Welcome to chemicalbook!
China English Japan Germany
010-86108875
18162-48-6872-50-4Methylene ChloridenaphthaleneTHFTitanium Dioxide
Structure Search
RFQ
Try our best to find the right business for you.
Messages
Do not miss inquiry messages Please log in to view all inquiry messages.
My chemicalbook Sign in

Welcome back!

RFQ
skype
MY Account
Top
ChemicalBook >> CAS DataBase List >> GSK2110183B

GSK2110183B

GSK2110183B price.
  • $40 - $1750
  • Product name: GSK2110183B
  • CAS: 1047645-82-8
  • MF: C18H18Cl3FN4OS
  • MW: 463.78
  • EINECS:
  • MDL Number:MFCD28167824
  • Synonyms:Afuresertib (hydrochloride);GSK 2110183B;GSK2110183B;GSK-2110183B;GSK 2110183 hydrochloride;GSK2110183 hydrochloride;GSK-2110183 hydrochloride;N-((S)-1-Amino-3-(3-fluorophenyl)propan-2-yl)-5-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)thiophene-2-carboxamide hydrochloride
Price16 Properties Safety Information Description
16 prices
Selected condition：
Brand
  • ACHEMBLOCK
  • Axon Medchem
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • DC Chemicals
Package
  • 1mg
  • 5MG
  • 10MG
  • 25mg
  • 50mg
  • 100MG
  • 1g
  • ManufacturerACHEMBLOCK
  • Product numberL13491
  • Product description(S)-N-(1-amino-3-(3-fluorophenyl)propan-2-yl)-5-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)thiophene-2-carboxamidehydrochloride 98%
  • Packaging5MG
  • Price$275
  • Updated2021-12-16
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberL13491
  • Product description(S)-N-(1-amino-3-(3-fluorophenyl)propan-2-yl)-5-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)thiophene-2-carboxamidehydrochloride 98%
  • Packaging10MG
  • Price$450
  • Updated2021-12-16
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberL13491
  • Product description(S)-N-(1-amino-3-(3-fluorophenyl)propan-2-yl)-5-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)thiophene-2-carboxamidehydrochloride 98%
  • Packaging100MG
  • Price$1750
  • Updated2021-12-16
  • Buy
  • ManufacturerAxon Medchem
  • Product numberAxon2460
  • Product descriptionGSK2110183hydrochloride-Afuresertibhydrochloride 99%
  • Packaging25mg
  • Price$401.5
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number17988
  • Product descriptionAfuresertib (hydrochloride) ≥98%
  • Packaging1mg
  • Price$40
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number17988
  • Product descriptionAfuresertib (hydrochloride) ≥98%
  • Packaging5mg
  • Price$138
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number17988
  • Product descriptionAfuresertib (hydrochloride) ≥98%
  • Packaging10mg
  • Price$254
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number17988
  • Product descriptionAfuresertib (hydrochloride)
  • Packaging25mg
  • Price$583
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-3385
  • Product descriptionAfuresertib(hydrochloride) 98.02%
  • Packaging5mg
  • Price$84
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-3385
  • Product descriptionAfuresertib(hydrochloride) 98.02%
  • Packaging10mg
  • Price$114
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-3385
  • Product descriptionAfuresertib(hydrochloride) 98.02%
  • Packaging50mg
  • Price$324
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-3385
  • Product descriptionAfuresertib(hydrochloride) 98.02%
  • Packaging100mg
  • Price$564
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31004715
  • Product descriptionAfuresertibhydrochloride 98+%
  • Packaging50mg
  • Price$534
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31004715
  • Product descriptionAfuresertibhydrochloride 98+%
  • Packaging100mg
  • Price$810
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC7994
  • Product descriptionAfuresertibHCl >98%
  • Packaging100mg
  • Price$400
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC7994
  • Product descriptionAfuresertibHCl >98%
  • Packaging1g
  • Price$1700
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
ACHEMBLOCK L13491 (S)-N-(1-amino-3-(3-fluorophenyl)propan-2-yl)-5-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)thiophene-2-carboxamidehydrochloride 98% 5MG $275 2021-12-16 Buy
ACHEMBLOCK L13491 (S)-N-(1-amino-3-(3-fluorophenyl)propan-2-yl)-5-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)thiophene-2-carboxamidehydrochloride 98% 10MG $450 2021-12-16 Buy
ACHEMBLOCK L13491 (S)-N-(1-amino-3-(3-fluorophenyl)propan-2-yl)-5-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)thiophene-2-carboxamidehydrochloride 98% 100MG $1750 2021-12-16 Buy
Axon Medchem Axon2460 GSK2110183hydrochloride-Afuresertibhydrochloride 99% 25mg $401.5 2021-12-16 Buy
Cayman Chemical 17988 Afuresertib (hydrochloride) ≥98% 1mg $40 2024-03-01 Buy
Cayman Chemical 17988 Afuresertib (hydrochloride) ≥98% 5mg $138 2024-03-01 Buy
Cayman Chemical 17988 Afuresertib (hydrochloride) ≥98% 10mg $254 2024-03-01 Buy
Cayman Chemical 17988 Afuresertib (hydrochloride) 25mg $583 2024-03-01 Buy
ChemScene CS-3385 Afuresertib(hydrochloride) 98.02% 5mg $84 2021-12-16 Buy
ChemScene CS-3385 Afuresertib(hydrochloride) 98.02% 10mg $114 2021-12-16 Buy
ChemScene CS-3385 Afuresertib(hydrochloride) 98.02% 50mg $324 2021-12-16 Buy
ChemScene CS-3385 Afuresertib(hydrochloride) 98.02% 100mg $564 2021-12-16 Buy
Crysdot CD31004715 Afuresertibhydrochloride 98+% 50mg $534 2021-12-16 Buy
Crysdot CD31004715 Afuresertibhydrochloride 98+% 100mg $810 2021-12-16 Buy
DC Chemicals DC7994 AfuresertibHCl >98% 100mg $400 2021-12-16 Buy
DC Chemicals DC7994 AfuresertibHCl >98% 1g $1700 2021-12-16 Buy

Properties

storage temp. :Store at -20°C, protect from light, stored under nitrogen
solubility :DMSO:65.0(Max Conc. mg/mL);140.15(Max Conc. mM)
DMF:50.0(Max Conc. mg/mL);107.81(Max Conc. mM)
Ethanol:50.0(Max Conc. mg/mL);107.81(Max Conc. mM)
Ethanol:PBS (pH 7.2) (1:1):0.5(Max Conc. mg/mL);1.08(Max Conc. mM) form :A crystalline solid
color :Yellow to brown

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312 Call a POISON CENTER or doctor/physician if you feel unwell.
P321 Specific treatment (see … on this label).
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P362 Take off contaminated clothing and wash before reuse.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

Afuresertib is a selective, orally bioavailable inhibitor of Akt1, 2, and 3 with Ki values of 0.08, 2, and 2.6 nM, respectively. It preferentially inhibits the proliferation of human cancer cell lines with Akt pathway activation and various cell lines derived from hematologic malignancies with minimal effect on glucose homeostasis. Afuresertib demonstrates activity against multiple myeloma in both preclinical and clinical models.

Suppliers and manufacturers

HANGZHOU CLAP TECHNOLOGY CO.,LTD
Zhejiang J&C Biological Technology Co.,Limited
InvivoChem
TargetMol Chemicals Inc.
ShenZhen Trendseen Biological Technology Co.,Ltd.
Zibo Hangyu Biotechnology Development Co., Ltd
HANGZHOU LEAP CHEM CO., LTD.
Aladdin Scientific
Suzhou ARTK Medchem Co., Ltd.
Amadis Chemical Company Limited