Packaging1g
  • Price$284
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA101358
  • Product descriptionFlibanserin 98+%
  • Packaging5g
  • Price$575
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0006409
  • Product descriptionFLIBANSERIN 95.00%
  • Packaging10MG
  • Price$245.7
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC3123
  • Product descriptionFlibanserin
  • Packaging5mg
  • Price$62
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC3123
  • Product descriptionFlibanserin
  • Packaging10mg
  • Price$119
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC3123
  • Product descriptionFlibanserin
  • Packaging25mg
  • Price$234
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC3123
  • Product descriptionFlibanserin
  • Packaging50mg
  • Price$437
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS425091
  • Product descriptionFlibanserin ≥98%
  • Packaging250mg
  • Price$146
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS425091
  • Product descriptionFlibanserin ≥98%
  • Packaging1g
  • Price$360
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Adipogen Life Sciences CDX-F0337-M005 Flibanserin ≥98%(HPLC) 5mg $47 2021-12-16 Buy
AK Scientific 3427BB Flibanserin 25mg $66 2021-12-16 Buy
AK Scientific 3427BB Flibanserin 5g $116 2021-12-16 Buy
Ambeed A101358 Flibanserin 98+% 5mg $13 2021-12-16 Buy
Ambeed A101358 Flibanserin 98+% 10mg $22 2021-12-16 Buy
Ambeed A101358 Flibanserin 98+% 25mg $36 2021-12-16 Buy
Ambeed A101358 Flibanserin 98+% 50mg $71 2021-12-16 Buy
Ambeed A101358 Flibanserin 98+% 1g $284 2021-12-16 Buy
Ambeed A101358 Flibanserin 98+% 5g $575 2021-12-16 Buy
American Custom Chemicals Corporation API0006409 FLIBANSERIN 95.00% 10MG $245.7 2021-12-16 Buy
ApexBio Technology C3123 Flibanserin 5mg $62 2021-12-16 Buy
ApexBio Technology C3123 Flibanserin 10mg $119 2021-12-16 Buy
ApexBio Technology C3123 Flibanserin 25mg $234 2021-12-16 Buy
ApexBio Technology C3123 Flibanserin 50mg $437 2021-12-16 Buy
Arctom AS425091 Flibanserin ≥98% 250mg $146 2021-12-16 Buy
Arctom AS425091 Flibanserin ≥98% 1g $360 2021-12-16 Buy

Properties

Density :1.292±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: soluble10mg/mL, clear
form :powder
pka :12.12±0.30(Predicted)
color :white to beige
InChI :InChI=1S/C20H21F3N4O/c21-20(22,23)15-4-3-5-16(14-15)26-11-8-25(9-12-26)10-13-27-18-7-2-1-6-17(18)24-19(27)28/h1-7,14H,8-13H2,(H,24,28)
InChIKey :PPRRDFIXUUSXRA-UHFFFAOYSA-N
SMILES :C1(=O)N(CCN2CCN(C3=CC=CC(C(F)(F)F)=C3)CC2)C2=CC=CC=C2N1

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H301 Toxic if swalloed Acute toxicity,oral Category 3 Danger GHS hazard pictograms P264, P270, P301+P310, P321, P330,P405, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Flibanserin is a full agonist of the serotonin 5-HT1A receptor and an antagonist of 5-HT2A (Kis = 1 and 49 nM, respectively). It also binds to dopamine D4 receptors with Ki values ranging from 4-24 nM, but demonstrates no affinity for the other 5-HT subtypes or other neurotransmitter receptors. In vitro, flibanserin has been shown to reduce forskolin-stimulated cAMP formation in cells and rat tissues and to antagonize the accumulation of phosphatidyl inositol turnover induced by 5-HT in the mouse cortex. At 10 mg/kg, flibanserin can reduce serotonin in the prefrontal cortex and dorsal raphe of conscious rats while increasing extracellular noradrenaline and dopamine. Multifunctional serotonergic ligands like flibanserin that can enhance downstream release of dopamine and norepinephrine while concomitantly reducing serotonin release in the brain circuits that mediate symptoms of reduced sexual interest and desire are being studied clinically for therapeutic potential to improve sexual functioning.

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