Forodesine
|
- $36 - $660
- Product name: Forodesine
- CAS: 209799-67-7
- MF: C11H14N4O4
- MW: 266.25
- EINECS:
- MDL Number:MFCD09837827
- Synonyms:4H-Pyrrolo3,2-dpyrimidin-4-one, 7-(2S,3S,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)-2-pyrrolidinyl-1,5-dihydro-;Forodesine;7-[(2S,3S,4R,5R)-3,4-Dihydroxy-5-(hydroxymethyl)-2-pyrrolidinyl]-3,5-dihydro-4H-pyrrolo[3,2-d]pyrimidin-4-one;Fodosine;Immucillin-H;(1S)-1-(9-deazahypoxanthin-9-yl)-1,4-dideoxy-1,4-iMino-D-ribitol, iMMucillin H;FORODESINE FODOSINE;4H-Pyrrolo[3,2-d]pyriMidin-4-one,7-[(2S,3S,4R,5R)-3,4-dihydroxy-5-(hydroxyMethyl)-2-pyrrolidinyl]-3,5-dihydro-
9 prices
Selected condition：
Brand
- American Custom Chemicals Corporation
- Cayman Chemical
- Chemenu
- Crysdot
- TRC
Package
- 1mg
- 5MG
- 10mg
- 25mg
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0005210
- Product descriptionFORODESINE 95.00%
- Packaging5MG
- Price$660
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number30475
- Product descriptionForodesine
- Packaging25mg
- Price$308
- Updated2023-06-20
- Buy
- ManufacturerCayman Chemical
- Product number30475
- Product descriptionForodesine
- Packaging10mg
- Price$194
- Updated2023-06-20
- Buy
- ManufacturerCayman Chemical
- Product number30475
- Product descriptionForodesine
- Packaging5mg
- Price$159
- Updated2023-06-20
- Buy
- ManufacturerCayman Chemical
- Product number30475
- Product descriptionForodesine
- Packaging1mg
- Price$36
- Updated2023-06-20
- Buy
- ManufacturerChemenu
- Product numberCM152255
- Product description7-((2S,3S,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)pyrrolidin-2-yl)-3,5-dihydro-4H-pyrrolo[3,2-d]pyrimidin-4-one 98%
- Packaging10mg
- Price$589
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD31002706
- Product descriptionFodosine 98+%
- Packaging5mg
- Price$347
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD31002706
- Product descriptionFodosine 98+%
- Packaging10mg
- Price$624
- Updated2021-12-16
- Buy
- ManufacturerTRC
- Product numberF754540
- Product descriptionFodosine
- Packaging1mg
- Price$55
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| American Custom Chemicals Corporation | API0005210 | FORODESINE 95.00% | 5MG | $660 | 2021-12-16 | Buy |
| Cayman Chemical | 30475 | Forodesine | 25mg | $308 | 2023-06-20 | Buy |
| Cayman Chemical | 30475 | Forodesine | 10mg | $194 | 2023-06-20 | Buy |
| Cayman Chemical | 30475 | Forodesine | 5mg | $159 | 2023-06-20 | Buy |
| Cayman Chemical | 30475 | Forodesine | 1mg | $36 | 2023-06-20 | Buy |
| Chemenu | CM152255 | 7-((2S,3S,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)pyrrolidin-2-yl)-3,5-dihydro-4H-pyrrolo[3,2-d]pyrimidin-4-one 98% | 10mg | $589 | 2021-12-16 | Buy |
| Crysdot | CD31002706 | Fodosine 98+% | 5mg | $347 | 2021-12-16 | Buy |
| Crysdot | CD31002706 | Fodosine 98+% | 10mg | $624 | 2021-12-16 | Buy |
| TRC | F754540 | Fodosine | 1mg | $55 | 2021-12-16 | Buy |
Properties
Boiling point :613.5±65.0 °C(Predicted)
Density :2.01
storage temp. :Hygroscopic, Refrigerator, under inert atmosphere
solubility :PBS (pH 7.2): 5 mg/ml
form :A crystalline solid
pka :13.88±0.70(Predicted)
color :Light brown to gray
Density :2.01
storage temp. :Hygroscopic, Refrigerator, under inert atmosphere
solubility :PBS (pH 7.2): 5 mg/ml
form :A crystalline solid
pka :13.88±0.70(Predicted)
color :Light brown to gray
Safety Information
| Symbol(GHS): |
|
|||||||
|---|---|---|---|---|---|---|---|---|
| Signal word: | Warning | |||||||
| Hazard statements: |
|
|||||||
| Precautionary statements: |
|
Description
Forodesine is a purine nucleoside analog and purine nucleoside phosphorylase (PNP) inhibitor (IC50s = 1.19, 0.48, 1.24, 0.66, and 1.57 nM for human, mouse, rat, monkey, and dog PNP, respectively). It inhibits phytohemagglutinin A-, mixed lymphocyte reaction-, or IL-2-induced proliferation of isolated human peripheral blood lymphocytes (PBLs; IC50s = <0.1-0.38 μM) in the presence, but not absence, of 2’-deoxyguanosine (dGuo). Forodesine inhibits proliferation of CEM-SS T cell acute lymphoblastic leukemia (T-ALL) cells. In vivo, forodesine (10 mg/kg) prolongs survival in the hu-PBL-SCID mouse model of xenogeneic graft versus host disease (GVHD).Related product price
- 1-Methyl-2-pyrrolidinone
$10-13970 - Polyvinylpyrrolidone cross-linked
$10-16520 - Polyvinylpyrrolidone
$15-9201.92
Suppliers and manufacturers
CONIER CHEM AND PHARMA LIMITED
Baoji Guokang Bio-Technology Co., Ltd.
Hefei Hirisun Pharmatech Co., Ltd
NewCan Biotech Limited
Hefei TNJ Chemical Industry Co.,Ltd.
Aladdin Scientific
Suzhou ARTK Medchem Co., Ltd.
Shanghai Hanhong Scientific Co., Ltd.
Amadis Chemical Company Limited
