Forodesine
- $36 - $660
- Product name: Forodesine
- CAS: 209799-67-7
- MF: C11H14N4O4
- MW: 266.25
- EINECS:
- MDL Number:MFCD09837827
- Synonyms:4H-Pyrrolo3,2-dpyrimidin-4-one, 7-(2S,3S,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)-2-pyrrolidinyl-1,5-dihydro-;Forodesine;7-[(2S,3S,4R,5R)-3,4-Dihydroxy-5-(hydroxymethyl)-2-pyrrolidinyl]-3,5-dihydro-4H-pyrrolo[3,2-d]pyrimidin-4-one;Fodosine;Immucillin-H;(1S)-1-(9-deazahypoxanthin-9-yl)-1,4-dideoxy-1,4-iMino-D-ribitol, iMMucillin H;FORODESINE FODOSINE;4H-Pyrrolo[3,2-d]pyriMidin-4-one,7-[(2S,3S,4R,5R)-3,4-dihydroxy-5-(hydroxyMethyl)-2-pyrrolidinyl]-3,5-dihydro-
9 prices
Selected condition:
Brand
- American Custom Chemicals Corporation
- Cayman Chemical
- Chemenu
- Crysdot
- TRC
Package
- 1mg
- 5MG
- 10mg
- 25mg
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0005210
- Product descriptionFORODESINE 95.00%
- Packaging5MG
- Price$660
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number30475
- Product descriptionForodesine
- Packaging1mg
- Price$36
- Updated2023-06-20
- Buy
- ManufacturerCayman Chemical
- Product number30475
- Product descriptionForodesine
- Packaging5mg
- Price$159
- Updated2023-06-20
- Buy
- ManufacturerCayman Chemical
- Product number30475
- Product descriptionForodesine
- Packaging10mg
- Price$194
- Updated2023-06-20
- Buy
- ManufacturerCayman Chemical
- Product number30475
- Product descriptionForodesine
- Packaging25mg
- Price$308
- Updated2023-06-20
- Buy
- ManufacturerChemenu
- Product numberCM152255
- Product description7-((2S,3S,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)pyrrolidin-2-yl)-3,5-dihydro-4H-pyrrolo[3,2-d]pyrimidin-4-one 98%
- Packaging10mg
- Price$589
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD31002706
- Product descriptionFodosine 98+%
- Packaging5mg
- Price$347
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD31002706
- Product descriptionFodosine 98+%
- Packaging10mg
- Price$624
- Updated2021-12-16
- Buy
- ManufacturerTRC
- Product numberF754540
- Product descriptionFodosine
- Packaging1mg
- Price$55
- Updated2021-12-16
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
American Custom Chemicals Corporation | API0005210 | FORODESINE 95.00% | 5MG | $660 | 2021-12-16 | Buy |
Cayman Chemical | 30475 | Forodesine | 1mg | $36 | 2023-06-20 | Buy |
Cayman Chemical | 30475 | Forodesine | 5mg | $159 | 2023-06-20 | Buy |
Cayman Chemical | 30475 | Forodesine | 10mg | $194 | 2023-06-20 | Buy |
Cayman Chemical | 30475 | Forodesine | 25mg | $308 | 2023-06-20 | Buy |
Chemenu | CM152255 | 7-((2S,3S,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)pyrrolidin-2-yl)-3,5-dihydro-4H-pyrrolo[3,2-d]pyrimidin-4-one 98% | 10mg | $589 | 2021-12-16 | Buy |
Crysdot | CD31002706 | Fodosine 98+% | 5mg | $347 | 2021-12-16 | Buy |
Crysdot | CD31002706 | Fodosine 98+% | 10mg | $624 | 2021-12-16 | Buy |
TRC | F754540 | Fodosine | 1mg | $55 | 2021-12-16 | Buy |
Properties
Boiling point :613.5±65.0 °C(Predicted)
Density :2.01
storage temp. :Hygroscopic, Refrigerator, under inert atmosphere
solubility :PBS (pH 7.2): 5 mg/ml
form :A crystalline solid
pka :13.88±0.70(Predicted)
color :Light brown to gray
Density :2.01
storage temp. :Hygroscopic, Refrigerator, under inert atmosphere
solubility :PBS (pH 7.2): 5 mg/ml
form :A crystalline solid
pka :13.88±0.70(Predicted)
color :Light brown to gray
Safety Information
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Signal word: | Warning | |||||||
Hazard statements: |
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Precautionary statements: |
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Description
Forodesine is a purine nucleoside analog and purine nucleoside phosphorylase (PNP) inhibitor (IC50s = 1.19, 0.48, 1.24, 0.66, and 1.57 nM for human, mouse, rat, monkey, and dog PNP, respectively). It inhibits phytohemagglutinin A-, mixed lymphocyte reaction-, or IL-2-induced proliferation of isolated human peripheral blood lymphocytes (PBLs; IC50s = <0.1-0.38 μM) in the presence, but not absence, of 2’-deoxyguanosine (dGuo). Forodesine inhibits proliferation of CEM-SS T cell acute lymphoblastic leukemia (T-ALL) cells. In vivo, forodesine (10 mg/kg) prolongs survival in the hu-PBL-SCID mouse model of xenogeneic graft versus host disease (GVHD).Related product price
- 1-Methyl-2-pyrrolidinone
$10-13970 - Polyvinylpyrrolidone cross-linked
$10-16520 - Polyvinylpyrrolidone
$15-9201.92